Popoli, Maurizio

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

Popoli, M., Yan, Z., McEwen, B. S., & Sanacora, G. (2012) · Nature Reviews Neuroscience

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

Cited by 1,393

Towards a glutamate hypothesis of depression

Sanacora, G., Treccani, G., & Popoli, M. (2012) · Neuropharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 1,036

Signaling Pathways Regulating Gene Expression, Neuroplasticity, and Neurotrophic Mechanisms in the Action of Antidepressants: A Critical Overview

Tardito, D., Perez, J., Tiraboschi, E., Musazzi, L., Racagni, G., & Popoli, M. (2006) · Pharmacological Reviews

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 303

How can drug discovery for psychiatric disorders be improved?

Agid, Y., Buzsáki, G., Diamond, D. M., Frackowiak, R., Giedd, J., Girault, J.-A., Grace, A., Lambert, J. J., Manji, H., Mayberg, H., et al. (2007) · Nature Reviews Drug Discovery

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 240

The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders

Sanacora, G., Yan, Z., & Popoli, M. (2022) · Nature Reviews Neuroscience

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

Cited by 197

Cellular and molecular mechanisms in the long-term action of antidepressants.

Racagni, G., & Popoli, M. (2008) · Dialogues in Clinical Neuroscience

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 192

Glutamatergic Neurotransmission: Pathway to Developing Novel Rapid-Acting Antidepressant Treatments

Kadriu, B., Musazzi, L., Henter, I. D., Graves, M., Popoli, M., & Zarate, C. A. (2019) · International Journal of Neuropsychopharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 165

Stress and corticosterone increase the readily releasable pool of glutamate vesicles in synaptic terminals of prefrontal and frontal cortex

Treccani, G., Musazzi, L., Perego, C., Milanese, M., Nava, N., Bonifacino, T., Lamanna, J., Malgaroli, A., Drago, F., Racagni, G., et al. (2014) · Molecular Psychiatry

Neuroscience and Neuropharmacology ResearchStress Responses and Cortisol

Cited by 133

Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants.

Baj, G., D'Alessandro, V., Musazzi, L., Mallei, A., Sartori, C. R., Sciancalepore, M., Tardito, D., Langone, F., Popoli, M., & Tongiorgi, E. (2012) · Neuropsychopharmacology

Nerve injury and regenerationTreatment of Major Depression

Cited by 103

Chronic mild stress induces anhedonic behavior and changes in glutamate release, BDNF trafficking and dendrite morphology only in stress vulnerable rats. The rapid restorative action of ketamine

Tornese, P., Sala, N., Bonini, D., Bonifacino, T., La Via, L., Milanese, M., Treccani, G., Seguini, M., Ieraci, A., Mingardi, J., et al. (2019) · Neurobiology of Stress

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 101

Functional and Structural Remodeling of Glutamate Synapses in Prefrontal and Frontal Cortex Induced by Behavioral Stress

Musazzi, L., Treccani, G., & Popoli, M. (2015) · Frontiers in Psychiatry

Neuroscience and Neuropharmacology ResearchStress Responses and Cortisol

Cited by 83

S-Ketamine Reverses Hippocampal Dendritic Spine Deficits in Flinders Sensitive Line Rats Within 1 h of Administration

Treccani, G., Ardalan, M., Chen, F., Musazzi, L., Popoli, M., Wegener, G., Nyengaard, J. R., & Müller, H. K. (2019) · Molecular Neurobiology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 73

Association between the ionotropic glutamate receptor kainate 3 (GRIK3) ser310ala polymorphism and schizophrenia

Begni, S., Popoli, M., Moraschi, S., Bignotti, S., Tura, G. B., & Gennarelli, M. (2002) · Molecular Psychiatry

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 71

Positive AMPA receptor modulation in the treatment of neuropsychiatric disorders: A long and winding road

Kadriu, B., Musazzi, L., Johnston, J. N., Kalynchuk, L. E., Caruncho, H. J., Popoli, M., & Zarate, C. A. (2021) · Drug Discovery Today

Neuroscience and Neuropharmacology ResearchTreatment of Major Depression

Cited by 62

Ketamine regulates the presynaptic release machinery in the hippocampus

Müller, H. K., Wegener, G., Liebenberg, N., Zarate, C. A., Popoli, M., & Elfving, B. (2013) · Journal of Psychiatric Research

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 61

miR-9-5p is involved in the rescue of stress-dependent dendritic shortening of hippocampal pyramidal neurons induced by acute antidepressant treatment with ketamine

Mingardi, J., La Via, L., Tornese, P., Carini, G., Trontti, K., Seguini, M., Tardito, D., Bono, F., Fiorentini, C., Elia, L., et al. (2021) · Neurobiology of Stress

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 36

Chronic Desipramine Prevents Acute Stress-Induced Reorganization of Medial Prefrontal Cortex Architecture by Blocking Glutamate Vesicle Accumulation and Excitatory Synapse Increase

Nava, N., Treccani, G., Liebenberg, N., Chen, F., Popoli, M., Wegener, G., & Nyengaard, J. R. (2015) · International Journal of Neuropsychopharmacology

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

Cited by 32