Eils, Roland

Complement activation induces excessive T cell cytotoxicity in severe COVID-19

Georg, P., Astaburuaga-García, R., Bonaguro, L., Brumhard, S., Michalick, L., Lippert, L. J., Kostevc, T., Gäbel, C., Schneider, M., Streitz, M., et al. (2022) · Cell

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 218

Web-based design and analysis tools for CRISPR base editing

Hwang, G.-H., Park, J., Lim, K., Kim, S., Yu, J., Yu, E., Kim, S.-T., Eils, R., Kim, J.-S., & Bae, S. (2018) · BMC Bioinformatics

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 198

Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL

Fricker, N., Beaudouin, J., Richter, P., Eils, R., Krammer, P. H., & Lavrik, I. N. (2010) · Journal of Cell Biology

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 154

Prognostic Impact of Gene Expression–Based Classification for Neuroblastoma

Oberthuer, A., Hero, B., Berthold, F., Juraeva, D., Faldum, A., Kahlert, Y., Asgharzadeh, S., Seeger, R., Scaruffi, P., Tonini, G. P., et al. (2010) · Journal of Clinical Oncology

Neuroblastoma Research and TreatmentsBreast Cancer Treatment Studies

Cited by 135

Optimal Experimental Design for Parameter Estimation of a Cell Signaling Model

Bandara, S., Schlöder, J. P., Eils, R., Bock, H. G., & Meyer, T. (2009) · PLoS Computational Biology

Gene Regulatory Network AnalysisOptimal Experimental Design Methods

Cited by 135

Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer

Ishaque, N., Abba, M. L., Hauser, C., Patil, N., Paramasivam, N., Huebschmann, D., Leupold, J. H., Balasubramanian, G. P., Kleinheinz, K., Toprak, U. H., et al. (2018) · Nature Communications

Cancer Genomics and DiagnosticsColorectal Cancer Treatments and Studies

Cited by 132

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype

Wu, Y., Fletcher, M., Gu, Z., Wang, Q., Costa, B., Bertoni, A., Man, K.-H., Schlotter, M., Felsberg, J., Mangei, J., et al. (2020) · Nature Communications

Glioma Diagnosis and TreatmentEpigenetics and DNA Methylation

Cited by 101

Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer

Jäger, N., Schlesner, M., Jones, D. T. W., Raffel, S., Mallm, J.-P., Junge, K. M., Weichenhan, D., Bauer, T., Ishaque, N., Kool, M., et al. (2013) · Cell

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 90

BioModels: expanding horizons to include more modelling approaches and formats

Glont, M., Nguyen, T. V. N., Graesslin, M., Hälke, R., Ali, R., Schramm, J., Wimalaratne, S. M., Kothamachu, V. B., Rodriguez, N., Swat, M. J., et al. (2018) · Nucleic Acids Research

Gene Regulatory Network AnalysisScientific Computing and Data Management

Cited by 89

Intra- and Interdimeric Caspase-8 Self-Cleavage Controls Strength and Timing of CD95-Induced Apoptosis

Kallenberger, S. M., Beaudouin, J., Claus, J., Fischer, C., Sorger, P. K., Legewie, S., & Eils, R. (2014) · Science Signaling

Cell death mechanisms and regulationGene Regulatory Network Analysis

Cited by 76

Temporal control of the integrated stress response by a stochastic molecular switch

Klein, P., Kallenberger, S. M., Roth, H., Roth, K., Ly-Hartig, T. B. N., Magg, V., Aleš, J., Talemi, S. R., Qiang, Y., Wolf, S., et al. (2022) · Science Advances

Endoplasmic Reticulum Stress and DiseaseRNA and protein synthesis mechanisms

Cited by 50

Temporal control of the integrated stress response by a stochastic molecular switch

Klein, P., Kallenberger, S. M., Roth, H., Roth, K., Ly-Hartig, T. B. N., Magg, V., Aleš, J., Talemi, S. R., Qiang, Y., Wolf, S., et al. (2022) · Science Advances

Endoplasmic Reticulum Stress and DiseaseRNA and protein synthesis mechanisms

Cited by 50

Early-onset childhood atopic dermatitis is related to NLRP2 repression

Thürmann, L., Grützmann, K., Klös, M., Bieg, M., Winter, M., Polte, T., Bauer, T., Schick, M., Bewerunge-Hudler, M., Röder, S., et al. (2018) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesInflammasome and immune disorders

Cited by 26