Rabinovitch, Marlene

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Nakahira, K., Haspel, J. A., Rathinam, V. A. K., Lee, S.-J., Dolinay, T., Lam, H. C., Englert, J. A., Rabinovitch, M., Cernadas, M., Kim, H. P., et al. (2011) · Nature Immunology

Inflammasome and immune disordersAutophagy in Disease and Therapy

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Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension

Rabinovitch, M., Guignabert, C., Humbert, M., & Nicolls, M. R. (2014) · Circulation Research

Pulmonary Hypertension Research and TreatmentsCardiac Fibrosis and Remodeling

Cited by 1,029

An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension

Hansmann, G., de Jesus Perez, V. A., Alastalo, T.-P., Alvira, C. M., Guignabert, C., Bekker, J. M., Schellong, S., Urashima, T., Wang, L., Morrell, N. W., et al. (2008) · Journal of Clinical Investigation

Pulmonary Hypertension Research and TreatmentsTGF-β signaling in diseases

Cited by 367

Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension.

Lee, S.-J., Smith, A., Guo, L., Alastalo, T.-P., Li, M., Sawada, H., Liu, X., Chen, Z.-H., Ifedigbo, E., Jin, Y., et al. (2011) · American Journal of Respiratory and Critical Care Medicine

Pulmonary Hypertension Research and TreatmentsAutophagy in Disease and Therapy

Cited by 217

Cellular senescence impairs the reversibility of pulmonary arterial hypertension

van der Feen, D. E., Bossers, G. P. L., Hagdorn, Q. A. J., Moonen, J.-R., Kurakula, K., Szulcek, R., Chappell, J., Vallania, F., Donato, M., Kok, K., et al. (2020) · Science Translational Medicine

Pulmonary Hypertension Research and TreatmentsTelomeres, Telomerase, and Senescence

Cited by 150

Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy

Sayed, N., Liu, C., Ameen, M., Himmati, F., Zhang, J. Z., Khanamiri, S., Moonen, J.-R., Wnorowski, A., Cheng, L., Rhee, J.-W., et al. (2020) · Science Translational Medicine

Pluripotent Stem Cells ResearchCardiomyopathy and Myosin Studies

Cited by 111

Enhanced ERK-1/2 activation in mice susceptible to coxsackievirus-induced myocarditis

Opavsky, M. A., Martino, T., Rabinovitch, M., Penninger, J., Richardson, C., Petric, M., Trinidad, C., Butcher, L., Chan, J., & Liu, P. P. (2002) · Journal of Clinical Investigation

Viral Infections and Immunology ResearchCardiac Fibrosis and Remodeling

Cited by 91

Developmental expression of LC3α and β: Absence of fibronectin or autophagy phenotype in LC3β knockout mice

Cann, G. M., Guignabert, C., Ying, L., Deshpande, N., Bekker, J. M., Wang, L., Zhou, B., & Rabinovitch, M. (2008) · Developmental Dynamics

Autophagy in Disease and TherapyDevelopmental Biology and Gene Regulation

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