Gorospe, Myriam

Skewed macrophage polarization in aging skeletal muscle

Cui, C., Driscoll, R. K., Piao, Y., Chia, C. W., Gorospe, M., & Ferrucci, L. (2019) · Aging Cell

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 117

HuR Uses AUF1 as a Cofactor To Promote p16INK4 mRNA Decay

Chang, N., Yi, J., Guo, G., Liu, X., Shang, Y., Tong, T., Cui, Q., Zhan, M., Gorospe, M., & Wang, W. (2010) · Molecular and Cellular Biology

RNA Research and SplicingRNA regulation and disease

Cited by 112

RNA-Binding Protein HuD Controls Insulin Translation

Lee, E. K., Kim, W., Tominaga, K., Martindale, J. L., Yang, X., Subaran, S. S., Carlson, O. D., Mercken, E. M., Kulkarni, R. N., Akamatsu, W., et al. (2012) · Molecular Cell

Pancreatic function and diabetesRNA Research and Splicing

Cited by 108

Increased stability of the p16 mRNA with replicative senescence

Wang, W., Martindale, J. L., Yang, X., Chrest, F. J., & Gorospe, M. (2005) · The EMBO Reports

RNA Research and SplicingTelomeres, Telomerase, and Senescence

Cited by 101

SASP regulation by noncoding RNA

Panda, A. C., Abdelmohsen, K., & Gorospe, M. (2017) · Mechanisms of Ageing and Development

Telomeres, Telomerase, and SenescenceCancer-related molecular mechanisms research

Cited by 86

Transcriptome signature of cellular senescence

Casella, G., Munk, R., Kim, K. M., Piao, Y., De, S., Abdelmohsen, K., & Gorospe, M. (2019) · Nucleic Acids Research

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 83

The YAP-TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress

Anerillas, C., Mazan-Mamczarz, K., Herman, A. B., Munk, R., Lam, K.-W. G., Calvo-Rubio, M., Garrido, A., Tsitsipatis, D., Martindale, J. L., Altés, G., et al. (2023) · Nature Aging

Telomeres, Telomerase, and SenescenceHippo pathway signaling and YAP/TAZ

Cited by 76

Early SRC activation skews cell fate from apoptosis to senescence

Anerillas, C., Herman, A. B., Rossi, M., Munk, R., Lehrmann, E., Martindale, J. L., Cui, C.-Y., Abdelmohsen, K., De, S., & Gorospe, M. (2022) · Science Advances

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 71

DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice

Herman, A. B., Tsitsipatis, D., Anerillas, C., Mazan-Mamczarz, K., Carr, A. E., Gregg, J. M., Wang, M., Zhang, J., Michel, M., Henry-Smith, C. A., et al. (2023) · Journal of Clinical Investigation

Telomeres, Telomerase, and SenescenceAtherosclerosis and Cardiovascular Diseases

Cited by 50

NF90 coordinately represses the senescence-associated secretory phenotype

Tominaga-Yamanaka, K., Abdelmohsen, K., Martindale, J. L., Yang, X., Taub, D. D., & Gorospe, M. (2012) · Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 49

A brain proteomic signature of incipient Alzheimer’s disease in young APOE ε4 carriers identifies novel drug targets

Roberts, J. A., Varma, V. R., An, Y., Varma, S., Candia, J., Fantoni, G., Tiwari, V., Anerillas, C., Williamson, A., Saito, A., et al. (2021) · Science Advances

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 49

Single-cell and spatial transcriptomics map senescent vascular cells in arterial remodeling during atherosclerosis in mice

Mazan-Mamczarz, K., Tsitsipatis, D., Childs, B. G., Carr, A. E., Dos Santos, C. R., Anerillas, C., Romero, B., Gregg, J. M., Henry-Smith, C., Okereke, A. N., et al. (2025) · Nature Aging

Telomeres, Telomerase, and SenescenceAtherosclerosis and Cardiovascular Diseases

Cited by 48

Single-cell transcriptomic analysis uncovers diverse and dynamic senescent cell populations

Wechter, N., Rossi, M., Anerillas, C., Tsitsipatis, D., Piao, Y., Fan, J., Martindale, J. L., De, S., Mazan-Mamczarz, K., & Gorospe, M. (2023) · Aging

Telomeres, Telomerase, and SenescenceSingle-cell and spatial transcriptomics

Cited by 43

A BDNF-TrkB autocrine loop enhances senescent cell viability

Anerillas, C., Herman, A. B., Munk, R., Garrido, A., Lam, K.-W. G., Payea, M. J., Rossi, M., Tsitsipatis, D., Martindale, J. L., Piao, Y., et al. (2022) · Nature Communications

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 35

Reduced endosomal microautophagy activity in aging associates with enhanced exocyst‐mediated protein secretion

Krause, G. J., Diaz, A., Jafari, M., Khawaja, R. R., Agullo‐Pascual, E., Santiago‐Fernández, O., Richards, A. L., Chen, K., Dmitriev, P., Sun, Y., et al. (2022) · Aging Cell

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 35

Reduction of lamin B receptor levels by miR-340-5p disrupts chromatin, promotes cell senescence and enhances senolysis

Herman, A. B., Anerillas, C., Harris, S. C., Munk, R., Martindale, J. L., Yang, X., Mazan-Mamczarz, K., Zhang, Y., Heckenbach, I. J., Scheibye-Knudsen, M., et al. (2021) · Nucleic Acids Research

Telomeres, Telomerase, and SenescenceMicroRNA in disease regulation

Cited by 31

α 4 Coordinates Small Intestinal Epithelium Homeostasis by Regulating Stability of HuR

Chung, H. K., Wang, S. R., Xiao, L., Rathor, N., Turner, D. J., Yang, P., Gorospe, M., Rao, J. N., & Wang, J.-Y. (2018) · Molecular and Cellular Biology

RNA Research and SplicingDigestive system and related health

Cited by 26

MAPKs in the early steps of senescence implemEMTation

Anerillas, C., Altés, G., & Gorospe, M. (2023) · Frontiers in Cell and Developmental Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 13

SenCat: Cataloging human cell senescence through multi-omic profiling of multiple senescent primary cell types

Anerillas, C., Altés, G., Gresova, K., Tsitsipatis, D., Mazan-Mamczarz, K., Banarjee, R., Cunningham, A. S. G., Salamini-Montemurri, M., Yang, J.-H., Munk, R., et al. (2026) · Molecular Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 11

Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation

Oksanen, M., Mastropasqua, F., Mazan-Mamczarz, K., Martindale, J. L., Ye, X., Arora, A., Banskota, N., Gorospe, M., & Tammimies, K. (2026) · Nucleic Acids Research

Genetics and Neurodevelopmental DisordersRNA Research and Splicing

Cited by 7

Circulating Cell Type Senescence Signatures Reveal High-Resolution Health Status and Trajectories in Human Longitudinal Studies

Olinger, B., Anerillas, C., Herman, A. B., Tsitsipatis, D., Banarjee, R., Tanaka, T., Candia, J., Maragkakis, M., Bandinelli, S., Walker, K. A., et al. (2026) · medRxiv

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 0