Wu, Hong

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

Wang, S., Gao, J., Lei, Q., Rozengurt, N., Pritchard, C., Jiao, J., Thomas, G. V., Li, G., Roy-Burman, P., Nelson, P. S., et al. (2003) · Cancer Cell

Prostate Cancer Treatment and ResearchPI3K/AKT/mTOR signaling in cancer

Cited by 1,109

Essential role for nuclear PTEN in maintaining chromosomal integrity

Shen, W. H., Balajee, A. S., Wang, J., Wu, H., Eng, C., Pandolfi, P. P., & Yin, Y. (2007) · Cell

DNA Repair MechanismsMicrotubule and mitosis dynamics

Cited by 979

A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2

Schlacher, K., Wu, H., & Jasin, M. (2012) · Cancer Cell

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 936

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

Zhang, J., Grindley, J. C., Yin, T., Jayasinghe, S., He, X. C., Ross, J. T., Haug, J. S., Rupp, D., Porter-Westpfahl, K. S., Wiedemann, L. M., et al. (2006) · Nature

Hematopoietic Stem Cell TransplantationPI3K/AKT/mTOR signaling in cancer

Cited by 817

Negative Regulation of Neural Stem/Progenitor Cell Proliferation by the Pten Tumor Suppressor Gene in Vivo

Groszer, M., Erickson, R., Scripture-Adams, D. D., Lesche, R., Trumpp, A., Zack, J. A., Kornblum, H. I., Liu, X., & Wu, H. (2001) · Science

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 798

Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

Le Belle, J. E., Orozco, N. M., Paucar, A. A., Saxe, J. P., Mottahedeh, J., Pyle, A. D., Wu, H., & Kornblum, H. I. (2011) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsRedox biology and oxidative stress

Cited by 789

Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development

Liu, X., Wu, H., Byrne, M., Krane, S., & Jaenisch, R. (1997) · Proceedings of the National Academy of Sciences

Connective tissue disorders researchCollagen: Extraction and Characterization

Cited by 614

Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity

Stiles, B., Wang, Y., Stahl, A., Bassilian, S., Lee, W. P., Kim, Y.-J., Sherwin, R., Devaskar, S., Lesche, R., Magnuson, M. A., et al. (2004) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerLiver Disease Diagnosis and Treatment

Cited by 436

Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy

Pope, W. B., Prins, R. M., Albert Thomas, M., Nagarajan, R., Yen, K. E., Bittinger, M. A., Salamon, N., Chou, A. P., Yong, W. H., Soto, H., et al. (2012) · Journal of Neuro-Oncology

Glioma Diagnosis and TreatmentAdvanced MRI Techniques and Applications

Cited by 318

PTEN negatively regulates neural stem cell self-renewal by modulating G 0 -G 1 cell cycle entry

Groszer, M., Erickson, R., Scripture-Adams, D. D., Dougherty, J. D., Le Belle, J., Zack, J. A., Geschwind, D. H., Liu, X., Kornblum, H. I., & Wu, H. (2006) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsGlioma Diagnosis and Treatment

Cited by 306

Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland

Li, G., Robinson, G. W., Lesche, R., Martinez-Diaz, H., Jiang, Z., Rozengurt, N., Wagner, K.-U., Wu, D.-C., Lane, T. F., Liu, X., et al. (2002) · Development

PI3K/AKT/mTOR signaling in cancerDevelopmental Biology and Gene Regulation

Cited by 272

PTENless means more

Stiles, B., Groszer, M., Wang, S., Jiao, J., & Wu, H. (2004) · Developmental Biology

PI3K/AKT/mTOR signaling in cancerDevelopmental Biology and Gene Regulation

Cited by 230

Enhanced Paracrine FGF10 Expression Promotes Formation of Multifocal Prostate Adenocarcinoma and an Increase in Epithelial Androgen Receptor

Memarzadeh, S., Xin, L., Mulholland, D. J., Mansukhani, A., Wu, H., Teitell, M. A., & Witte, O. N. (2007) · Cancer Cell

Prostate Cancer Treatment and ResearchFibroblast Growth Factor Research

Cited by 201

Hydrophobic surfaces for enhanced differentiation of embryonic stem cell-derived embryoid bodies

Valamehr, B., Jonas, S. J., Polleux, J., Qiao, R., Guo, S., Gschweng, E. H., Stiles, B., Kam, K., Luo, T.-J. M., Witte, O. N., et al. (2008) · Proceedings of the National Academy of Sciences

Pluripotent Stem Cells ResearchCellular Mechanics and Interactions

Cited by 155

PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression

Chang, C.-J., Mulholland, D. J., Valamehr, B., Mosessian, S., Sellers, W. R., & Wu, H. (2008) · Molecular and Cellular Biology

PI3K/AKT/mTOR signaling in cancerCancer-related Molecular Pathways

Cited by 155

PTEN in Regulating Hematopoiesis and Leukemogenesis

Wu, Y., Zhu, H., & Wu, H. (2020) · Cold Spring Harbor Perspectives in Medicine

PI3K/AKT/mTOR signaling in cancerAcute Lymphoblastic Leukemia research

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