Palczewski, Krzysztof

The Molecular Basis of Retinoid Absorption

Wongsiriroj, N., Piantedosi, R., Palczewski, K., Goldberg, I. J., Johnston, T. P., Li, E., & Blaner, W. S. (2008) · Journal of Biological Chemistry

Retinoids in leukemia and cellular processesCholesterol and Lipid Metabolism

Cited by 126

The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision

von Lintig, J., Kiser, P. D., Golczak, M., & Palczewski, K. (2010) · Trends in Biochemical Sciences

Retinoids in leukemia and cellular processesPhotoreceptor and optogenetics research

Cited by 119

Visual Rhodopsin Sees the Light: Structure and Mechanism of G Protein Signaling

Ridge, K. D., & Palczewski, K. (2007) · Journal of Biological Chemistry

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 113

Ligand Channeling within a G-protein-coupled Receptor

Schädel, S. A., Heck, M., Maretzki, D., Filipek, S., Teller, D. C., Palczewski, K., & Hofmann, K. P. (2003) · Journal of Biological Chemistry

Photoreceptor and optogenetics researchReceptor Mechanisms and Signaling

Cited by 111

Retinoids for treatment of retinal diseases

Palczewski, K. (2010) · Trends in Pharmacological Sciences

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 111

Retinoids and Retinal Diseases

Kiser, P. D., & Palczewski, K. (2016) · Annual Review of Vision Science

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 108

Vertebrate Membrane Proteins: Structure, Function, and Insights from Biophysical Approaches

Müller, D. J., Wu, N., & Palczewski, K. (2008) · Pharmacological Reviews

Lipid Membrane Structure and BehaviorProtein Structure and Dynamics

Cited by 104

Identification of All-trans-Retinol:All-trans-13,14-dihydroretinol Saturase

Moise, A. R., Kuksa, V., Imanishi, Y., & Palczewski, K. (2004) · Journal of Biological Chemistry

Retinoids in leukemia and cellular processesPlant biochemistry and biosynthesis

Cited by 103

Retinosomes

Imanishi, Y., Gerke, V., & Palczewski, K. (2004) · The Journal of Cell Biology

Lipid metabolism and biosynthesisCellular transport and secretion

Cited by 102

Trafficking of Membrane-Associated Proteins to Cone Photoreceptor Outer Segments Requires the Chromophore 11- cis -Retinal

Zhang, H., Fan, J., Li, S., Karan, S., Rohrer, B., Palczewski, K., Frederick, J. M., Crouch, R. K., & Baehr, W. (2008) · The Journal of Neuroscience

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 101

Isomerization of all-trans-Retinol to cis-Retinols in Bovine Retinal Pigment Epithelial Cells: Dependence on the Specificity of Retinoid-Binding Proteins

McBee, J. K., Kuksa, V., Alvarez, R., de Lera, A. R., Prezhdo, O., Haeseleer, F., Sokal, I., & Palczewski, K. (2000) · Biochemistry

Retinoids in leukemia and cellular processesPhotoreceptor and optogenetics research

Cited by 95

Metabolic Basis of Visual Cycle Inhibition by Retinoid and Nonretinoid Compounds in the Vertebrate Retina

Golczak, M., Maeda, A., Bereta, G., Maeda, T., Kiser, P. D., Hunzelmann, S., von Lintig, J., Blaner, W. S., & Palczewski, K. (2008) · Journal of Biological Chemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 93

Lecithin:Retinol Acyltransferase Is Critical for Cellular Uptake of Vitamin A from Serum Retinol-binding Protein

Amengual, J., Golczak, M., Palczewski, K., & von Lintig, J. (2012) · Journal of Biological Chemistry

Retinoids in leukemia and cellular processesRetinal Development and Disorders

Cited by 93

Delivery of retinoid-based therapies to target tissues

Moise, A. R., Noy, N., Palczewski, K., & Blaner, W. S. (2007) · Biochemistry

Retinoids in leukemia and cellular processesDrug Transport and Resistance Mechanisms

Cited by 93

Retinyl Ester Storage Particles (Retinosomes) from the Retinal Pigmented Epithelium Resemble Lipid Droplets in Other Tissues

Orban, T., Palczewska, G., & Palczewski, K. (2011) · Journal of Biological Chemistry

Lipid metabolism and biosynthesisRetinoids in leukemia and cellular processes

Cited by 89

Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes

Palczewska, G., Maeda, T., Imanishi, Y., Sun, W., Chen, Y., Williams, D. R., Piston, D. W., Maeda, A., & Palczewski, K. (2010) · Nature Medicine

Retinal Development and DisordersAdvanced Fluorescence Microscopy Techniques

Cited by 88

Retinyl Ester Formation by Lecithin:Retinol Acyltransferase Is a Key Regulator of Retinoid Homeostasis in Mouse Embryogenesis

Kim, Y.-K., Wassef, L., Hamberger, L., Piantedosi, R., Palczewski, K., Blaner, W. S., & Quadro, L. (2008) · Journal of Biological Chemistry

Retinoids in leukemia and cellular processesRetinal Development and Disorders

Cited by 80

Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins

Golczak, M., Kiser, P. D., Sears, A. E., Lodowski, D. T., Blaner, W. S., & Palczewski, K. (2012) · Journal of Biological Chemistry

Enzyme Structure and FunctionLipid metabolism and biosynthesis

Cited by 77

Evaluation of the role of the retinal G protein‐coupled receptor (RGR) in the vertebrate retina in vivo

Maeda, T., Van Hooser, J. P., Driessen, C. A. G. G., Filipek, S., Janssen, J. J. M., & Palczewski, K. (2003) · Journal of Neurochemistry

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 75

Molecular pharmacodynamics of emixustat in protection against retinal degeneration

Zhang, J., Kiser, P. D., Badiee, M., Palczewska, G., Dong, Z., Golczak, M., Tochtrop, G. P., & Palczewski, K. (2015) · Journal of Clinical Investigation

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 75

Conformational Dynamics of Activation for the Pentameric Complex of Dimeric G Protein-Coupled Receptor and Heterotrimeric G Protein

Orban, T., Jastrzebska, B., Gupta, S., Wang, B., Miyagi, M., Chance, M. R., & Palczewski, K. (2012) · Structure

Receptor Mechanisms and SignalingMass Spectrometry Techniques and Applications

Cited by 67

Asymmetry of the rhodopsin dimer in complex with transducin

Jastrzebska, B., Orban, T., Golczak, M., Engel, A., & Palczewski, K. (2013) · The FASEB Journal

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 66

A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration

Chen, Y., Chen, Y., Jastrzebska, B., Golczak, M., Gulati, S., Tang, H., Seibel, W., Li, X., Jin, H., Han, Y., et al. (2018) · Nature Communications

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 64

Retinoid cycle in the vertebrate retina: experimental approaches and mechanisms of isomerization

Kuksa, V., Imanishi, Y., Batten, M., Palczewski, K., & Moise, A. R. (2003) · Vision Research

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 64