Palczewski, Krzysztof

Differential modulation of Cav2.1 channels by calmodulin and Ca2+-binding protein 1

Lee, A., Westenbroek, R. E., Haeseleer, F., Palczewski, K., Scheuer, T., & Catterall, W. A. (2002) · Nature Neuroscience

Ion channel regulation and functionNeuroscience and Neuropharmacology Research

Cited by 200

Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye

Imanishi, Y., Batten, M. L., Piston, D. W., Baehr, W., & Palczewski, K. (2004) · The Journal of Cell Biology

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 194

RBP4 disrupts Vitamin A uptake homeostasis in a STRA6-deficient animal model for Matthew-Wood syndrome

Isken, A., Golczak, M., Oberhauser, V., Hunzelmann, S., Driever, W., Imanishi, Y., Palczewski, K., & von Lintig, J. (2008) · Cell Metabolism

Retinoids in leukemia and cellular processesRetinal Development and Disorders

Cited by 194

ABCA4 disease progression and a proposed strategy for gene therapy

Cideciyan, A. V., Swider, M., Aleman, T. S., Tsybovsky, Y., Schwartz, S. B., Windsor, E. A. M., Roman, A. J., Sumaroka, A., Steinberg, J. D., Jacobson, S. G., et al. (2009) · Human Molecular Genetics

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 186

Molecular Characterization of a Novel Short-chain Dehydrogenase/Reductase That Reduces All-trans-retinal

Haeseleer, F., Huang, J., Lebioda, L., Saari, J. C., & Palczewski, K. (1998) · Journal of Biological Chemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 184

Key enzymes of the retinoid (visual) cycle in vertebrate retina

Kiser, P. D., Golczak, M., Maeda, A., & Palczewski, K. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 177

Phototransduction: crystal clear

Ridge, K. D., Abdulaev, N. G., Sousa, M., & Palczewski, K. (2003) · Trends in Biochemical Sciences

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 163

Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo

Maeda, A., Maeda, T., Imanishi, Y., Kuksa, V., Alekseev, A., Bronson, J. D., Zhang, H., Zhu, L., Sun, W., Saperstein, D. A., et al. (2005) · Journal of Biological Chemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 159

Crystal structure of native RPE65, the retinoid isomerase of the visual cycle

Kiser, P. D., Golczak, M., Lodowski, D. T., Chance, M. R., & Palczewski, K. (2009) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 158

Rhodopsin Signaling and Organization in Heterozygote Rhodopsin Knockout Mice

Liang, Y., Fotiadis, D., Maeda, T., Maeda, A., Modzelewska, A., Filipek, S., Saperstein, D. A., Engel, A., & Palczewski, K. (2004) · Journal of Biological Chemistry

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 157

Recovery of Visual Functions in a Mouse Model of Leber Congenital Amaurosis

Van Hooser, J. P., Liang, Y., Maeda, T., Kuksa, V., Jang, G.-F., He, Y.-G., Rieke, F., Fong, H. K. W., Detwiler, P. B., & Palczewski, K. (2002) · Journal of Biological Chemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 154

Related enzymes solve evolutionarily recurrent problems in the metabolism of carotenoids

MOISE, A., VONLINTIG, J., & PALCZEWSKI, K. (2005) · Trends in Plant Science

Plant biochemistry and biosynthesisRetinoids in leukemia and cellular processes

Cited by 153

Structural basis of carotenoid cleavage: From bacteria to mammals

Sui, X., Kiser, P. D., Lintig, J. V., & Palczewski, K. (2013) · Archives of Biochemistry and Biophysics

Metal-Catalyzed Oxygenation MechanismsEnzyme Structure and Function

Cited by 139

Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1

Mast, N., Annalora, A. J., Lodowski, D. T., Palczewski, K., Stout, C. D., & Pikuleva, I. A. (2011) · Journal of Biological Chemistry

Metal-Catalyzed Oxygenation MechanismsSteroid Chemistry and Biochemistry

Cited by 138

The Crystallographic Model of Rhodopsin and Its Use in Studies of Other G Protein–Coupled Receptors

Filipek, S., Teller, D. C., Palczewski, K., & Stenkamp, R. (2003) · Annual Review of Biophysics and Biomolecular Structure

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 137

Primary amines protect against retinal degeneration in mouse models of retinopathies

Maeda, A., Golczak, M., Chen, Y., Okano, K., Kohno, H., Shiose, S., Ishikawa, K., Harte, W., Palczewska, G., Maeda, T., et al. (2012) · Nature Chemical Biology

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 135

Functional Characterization of Rhodopsin Monomers and Dimers in Detergents

Jastrzebska, B., Maeda, T., Zhu, L., Fotiadis, D., Filipek, S., Engel, A., Stenkamp, R. E., & Palczewski, K. (2004) · Journal of Biological Chemistry

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 134

Pharmacological and rAAV Gene Therapy Rescue of Visual Functions in a Blind Mouse Model of Leber Congenital Amaurosis

Batten, M. L., Imanishi, Y., Tu, D. C., Doan, T., Zhu, L., Pang, J., Glushakova, L., Moise, A. R., Baehr, W., Van Gelder, R. N., et al. (2005) · PLoS Medicine

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 134

Preferential Release of 11-cis-retinol from Retinal Pigment Epithelial Cells in the Presence of Cellular Retinaldehyde-binding Protein

Stecher, H., Gelb, M. H., Saari, J. C., & Palczewski, K. (1999) · Journal of Biological Chemistry

Retinoids in leukemia and cellular processesRetinal Development and Disorders

Cited by 134

STRA6 is critical for cellular Vitamin A uptake and homeostasis

Amengual, J., Zhang, N., Kemerer, M., Maeda, T., Palczewski, K., & Von Lintig, J. (2014) · Human Molecular Genetics

Retinoids in leukemia and cellular processesRetinal Development and Disorders

Cited by 134

Disruption of the 11- cis -Retinol Dehydrogenase Gene Leads to Accumulation of cis -Retinols and cis -Retinyl Esters

Driessen, C. A. G. G., Winkens, H. J., Hoffmann, K., Kuhlmann, L. D., Janssen, B. P. M., Van Vugt, A. H. M., Van Hooser, J. P., Wieringa, B. E., Deutman, A. F., Palczewski, K., et al. (2000) · Molecular and Cellular Biology

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 132

Activation of G Protein–Coupled Receptors: Beyond Two-State Models and Tertiary Conformational Changes

Park, P. S.-H., Lodowski, D. T., & Palczewski, K. (2008) · Annual Review of Pharmacology and Toxicology

Receptor Mechanisms and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 131

Redundant and unique roles of retinol dehydrogenases in the mouse retina

Maeda, A., Maeda, T., Sun, W., Zhang, H., Baehr, W., & Palczewski, K. (2007) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 131

Crystal structure of rhodopsin: a template for cone visual pigments and other G protein-coupled receptors

Stenkamp, R. E., Filipek, S., Driessen, C. A. G. G., Teller, D. C., & Palczewski, K. (2002) · Biochimica et Biophysica Acta (BBA) - Biomembranes

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 128