Coffey, Robert J.

Reassessment of exosome composition

Jeppesen, D. K., Fenix, A. M., Franklin, J. L., Higginbotham, J. N., Zhang, Q., Zimmerman, L. J., Liebler, D. C., Ping, J., Liu, Q., Evans, R., et al. (2019) · Cell

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 2,975

Proteogenomic characterization of human colon and rectal cancer

CPTAC, T. N., Zhang, B., Wang, J., Wang, X., Zhu, J., Liu, Q., Shi, Z., Chambers, M. C., Zimmerman, L. J., Shaddox, K. F., et al. (2014) · Nature

Cancer Genomics and DiagnosticsAdvanced Proteomics Techniques and Applications

Cited by 1,462

Extracellular Vesicles and Nanoparticles: Emerging Complexities

Jeppesen, D. K., Zhang, Q., Franklin, J. L., & Coffey, R. J. (2023) · Trends in Cell Biology

Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery

Cited by 705

The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor

Powell, A. E., Wang, Y., Li, Y., Poulin, E. J., Means, A. L., Washington, M. K., Higginbotham, J. N., Juchheim, A., Prasad, N., Levy, S. E., et al. (2012) · Cell

Cancer Cells and MetastasisDigestive system and related health

Cited by 694

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models

Schulte, M. L., Fu, A., Zhao, P., Li, J., Geng, L., Smith, S. T., Kondo, J., Coffey, R. J., Johnson, M. O., Rathmell, J. C., et al. (2018) · Nature Medicine

Amino Acid Enzymes and MetabolismCancer, Hypoxia, and Metabolism

Cited by 494

lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

Lu, Y., Zhao, X., Liu, Q., Li, C., Graves-Deal, R., Cao, Z., Singh, B., Franklin, J. L., Wang, J., Hu, H., et al. (2017) · Nature Medicine

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 425

Amphiregulin exosomes increase cancer cell invasion

Higginbotham, J. N., Demory Beckler, M., Gephart, J. D., Franklin, J. L., Bogatcheva, G., Kremers, G.-J., Piston, D. W., Ayers, G. D., McConnell, R. E., Tyska, M. J., et al. (2011) · Current Biology

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 360

Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates

Means, A. L., Meszoely, I. M., Suzuki, K., Miyamoto, Y., Rustgi, A. K., Coffey, R. J., Wright, C. V. E., Stoffers, D. A., & Leach, S. D. (2005) · Development

Pancreatic and Hepatic Oncology ResearchPancreatic function and diabetes

Cited by 344

The enterocyte microvillus is a vesicle-generating organelle

McConnell, R. E., Higginbotham, J. N., Shifrin, D. A., Tabb, D. L., Coffey, R. J., & Tyska, M. J. (2009) · Journal of Cell Biology

Cellular transport and secretionExtracellular vesicles in disease

Cited by 260

Deep Brain Stimulation Devices: A Brief Technical History and Review

Coffey, R. J. (2009) · Artificial Organs

Deep Brain Stimulation and Movement DisordersObsessive-Compulsive Spectrum Disorders

Cited by 178

Synergistic Interaction of the Neu Proto-Oncogene Product and Transforming Growth Factor α in the Mammary Epithelium of Transgenic Mice

Muller, W. J., Arteaga, C. L., Muthuswamy, S. K., Siegel, P. M., Webster, M. A., Cardiff, R. D., Meise, K. S., Li, F., Halter, S. A., & Coffey, R. J. (1996) · Molecular and Cellular Biology

HER2/EGFR in Cancer ResearchEstrogen and related hormone effects

Cited by 147

Lrp6 is required for convergent extension during Xenopus gastrulation

Tahinci, E., Thorne, C. A., Franklin, J. L., Salic, A., Christian, K. M., Lee, L. A., Coffey, R. J., & Lee, E. (2007) · Development

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 73

Resistance to EGFR-Targeted Therapy: A Family Affair

Vlacich, G., & Coffey, R. J. (2011) · Cancer Cell

HER2/EGFR in Cancer ResearchLung Cancer Treatments and Mutations

Cited by 61

Combined blockade of EGFR and glutamine metabolism in preclinical models of colorectal cancer

Cohen, A. S., Geng, L., Zhao, P., Fu, A., Schulte, M. L., Graves-Deal, R., Washington, M. K., Berlin, J., Coffey, R. J., & Manning, H. C. (2020) · Translational Oncology

Colorectal Cancer Treatments and StudiesCancer, Hypoxia, and Metabolism

Cited by 49

Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans

Kawasaki, K., Freimuth, J., Meyer, D. S., Lee, M. M., Tochimoto-Okamoto, A., Benzinou, M., Clermont, F. F., Wu, G., Roy, R., Letteboer, T. G. W., et al. (2014) · Proceedings of the National Academy of Sciences

TGF-β signaling in diseasesVascular Anomalies and Treatments

Cited by 47

Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer

Li, C., Singh, B., Graves-Deal, R., Ma, H., Starchenko, A., Fry, W. H., Lu, Y., Wang, Y., Bogatcheva, G., Khan, M. P., et al. (2017) · Proceedings of the National Academy of Sciences

Colorectal Cancer Treatments and StudiesCancer Cells and Metastasis

Cited by 47

Effects of trastuzumab on epidermal growth factor receptor‐dependent and ‐independent human colon cancer cells

Kuwada, S. K., Scaife, C. L., Kuang, J., Li, X., Wong, R. F., Florell, S. R., Coffey, R. J., & Gray, P. D. (2004) · International Journal of Cancer

HER2/EGFR in Cancer ResearchColorectal Cancer Treatments and Studies

Cited by 41

Loss of Lrig1 Leads to Expansion of Brunner Glands Followed by Duodenal Adenomas with Gastric Metaplasia

Wang, Y., Shi, C., Lu, Y., Poulin, E. J., Franklin, J. L., & Coffey, R. J. (2015) · The American Journal of Pathology

HER2/EGFR in Cancer ResearchDigestive system and related health

Cited by 26

Expression of LRIG1, a Negative Regulator of EGFR, Is Dynamically Altered during Different Stages of Gastric Carcinogenesis

Yu, S., Yang, M., Lim, K.-M., Cho, Y., Kim, H., Lee, K., Jeong, S.-H., Coffey, R. J., Goldenring, J. R., & Nam, K. T. (2018) · The American Journal of Pathology

Gastric Cancer Management and OutcomesHER2/EGFR in Cancer Research

Cited by 19