Frey, William H.

Intranasal delivery to the central nervous system: Mechanisms and experimental considerations

Dhuria, S. V., Hanson, L. R., & Frey, W. H. (2010) · Journal of Pharmaceutical Sciences

Advanced Drug Delivery SystemsInhalation and Respiratory Drug Delivery

Cited by 1,239

Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration

Thorne, R. G., Pronk, G. J., Padmanabhan, V., & Frey, W. H. (2004) · Neuroscience

Advanced Drug Delivery SystemsBarrier Structure and Function Studies

Cited by 958

Delivery of Neurotrophic Factors to the Central Nervous System: Pharmacokinetic Considerations

Thorne, R. G., & Frey, W. H. (2001) · Clinical Pharmacokinetics

Barrier Structure and Function StudiesAdvanced Drug Delivery Systems

Cited by 487

Quantitative analysis of the olfactory pathway for drug delivery to the brain

Thorne, R. G., Emory, C. R., Ala, T. A., & Frey, W. H. (1995) · Brain Research

Advanced Drug Delivery SystemsOlfactory and Sensory Function Studies

Cited by 352

Intranasal Treatment of Central Nervous System Dysfunction in Humans

Chapman, C. D., Frey, W. H., Craft, S., Danielyan, L., Hallschmid, M., Schiöth, H. B., & Benedict, C. (2013) · Pharmaceutical Research

Advanced Drug Delivery SystemsInhalation and Respiratory Drug Delivery

Cited by 310

Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimer’s disease

Atamna, H., & Frey, W. H. (2007) · Mitochondrion

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 278

Intranasal administration of interferon beta bypasses the blood–brain barrier to target the central nervous system and cervical lymph nodes: a non-invasive treatment strategy for multiple sclerosis

Ross, T. M., Martinez, P. M., Renner, J. C., Thorne, R. G., Hanson, L. R., & Frey, W. H. (2004) · Journal of Neuroimmunology

Advanced Drug Delivery SystemsMultiple Sclerosis Research Studies

Cited by 242

Chlamydophila (Chlamydia) pneumoniae in the Alzheimer's brain

Gérard, H. C., Dreses-Werringloer, U., Wildt, K. S., Deka, S., Oszust, C., Balin, B. J., Frey, W. H., Bordayo, E. Z., Whittum-Hudson, J. A., & Hudson, A. P. (2006) · FEMS Immunology & Medical Microbiology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 186

Intranasal delivery of insulin via the olfactory nerve pathway

Renner, D. B., Svitak, A. L., Gallus, N. J., Ericson, M. E., Frey, W. H., & Hanson, L. R. (2012) · Journal of Pharmacy and Pharmacology

Advanced Drug Delivery SystemsOlfactory and Sensory Function Studies

Cited by 116

Intranasal Adeno-Associated Virus Mediated Gene Delivery and Expression of Human Iduronidase in the Central Nervous System: A Noninvasive and Effective Approach for Prevention of Neurologic Disease in Mucopolysaccharidosis Type I

Belur, L. R., Temme, A., Podetz-Pedersen, K. M., Riedl, M., Vulchanova, L., Robinson, N., Hanson, L. R., Kozarsky, K. F., Orchard, P. J., Frey, W. H., et al. (2017) · Human Gene Therapy

Lysosomal Storage Disorders ResearchVirus-based gene therapy research

Cited by 67

Intranasal delivery of siRNA to the olfactory bulbs of mice via the olfactory nerve pathway

Renner, D. B., Frey, W. H., & Hanson, L. R. (2012) · Neuroscience Letters

RNA Interference and Gene DeliveryAdvanced Drug Delivery Systems

Cited by 62