Georgiou, George

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

Wang, W., Green, M., Choi, J. E., Gijón, M., Kennedy, P. D., Johnson, J. K., Liao, P., Lang, X., Kryczek, I., Sell, A., et al. (2019) · Nature

Ferroptosis and cancer prognosisCancer Immunotherapy and Biomarkers

Cited by 2,880

Cysteine depletion induces pancreatic tumor ferroptosis in mice

Badgley, M. A., Kremer, D. M., Maurer, H. C., DelGiorno, K. E., Lee, H.-J., Purohit, V., Sagalovskiy, I. R., Ma, A., Kapilian, J., Firl, C. E. M., et al. (2020) · Science

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 1,294

The promise and challenge of high-throughput sequencing of the antibody repertoire

Georgiou, G., Ippolito, G. C., Beausang, J., Busse, C. E., Wardemann, H., & Quake, S. R. (2014) · Nature Biotechnology

Monoclonal and Polyclonal Antibodies ResearchT-cell and B-cell Immunology

Cited by 652

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

DeKosky, B. J., Ippolito, G. C., Deschner, R. P., Lavinder, J. J., Wine, Y., Rawlings, B. M., Varadarajan, N., Giesecke, C., Dörner, T., Andrews, S. F., et al. (2013) · Nature Biotechnology

T-cell and B-cell ImmunologyMonoclonal and Polyclonal Antibodies Research

Cited by 410

Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme

Triplett, T. A., Garrison, K. C., Marshall, N., Donkor, M., Blazeck, J., Lamb, C., Qerqez, A., Dekker, J. D., Tanno, Y., Lu, W.-C., et al. (2018) · Nature Biotechnology

Cancer Immunotherapy and BiomarkersTryptophan and brain disorders

Cited by 321

Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells

Reddy, S. T., Ge, X., Miklos, A. E., Hughes, R. A., Kang, S. H., Hoi, K. H., Chrysostomou, C., Hunicke-Smith, S. P., Iverson, B. L., Tucker, P. W., et al. (2010) · Nature Biotechnology

Monoclonal and Polyclonal Antibodies ResearchT-cell and B-cell Immunology

Cited by 292

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

Saphire, E. O., Schendel, S. L., Fusco, M. L., Gangavarapu, K., Gunn, B. M., Wec, A. Z., Halfmann, P. J., Brannan, J. M., Herbert, A. S., Qiu, X., et al. (2018) · Cell

Viral Infections and Outbreaks ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 212

Production of correctly folded Fab antibody fragment in the cytoplasm of Escherichia coli trxB gor mutants via the coexpression of molecular chaperones

Levy, R., Weiss, R., Chen, G., Iverson, B. L., & Georgiou, G. (2001) · Protein Expression and Purification

Protein purification and stabilityHeat shock proteins research

Cited by 207

Improving Antibody Therapeutics by Manipulating the Fc Domain: Immunological and Structural Considerations

Delidakis, G., Kim, J. E., George, K., & Georgiou, G. (2022) · Annual Review of Biomedical Engineering

Monoclonal and Polyclonal Antibodies ResearchT-cell and B-cell Immunology

Cited by 87

Recursive genomewide recombination and sequencing reveals a key refinement step in the evolution of a metabolic innovation in Escherichia coli

Quandt, E. M., Deatherage, D. E., Ellington, A. D., Georgiou, G., & Barrick, J. E. (2014) · Proceedings of the National Academy of Sciences

Evolution and Genetic DynamicsMicrobial Metabolic Engineering and Bioproduction

Cited by 78

Continuous production of the lipopeptide biosurfactant of Bacillus licheniformis JF-2

Lin, S. C., Carswell, K. S., Sharma, M. M., & Georgiou, G. (1994) · Applied Microbiology and Biotechnology

Microbial bioremediation and biosurfactantsSurfactants and Colloidal Systems

Cited by 64