Melum, Espen

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

Huang, Y.-H., Zhu, C., Kondo, Y., Anderson, A. C., Gandhi, A., Russell, A., Dougan, S. K., Petersen, B.-S., Melum, E., Pertel, T., et al. (2015) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 717

Cholangiocyte organoids can repair bile ducts after transplantation in the human liver

Sampaziotis, F., Muraro, D., Tysoe, O. C., Sawiak, S., Beach, T. E., Godfrey, E. M., Upponi, S. S., Brevini, T., Wesley, B. T., Garcia-Bernardo, J., et al. (2021) · Science

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 394

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

The UK-PSCSC Consortium, Liu, J. Z., The International IBD Genetics Consortium, The International PSC Study Group, Hov, J. R., Folseraas, T., Ellinghaus, E., Rushbrook, S. M., Doncheva, N. T., Andreassen, O. A., et al. (2013) · Nature Genetics

Liver Diseases and ImmunityGenetic Associations and Epidemiology

Cited by 391

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

The UK-PSC Consortium, Ji, S.-G., The International IBD Genetics Consortium, The International PSC Study Group, Juran, B. D., Mucha, S., Folseraas, T., Jostins, L., Melum, E., Kumasaka, N., et al. (2017) · Nature Genetics

Liver Diseases and ImmunityGenetic Associations and Epidemiology

Cited by 357

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids

Sampaziotis, F., Justin, A. W., Tysoe, O. C., Sawiak, S., Godfrey, E. M., Upponi, S. S., Gieseck, R. L., de Brito, M. C., Berntsen, N. L., Gómez-Vázquez, M. J., et al. (2017) · Nature Medicine

Tissue Engineering and Regenerative MedicinePediatric Hepatobiliary Diseases and Treatments

Cited by 296

Scalable production of tissue-like vascularized liver organoids from human PSCs

Harrison, S. P., Siller, R., Tanaka, Y., Chollet, M. E., de la Morena-Barrio, M. E., Xiang, Y., Patterson, B., Andersen, E., Bravo-Pérez, C., Kempf, H., et al. (2023) · Experimental & Molecular Medicine

Pluripotent Stem Cells Research3D Printing in Biomedical Research

Cited by 119

Liver transplantation in the Nordic countries - an intention to treat and post-transplant analysis from The Nordic Liver Transplant Registry 1982-2013

Fosby, B., Melum, E., Bjøro, K., Bennet, W., Rasmussen, A., Andersen, I. M., Castedal, M., Olausson, M., Wibeck, C., Gotlieb, M., et al. (2015) · Scandinavian Journal of Gastroenterology

Organ Transplantation Techniques and OutcomesTransplantation: Methods and Outcomes

Cited by 99

Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis

Chung, B. K., Øgaard, J., Reims, H. M., Karlsen, T. H., & Melum, E. (2022) · Hepatology Communications

Single-cell and spatial transcriptomicsLiver physiology and pathology

Cited by 85

Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease

Næss, S., Björnsson, E., Anmarkrud, J. A., Mamari, S. A., Juran, B. D., Lazaridis, K. N., Chapman, R., Bergquist, A., Melum, E., Marsh, S. G. E., et al. (2014) · Liver International

Liver Diseases and ImmunityInflammatory Bowel Disease

Cited by 54

Indications and outcomes in liver transplantation in patients with primary sclerosing cholangitis in Norway

Andersen, I. M., Fosby, B., Boberg, K. M., Clausen, O. P. F., Jebsen, P., Melum, E., Line, P. D., Foss, A., Schrumpf, E., & Karlsen, T. H. (2015) · Transplantation Direct

Liver Diseases and ImmunityOrgan Transplantation Techniques and Outcomes

Cited by 45

Single-Cell Transcriptomic Profiling of Cholangiocyte Organoids Derived from Bile Ducts of Primary Sclerosing Cholangitis Patients

Frank, A. K., Chung, B. K., De Novales, M. L. L., Engesæter, L. K., Hoyle, H. W., Øgaard, J., Heslop, J., Karlsen, T. H., Tysoe, O., Brevini, T., et al. (2024) · Digestive Diseases and Sciences

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 14

Developing Multi-Agent LLM Applications Through Continuous Human-LLM Co-Programming

Song, H., Goknil, A., Jiang, X., Melum, E., Joe, H., Gazzotti, C., Frascolla, V., Videsjorden, A. N., & Nguyen, P. (2025) · 2025 IEEE/ACM 4th International Conference on AI Engineering – Software Engineering for AI (CAIN)

Software Engineering ResearchSoftware Engineering Techniques and Practices

Cited by 3