Bottiglieri, Teodoro

Homocysteine and folate metabolism in depression

Bottiglieri, T. (2005) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Folate and B Vitamins ResearchTryptophan and brain disorders

Cited by 459

Plasma β-amyloid and white matter lesions in AD, MCI, and cerebral amyloid angiopathy

Gurol, M. E., Irizarry, M. C., Smith, E. E., Raju, S., Diaz-Arrastia, R., Bottiglieri, T., Rosand, J., Growdon, J. H., & Greenberg, S. M. (2006) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 339

Folate, vitamin B12, and homocysteine in major depressive disorder

D, M. F. M., Borus, J. S., Alpert, J. E., Nierenberg, A. A., Rosenbaum, J. F., & Bottiglieri, T. (1997) · American Journal of Psychiatry

Folate and B Vitamins ResearchTreatment of Major Depression

Cited by 287

S-Adenosyl-l-methionine (SAMe): from the bench to the bedside—molecular basis of a pleiotrophic molecule,,

Bottiglieri, T. (2002) · The American Journal of Clinical Nutrition

Folate and B Vitamins ResearchSulfur Compounds in Biology

Cited by 286

l -Methylfolate as Adjunctive Therapy for SSRI-Resistant Major Depression: Results of Two Randomized, Double-Blind, Parallel-Sequential Trials

Papakostas, G. I., Shelton, R. C., Zajecka, J. M., Etemad, B., Rickels, K., Clain, A., Baer, L., Dalton, E. D., Sacco, G. R., Schoenfeld, D., et al. (2012) · American Journal of Psychiatry

Treatment of Major DepressionFolate and B Vitamins Research

Cited by 275

Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation

Sontag, E., Nunbhakdi-Craig, V., Sontag, J.-M., Diaz-Arrastia, R., Ogris, E., Dayal, S., Lentz, S. R., Arning, E., & Bottiglieri, T. (2007) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsFolate and B Vitamins Research

Cited by 225

Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase

Hogema, B. M., Gupta, M., Senephansiri, H., Burlingame, T. G., Taylor, M., Jakobs, C., Schutgens, R. B. H., Froestl, W., Snead, O. C., Diaz-Arrastia, R., et al. (2001) · Nature Genetics

Metabolism and Genetic DisordersEpilepsy research and treatment

Cited by 157

Serum Folate, Vitamin B12, and Homocysteine in Major Depressive Disorder, Part 1: Predictors of Clinical Response in Fluoxetine-Resistant Depression

Papakostas, G. I., Petersen, T., Mischoulon, D., Ryan, J. L., Nierenberg, A. A., Bottiglieri, T., Rosenbaum, J. F., Alpert, J. E., & Fava, M. (2004) · The Journal of Clinical Psychiatry

Folate and B Vitamins ResearchTreatment of Major Depression

Cited by 113

Decreased C-Reactive Protein Levels in Alzheimer Disease

O'Bryant, S. E., Waring, S. C., Hobson, V., Hall, J. R., Moore, C. B., Bottiglieri, T., Massman, P., & Diaz-Arrastia, R. (2010) · Journal of Geriatric Psychiatry and Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 103

S-adenosylmethionine mediates inhibition of inflammatory response and changes in DNA methylation in human macrophages

Pfalzer, A. C., Choi, S.-W., Tammen, S. A., Park, L. K., Bottiglieri, T., Parnell, L. D., & Lamon-Fava, S. (2014) · Physiological Genomics

Epigenetics and DNA MethylationFolate and B Vitamins Research

Cited by 90

PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments

Nicholls, R. E., Sontag, J.-M., Zhang, H., Staniszewski, A., Yan, S., Kim, C. Y., Yim, M., Woodruff, C. M., Arning, E., Wasek, B., et al. (2016) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 56

Focal neurometabolic alterations in mice deficient for succinate semialdehyde dehydrogenase

Gibson, K. M., Schor, D. S. M., Gupta, M., Guerand, W. S., Senephansiri, H., Burlingame, T. G., Bartels, H., Hogema, B. M., Bottiglieri, T., Froestl, W., et al. (2002) · Journal of Neurochemistry

Metabolism and Genetic DisordersAmino Acid Enzymes and Metabolism

Cited by 55

Murine succinate semialdehyde dehydrogenase deficiency

Gupta, M., Hogema, B. M., Grompe, M., Bottiglieri, T. G., Concas, A., Biggio, G., Sogliano, C., Rigamonti, A. E., Pearl, P. L., Snead, O. C., et al. (2003) · Annals of Neurology

Metabolism and Genetic DisordersEpilepsy research and treatment

Cited by 50

Targeted metabolomic analysis in Parkinson’s disease brain frontal cortex and putamen with relation to cognitive impairment

Kalecký, K., & Bottiglieri, T. (2023) · npj Parkinson's Disease

Parkinson's Disease Mechanisms and TreatmentsMetabolomics and Mass Spectrometry Studies

Cited by 32

Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes

Kirby, T., Walters, D. C., Brown, M., Jansen, E., Salomons, G. S., Turgeon, C., Rinaldo, P., Arning, E., Ashcraft, P., Bottiglieri, T., et al. (2020) · Metabolic Brain Disease

Metabolism and Genetic DisordersMetabolomics and Mass Spectrometry Studies

Cited by 24

The 677C>T variant in methylenetetrahydrofolate reductase causes morphological and functional cerebrovascular deficits in mice

Reagan, A. M., Christensen, K. E., Graham, L. C., Bedwell, A. A., Eldridge, K., Speedy, R., Figueiredo, L. L., Persohn, S. C., Bottiglieri, T., Sasner, M., et al. (2021) · Journal of Cerebral Blood Flow & Metabolism

Folate and B Vitamins ResearchNeurological Disease Mechanisms and Treatments

Cited by 21