Mullighan, Charles G.

International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data

Arber, D. A., Orazi, A., Hasserjian, R. P., Borowitz, M. J., Calvo, K. R., Kvasnicka, H.-M., Wang, S. A., Bagg, A., Barbui, T., Branford, S., et al. (2022) · Blood

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 2,945

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Zhang, J., Ding, L., Holmfeldt, L., Wu, G., Heatley, S. L., Payne-Turner, D., Easton, J., Chen, X., Wang, J., Rusch, M., et al. (2012) · Nature

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

Cited by 1,596

Deletion of IKZF1 and Prognosis in Acute Lymphoblastic Leukemia

Mullighan, C. G., Su, X., Zhang, J., Radtke, I., Phillips, L. A. A., Miller, C. B., Ma, J., Liu, W., Cheng, C., Schulman, B. A., et al. (2009) · New England Journal of Medicine

Acute Lymphoblastic Leukemia researchLymphoma Diagnosis and Treatment

Cited by 1,422

Acute lymphoblastic leukaemia

Inaba, H., Greaves, M., & Mullighan, C. G. (2013) · The Lancet

Acute Lymphoblastic Leukemia researchLymphoma Diagnosis and Treatment

Cited by 1,074

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

Mullighan, C. G., Miller, C. B., Radtke, I., Phillips, L. A., Dalton, J., Ma, J., White, D., Hughes, T. P., Le Beau, M. M., Pui, C.-H., et al. (2008) · Nature

Acute Lymphoblastic Leukemia researchChronic Myeloid Leukemia Treatments

Cited by 1,072

The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia

Liu, Y., Easton, J., Shao, Y., Maciaszek, J., Wang, Z., Wilkinson, M. R., McCastlain, K., Edmonson, M., Pounds, S. B., Shi, L., et al. (2017) · Nature Genetics

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

Cited by 918

Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome

Kratz, C. P., Achatz, M. I., Brugières, L., Frebourg, T., Garber, J. E., Greer, M.-L. C., Hansford, J. R., Janeway, K. A., Kohlmann, W. K., McGee, R., et al. (2017) · Clinical Cancer Research

Cancer-related Molecular PathwaysMultiple and Secondary Primary Cancers

Cited by 534

Molecular genetics of B-precursor acute lymphoblastic leukemia

Mullighan, C. G. (2012) · Journal of Clinical Investigation

Acute Lymphoblastic Leukemia researchLymphoma Diagnosis and Treatment

Cited by 247

The genomic basis of childhood T-lineage acute lymphoblastic leukemia

Mullighan, C., Pölönen, P., Giacomo, D. D., Seffernick, A., Elsayed, A., Kimura, S., Benini, F., Montefiori, L., Wood, B., Xu, J., et al. (2023) · Nature

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

Cited by 173

The genomic basis of childhood T-lineage acute lymphoblastic leukaemia

Pölönen, P., Di Giacomo, D., Seffernick, A. E., Elsayed, A., Kimura, S., Benini, F., Montefiori, L. E., Wood, B. L., Xu, J., Chen, C., et al. (2024) · Nature

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

Cited by 173

NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells

Paugh, S. W., Bonten, E. J., Savic, D., Ramsey, L. B., Thierfelder, W. E., Gurung, P., Malireddi, R. K. S., Actis, M., Mayasundari, A., Min, J., et al. (2015) · Nature Genetics

Acute Lymphoblastic Leukemia researchInflammasome and immune disorders

Cited by 164

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Iacobucci, I., Wen, J., Meggendorfer, M., Choi, J. K., Shi, L., Pounds, S. B., Carmichael, C. L., Masih, K. E., Morris, S. M., Lindsley, R. C., et al. (2019) · Nature Genetics

Acute Myeloid Leukemia ResearchAcute Lymphoblastic Leukemia research

Cited by 155

Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells

Diouf, B., Cheng, Q., Krynetskaia, N. F., Yang, W., Cheok, M., Pei, D., Fan, Y., Cheng, C., Krynetskiy, E. Y., Geng, H., et al. (2011) · Nature Medicine

DNA Repair MechanismsAcute Lymphoblastic Leukemia research

Cited by 129

Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs

Dobson, S. M., García-Prat, L., Vanner, R. J., Wintersinger, J., Waanders, E., Gu, Z., McLeod, J., Gan, O. I., Grandal, I., Payne-Turner, D., et al. (2020) · Cancer Discovery

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

Cited by 94

PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia

Pang, S. H. M., Minnich, M., Gangatirkar, P., Zheng, Z., Ebert, A., Song, G., Dickins, R. A., Corcoran, L. M., Mullighan, C. G., Busslinger, M., et al. (2016) · Leukemia

Acute Lymphoblastic Leukemia researchGenomics and Chromatin Dynamics

Cited by 69

Notch/HES1-mediated PARP1 activation: a cell type–specific mechanism for tumor suppression

Kannan, S., Fang, W., Song, G., Mullighan, C. G., Hammitt, R., McMurray, J., & Zweidler-McKay, P. A. (2011) · Blood

Cell death mechanisms and regulationDevelopmental Biology and Gene Regulation

Cited by 66

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

Nishiguchi, G., Mascibroda, L. G., Young, S. M., Caine, E. A., Abdelhamed, S., Kooijman, J. J., Miller, D. J., Das, S., McGowan, K., Mayasundari, A., et al. (2024) · Nature Communications

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 57

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

Zhao, Y., Short, N. J., Kantarjian, H. M., Chang, T.-C., Ghate, P. S., Qu, C., Macaron, W., Jain, N., Thakral, B., Phillips, A. H., et al. (2023) · Blood

Acute Lymphoblastic Leukemia researchCAR-T cell therapy research

Cited by 41

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

Zhao, Y., Short, N. J., Kantarjian, H. M., Chang, T.-C., Ghate, P. S., Qu, C., Macaron, W., Jain, N., Thakral, B., Phillips, A. H., et al. (2024) · Blood

Acute Lymphoblastic Leukemia researchCAR-T cell therapy research

Cited by 41