Ryan, Kevin M.

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 6,680

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Klionsky, D. J., Abeliovich, H., Agostinis, P., Agrawal, D. K., Aliev, G., Askew, D. S., Baba, M., Baehrecke, E. H., Bahr, B. A., Ballabio, A., et al. (2008) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 2,230

Molecular definitions of autophagy and related processes

Galluzzi, L., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo‐San Pedro, J. M., Cecconi, F., Choi, A. M., Chu, C. T., Codogno, P., Colombo, M. I., et al. (2017) · The EMBO Journal

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,646

Autophagy in major human diseases

Klionsky, D. J., Petroni, G., Amaravadi, R. K., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo‐San Pedro, J. M., Cadwell, K., Cecconi, F., Choi, A. M. K., et al. (2021) · The EMBO Journal

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,585

DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis

Crighton, D., Wilkinson, S., O'Prey, J., Syed, N., Smith, P., Harrison, P. R., Gasco, M., Garrone, O., Crook, T., & Ryan, K. M. (2006) · Cell

Autophagy in Disease and TherapyCancer-related Molecular Pathways

Cited by 1,380

Autophagy in malignant transformation and cancer progression

Galluzzi, L., Pietrocola, F., Bravo‐San Pedro, J. M., Amaravadi, R. K., Baehrecke, E. H., Cecconi, F., Codogno, P., Debnath, J., Gewirtz, D. A., Karantza, V., et al. (2015) · The EMBO Journal

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,182

p53 and metabolism

Vousden, K. H., & Ryan, K. M. (2009) · Nature Reviews Cancer

Cancer-related Molecular PathwaysCancer, Hypoxia, and Metabolism

Cited by 959

Regulation and function of the p53 tumor suppressor protein

Ryan, K. M., Phillips, A. C., & Vousden, K. H. (2001) · Current Opinion in Cell Biology

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 721

p53 status determines the role of autophagy in pancreatic tumour development

Rosenfeldt, M. T., O’Prey, J., Morton, J. P., Nixon, C., MacKay, G., Mrowinska, A., Au, A., Rai, T. S., Zheng, L., Ridgway, R., et al. (2013) · Nature

Autophagy in Disease and TherapyPancreatic and Hepatic Oncology Research

Cited by 713

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis

Riley, J. S., Quarato, G., Cloix, C., Lopez, J., O'Prey, J., Pearson, M., Chapman, J., Sesaki, H., Carlin, L. M., Passos, J. F., et al. (2018) · The EMBO Journal

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 551

Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency

Giampazolias, E., Zunino, B., Dhayade, S., Bock, F., Cloix, C., Cao, K., Roca, A., Lopez, J., Ichim, G., Proïcs, E., et al. (2017) · Nature Cell Biology

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 258

Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

Sakamaki, J.-I., Wilkinson, S., Hahn, M., Tasdemir, N., O’Prey, J., Clark, W., Hedley, A., Nixon, C., Long, J. S., New, M., et al. (2017) · Molecular Cell

Autophagy in Disease and TherapyProtein Degradation and Inhibitors

Cited by 249

Evidence for the interplay between JNK and p53-DRAM signaling pathways in the regulation of autophagy

Lorin, S., Pierron, G., Ryan, K. M., Codogno, P., & Djavaheri-Mergny, M. (2010) · Autophagy

Autophagy in Disease and TherapyCell death mechanisms and regulation

Cited by 158

Senescence Sensitivity of Breast Cancer Cells Is Defined by Positive Feedback Loop between CIP2A and E2F1

Laine, A., Sihto, H., Come, C., Rosenfeldt, M. T., Zwolinska, A., Niemelä, M., Khanna, A., Chan, E. K., Kähäri, V.-M., Kellokumpu-Lehtinen, P.-L., et al. (2013) · Cancer Discovery

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 130

Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells

Beauvarlet, J., Bensadoun, P., Darbo, E., Labrunie, G., Rousseau, B., Richard, E., Draskovic, I., Londono-Vallejo, A., Dupuy, J.-W., Nath Das, R., et al. (2019) · Nucleic Acids Research

DNA and Nucleic Acid ChemistryTelomeres, Telomerase, and Senescence

Cited by 73

p53 directly regulates the glycosidase FUCA1 to promote chemotherapy-induced cell death

Baudot, A. D., Crighton, D., O'Prey, J., Somers, J., Sierra Gonzalez, P., & Ryan, K. M. (2016) · Cell Cycle

Cancer-related Molecular PathwaysGlycosylation and Glycoproteins Research

Cited by 31