Puschhof, Jens

SARS-CoV-2 productively infects human gut enterocytes

Lamers, M. M., Beumer, J., van der Vaart, J., Knoops, K., Puschhof, J., Breugem, T. I., Ravelli, R. B. G., Paul van Schayck, J., Mykytyn, A. Z., Duimel, H. Q., et al. (2020) · Science

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 1,573

Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli

Pleguezuelos-Manzano, C., Puschhof, J., Rosendahl Huber, A., van Hoeck, A., Wood, H. M., Nomburg, J., Gurjao, C., Manders, F., Dalmasso, G., Stege, P. B., et al. (2020) · Nature

Genetic factors in colorectal cancerCancer Genomics and Diagnostics

Cited by 1,208

Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition

Wong, G. S., Zhou, J., Liu, J. B., Wu, Z., Xu, X., Li, T., Xu, D., Schumacher, S. E., Puschhof, J., McFarland, J., et al. (2018) · Nature Medicine

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 266

Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo

Miao, Y., Ha, A., de Lau, W., Yuki, K., Santos, A. J. M., You, C., Geurts, M. H., Puschhof, J., Pleguezuelos-Manzano, C., Peng, W. C., et al. (2020) · Cell Stem Cell

Wnt/β-catenin signaling in development and cancerHedgehog Signaling Pathway Studies

Cited by 151

Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer

Rosendahl Huber, A., Pleguezuelos-Manzano, C., Puschhof, J., Ubels, J., Boot, C., Saftien, A., Verheul, M., Trabut, L. T., Groenen, N., van Roosmalen, M., et al. (2024) · Cancer Cell

Genetic factors in colorectal cancerCancer Genomics and Diagnostics

Cited by 106

Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures

Boonekamp, K. E., Kretzschmar, K., Wiener, D. J., Asra, P., Derakhshan, S., Puschhof, J., López-Iglesias, C., Peters, P. J., Basak, O., & Clevers, H. (2019) · Proceedings of the National Academy of Sciences

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 96

Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease

Valdés-Mas, R., Leshem, A., Zheng, D., Cohen, Y., Kern, L., Zmora, N., He, Y., Katina, C., Eliyahu-Miller, S., Yosef-Hevroni, T., et al. (2025) · Cell

Gut microbiota and healthInflammatory Bowel Disease

Cited by 89

Diet-microbiome interactions in cancer

Abdeen, S. K., Mastandrea, I., Stinchcombe, N., Puschhof, J., & Elinav, E. (2025) · Cancer Cell

Gut microbiota and healthNutritional Studies and Diet

Cited by 36

Visualization of Stem Cell Niche by Fluorescence Lifetime Imaging Microscopy

Okkelman, I. A., Puschhof, J., Papkovsky, D. B., & Dmitriev, R. I. (2020) · Methods in Molecular Biology

Advanced Fluorescence Microscopy TechniquesOptical Imaging and Spectroscopy Techniques

Cited by 15