Betsholtz, Christer

Analysis of the brain mural cell transcriptome

He, L., Vanlandewijck, M., Raschperger, E., Andaloussi Mäe, M., Jung, B., Lebouvier, T., Ando, K., Hofmann, J., Keller, A., & Betsholtz, C. (2016) · Scientific Reports

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 233

Increased Insulin Secretion and Glucose Tolerance in Mice Lacking Islet Amyloid Polypeptide (Amylin)

Gebre-Medhin, S., Mulder, H., Pekny, M., Westermark, G., Törnell, J., Westermark, P., Sundler, F., Ahrén, B., & Betsholtz, C. (1998) · Biochemical and Biophysical Research Communications

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 157

VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

Li, X., Padhan, N., Sjöström, E. O., Roche, F. P., Testini, C., Honkura, N., Sáinz-Jaspeado, M., Gordon, E., Bentley, K., Philippides, A., et al. (2016) · Nature Communications

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 149

Molecular anatomy of adult mouse leptomeninges

Pietilä, R., Del Gaudio, F., He, L., Vázquez-Liébanas, E., Vanlandewijck, M., Muhl, L., Mocci, G., Bjørnholm, K. D., Lindblad, C., Fletcher-Sandersjöö, A., et al. (2023) · Neuron

Barrier Structure and Function StudiesSingle-cell and spatial transcriptomics

Cited by 145

Notch3 Is Necessary for Blood Vessel Integrity in the Central Nervous System

Henshall, T. L., Keller, A., He, L., Johansson, B. R., Wallgard, E., Raschperger, E., Mäe, M. A., Jin, S., Betsholtz, C., & Lendahl, U. (2015) · Arteriosclerosis, Thrombosis, and Vascular Biology

Barrier Structure and Function StudiesCerebrovascular and genetic disorders

Cited by 145

Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2 – implications for microvascular inflammation and hypercoagulopathy in COVID-19

He, L., Mäe, M. A., Muhl, L., Sun, Y., Pietilä, R., Nahar, K., Liébanas, E. V., Fagerlund, M. J., Oldner, A., Liu, J., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 116

The Absence of Pericytes Does Not Increase the Sensitivity of Tumor Vasculature to Vascular Endothelial Growth Factor-A Blockade

Nisancioglu, M. H., Betsholtz, C., & Genové, G. (2010) · Cancer Research

Angiogenesis and VEGF in CancerBarrier Structure and Function Studies

Cited by 87

Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF β-receptor null mice

Kaminski, W. E., Lindahl, P., Lin, N. L., Broudy, V. C., Crosby, J. R., Hellström, M., Swolin, B., Bowen-Pope, D. F., Martin, P. J., Ross, R., et al. (2001) · Blood

Hematopoietic Stem Cell TransplantationPlatelet Disorders and Treatments

Cited by 77

Double function at the blood–brain barrier

Betsholtz, C. (2014) · Nature

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 63

Scrapie in Mice Deficient in Apolipoprotein E or Glial Fibrillary Acidic Protein

Tatzelt, J., Maeda, N., Pekny, M., Yang, S.-L., Betsholtz, C., Eliasson, C., Cayetano, J., Camerino, A. P., DeArmond, S. J., & Prusiner, S. B. (1996) · Neurology

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 59

Coexpression of the platelet-derived growth factor (PDGF) B chain and the PDGF beta receptor in isolated pancreatic islet cells stimulates DNA synthesis.

Welsh, M., Claesson-Welsh, L., Hallberg, A., Welsh, N., Betsholtz, C., Arkhammar, P., Nilsson, T., Heldin, C. H., & Berggren, P. O. (1990) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesProtein Kinase Regulation and GTPase Signaling

Cited by 40