Pritchard, Jonathan K.

High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation

Veyrieras, J.-B., Kudaravalli, S., Kim, S. Y., Dermitzakis, E. T., Gilad, Y., Stephens, M., & Pritchard, J. K. (2008) · PLoS Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 536

Trans effects on gene expression can drive omnigenic inheritance

Liu, X., Li, Y. I., & Pritchard, J. K. (2019) · Cell

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 523

Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data

Pique-Regi, R., Degner, J. F., Pai, A. A., Gaffney, D. J., Gilad, Y., & Pritchard, J. K. (2011) · Genome Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 521

Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data.

Degner, J. F., Marioni, J. C., Pai, A. A., Pickrell, J. K., Nkadori, E., Gilad, Y., & Pritchard, J. K. (2009) · Bioinformatics

Genomics and Phylogenetic StudiesRNA Research and Splicing

Cited by 502

Impact of regulatory variation from RNA to protein

Battle, A., Khan, Z., Wang, S. H., Mitrano, A., Ford, M. J., Pritchard, J. K., & Gilad, Y. (2015) · Science

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 471

Variable prediction accuracy of polygenic scores within an ancestry group

Mostafavi, H., Harpak, A., Agarwal, I., Conley, D., Pritchard, J. K., & Przeworski, M. (2020) · eLife

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 457

Adaptation–not by sweeps alone

Pritchard, J. K., & Di Rienzo, A. (2010) · Nature Reviews Genetics

Evolution and Genetic DynamicsGenetic diversity and population structure

Cited by 445

Identification of Genetic Variants That Affect Histone Modifications in Human Cells

McVicker, G., van de Geijn, B., Degner, J. F., Cain, C. E., Banovich, N. E., Raj, A., Lewellen, N., Myrthil, M., Gilad, Y., & Pritchard, J. K. (2013) · Science

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 436

The role of geography in human adaptation

Coop, G., Pickrell, J. K., Novembre, J., Kudaravalli, S., Li, J., Absher, D., Myers, R. M., Cavalli-Sforza, L. L., Feldman, M. W., & Pritchard, J. K. (2009) · PLoS Genetics

Forensic and Genetic ResearchGenetic diversity and population structure

Cited by 412

Abundant contribution of short tandem repeats to gene expression variation in humans

Gymrek, M., Willems, T., Guilmatre, A., Zeng, H., Markus, B., Georgiev, S., Daly, M. J., Price, A. L., Pritchard, J. K., Sharp, A. J., et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 410

Correction: A Map of Recent Positive Selection in the Human Genome

Voight, B. F., Kudaravalli, S., Wen, X., & Pritchard, J. K. (2006) · PLoS Biology

Evolution and Genetic DynamicsForensic and Genetic Research

Cited by 386

Detection of human adaptation during the past 2000 years

Field, Y., Boyle, E. A., Telis, N., Gao, Z., Gaulton, K. J., Golan, D., Yengo, L., Rocheleau, G., Froguel, P., McCarthy, M. I., et al. (2016) · Science

Forensic and Genetic ResearchEvolution and Genetic Dynamics

Cited by 383

Batch effects and the effective design of single-cell gene expression studies

Tung, P.-Y., Blischak, J. D., Hsiao, C. J., Knowles, D. A., Burnett, J. E., Pritchard, J. K., & Gilad, Y. (2017) · Scientific Reports

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 356

Reduced signal for polygenic adaptation of height in UK Biobank

Berg, J. J., Harpak, A., Sinnott-Armstrong, N., Joergensen, A. M., Mostafavi, H., Field, Y., Boyle, E. A., Zhang, X., Racimo, F., Pritchard, J. K., et al. (2019) · eLife

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 339

Systematic differences in discovery of genetic effects on gene expression and complex traits

Mostafavi, H., Spence, J. P., Naqvi, S., & Pritchard, J. K. (2023) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 336

Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions

Grubert, F., Zaugg, J. B., Kasowski, M., Ursu, O., Spacek, D. V., Martin, A. R., Greenside, P., Srivas, R., Phanstiel, D. H., Pekowska, A., et al. (2015) · Cell

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 319

Effect of predicted protein-truncating genetic variants on the human transcriptome

Rivas, M. A., Pirinen, M., Conrad, D. F., Lek, M., Tsang, E. K., Karczewski, K. J., Maller, J. B., Kukurba, K. R., DeLuca, D. S., Fromer, M., et al. (2015) · Science

Genomics and Rare DiseasesRNA Research and Splicing

Cited by 313

Noisy Splicing Drives mRNA Isoform Diversity in Human Cells

Pickrell, J. K., Pai, A. A., Gilad, Y., & Pritchard, J. K. (2010) · PLoS Genetics

RNA Research and SplicingGenomics and Phylogenetic Studies

Cited by 311

The deleterious mutation load is insensitive to recent population history.

Simons, Y. B., Turchin, M. C., Pritchard, J. K., & Sella, G. (2014) · Nature Genetics

Evolution and Genetic DynamicsGenomics and Rare Diseases

Cited by 279

The Genotype-Tissue Expression (GTEx) project

Lonsdale, J., Thomas, J., Salvatore, M., Phillips, R., Lo, E., Shad, S., Hasz, R., Walters, G., Garcia, F., Young, N., et al. (2013) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 263

Chromatin accessibility dynamics in a model of human forebrain development

Trevino, A. E., Sinnott-Armstrong, N., Andersen, J., Yoon, S.-J., Huber, N., Pritchard, J. K., Chang, H. Y., Greenleaf, W. J., & Pașca, S. P. (2020) · Science

Genomics and Chromatin DynamicsNeurogenesis and neuroplasticity mechanisms

Cited by 251

Primate Transcript and Protein Expression Levels Evolve Under Compensatory Selection Pressures

Khan, Z., Ford, M. J., Cusanovich, D. A., Mitrano, A., Pritchard, J. K., & Gilad, Y. (2013) · Science

Evolution and Genetic DynamicsGenomics and Phylogenetic Studies

Cited by 240

Functional Genetic Variants Revealed by Massively Parallel Precise Genome Editing

Sharon, E., Chen, S.-A. A., Khosla, N. M., Smith, J. D., Pritchard, J. K., & Fraser, H. B. (2018) · Cell

CRISPR and Genetic EngineeringEvolution and Genetic Dynamics

Cited by 225

Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment

Yamamoto, R., Wilkinson, A. C., Ooehara, J., Lan, X., Lai, C.-Y., Nakauchi, Y., Pritchard, J. K., & Nakauchi, H. (2018) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 202