Adaptation–not by sweeps alone
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There has been recent progress in identifying selective sweeps underlying a range of adaptations. Jonathan Pritchard and Anna Di Rienzo argue that many adaptive events in natural populations may occur by polygenic adaptation, which would largely go undetected by conventional methods for detecting selection.
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Selective sweep scans are limited in their ability to detect polygenic adaptation of complex traits that may be due to small shifts in allele frequency at many loci.
“Selective sweep scans are limited in their ability to detect polygenic adaptation of complex traits that may be due to small shifts in allele frequency at many loci (Pritchard and Di Rienzo 2010).”
From The neural crest cell hypothesis: no unified explanation for domestication (2021) · cites this paper as Pritchard and Di Rienzo 2010
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Cites
Introduction to Quantitative Genetics.
Edwards, A. W. F., & Falconer, D. S. (1982) · Biometrics · doi:10.2307/2529912 · Cited by 21,447 · see citing works
Introduction to Quantitative Genetics
J.-M., G., & Falconer, D. S. (1962) · Population · doi:10.2307/1525780 · Cited by 3,773 · see citing works
The hitch-hiking effect of a favourable gene
Smith, J. M., & Haigh, J. (1974) · Genetical Research · doi:10.1017/s0016672300014634 · Cited by 3,415 · see citing works
The hitch-hiking effect of a favourable gene
MAYNARD, J., & Haigh, J. (2007) · Genetics Research · doi:10.1017/s0016672308009579 · Cited by 2,663 · see citing works
The causes of molecular evolution
Gillespie, J. H. (1992) · Choice Reviews Online · doi:10.5860/choice.30-2064 · Cited by 1,244 · see citing works
Positive Natural Selection in the Human Lineage
Sabeti, P. C., Schaffner, S. F., Fry, B., Lohmueller, J., Varilly, P., Shamovsky, O., Palma, A., Mikkelsen, T. S., Altshuler, D., & Lander, E. S. (2006) · Science · doi:10.1126/science.1124309 · Cited by 1,157 · see citing works
Hermisson (2005) · doi:10.1534/genetics.104.036947 · Cited by 1,009 · see citing works
The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation
Pritchard, J. K., Pickrell, J. K., & Coop, G. (2010) · Current Biology · doi:10.1016/j.cub.2009.11.055 · Cited by 932 · see citing works
Self-citationUnderstanding quantitative genetic variation
Barton, N., & Keightley, P. D. (2002) · Nature Reviews Genetics · doi:10.1038/nrg700 · Cited by 839 · see citing works
Genome-wide association analysis identifies 20 loci that influence adult height
Initiative, D. G., Weedon, M. N., The Wellcome Trust Case Control Consortium, Cambridge GEM Consortium, Lango, H., Lindgren, C. M., Wallace, C., Evans, D. M., Mangino, M., Freathy, R. M., et al. (2008) · Nature Genetics · doi:10.1038/ng.121 · Cited by 826 · see citing works
The Causes of Molecular Evolution
Gillespie, J. H. (1992) · doi:10.1093/oso/9780195068832.001.0001 · Cited by 644 · see citing works
Population genetics: a concise guide
(1998) · Choice Reviews Online · doi:10.5860/choice.35-4473 · Cited by 632 · see citing works
Recent and ongoing selection in the human genome
Nielsen, R., Hellmann, I., Hubisz, M. J., Bustamante, C. D., & Clark, A. G. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2187 · Cited by 501 · see citing works
Barton, N. (2000) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2000.0716 · Cited by 475 · see citing works
Widespread Genomic Signatures of Natural Selection in Hominid Evolution
McVicker, G., Gordon, D., Davis, C., & Green, P. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000471 · Cited by 456 · see citing works
Gillespie, J. (2004) · doi:10.56021/9780801880087 · Cited by 366 · see citing works
Human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency
Hancock, A. M., Witonsky, D., Ehler, E., Alkorta‐Aranburu, G., Beall, C. M., Gebremedhin, A., Sukernik, R. I., Utermann, G., Pritchard, J. K., Coop, G., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914625107 · Cited by 255 · see citing works
Self-citationTwo steps forward, one step back: the pleiotropic effects of favoured alleles
Otto, S. P. (2004) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2003.2635 · Cited by 202 · see citing works
Selective Sweep at a Quantitative Trait Locus in the Presence of Background Genetic Variation
Chevin, L. (2008) · Genetics · doi:10.1534/genetics.108.093351 · Cited by 179 · see citing works
Evolution of the human pygmy phenotype
Perry, G. H., & Dominy, N. J. (2009) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2008.11.008 · Cited by 161 · see citing works
Adaptations to new environments in humans: the role of subtle allele frequency shifts
Hancock, A. M., Alkorta‐Aranburu, G., Witonsky, D., & Rienzo, A. D. (2010) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2010.0032 · Cited by 140 · see citing works
The Distribution of Beneficial and Fixed Mutation Fitness Effects Close to an Optimum
Martin, G., & Lenormand, T. (2008) · Genetics · doi:10.1534/genetics.108.087122 · Cited by 96 · see citing works
Directional Positive Selection on an Allele of Arbitrary Dominance
Teshima, K. M., & Przeworski, M. (2005) · Genetics · doi:10.1534/genetics.105.044065 · Cited by 85 · see citing works
Kopp, M., & Hermisson, J. (2009) · Genetics · doi:10.1534/genetics.109.106195 · Cited by 78 · see citing works
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Cited by
Sorted by citations
Ecological genomics of local adaptation
Savolainen, O., Lascoux, M., & Merilä, J. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3522 · Cited by 1,388 · see citing works
The evolutionary origins of pesticide resistance
Hawkins, N. J., Bass, C., Dixon, A. L., & Neve, P. (2018) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12440 · Cited by 847 · see citing works
A practical guide to environmental association analysis in landscape genomics
Rellstab, C., Gugerli, F., Eckert, A. J., Hancock, A. M., & Holderegger, R. (2015) · Molecular Ecology · doi:10.1111/mec.13322 · Cited by 828 · see citing works
Detecting Natural Selection in Genomic Data
Vitti, J. J., Grossman, S. R., & Sabeti, P. C. (2013) · Annual Review of Genetics · doi:10.1146/annurev-genet-111212-133526 · Cited by 694 · see citing works
Lotterhos, K. E., & Whitlock, M. C. (2015) · Molecular Ecology · doi:10.1111/mec.13100 · Cited by 568 · see citing works
Progress and promise of genome-wide association studies for human complex trait genetics
Stranger, B. E., Stahl, E. A., & Raj, T. (2011) · Genetics · doi:10.1534/genetics.110.120907 · Cited by 567 · see citing works
Lotterhos, K. E., & Whitlock, M. C. (2014) · Molecular Ecology · doi:10.1111/mec.12725 · Cited by 534 · see citing works
Genomic signatures of selection at linked sites: unifying the disparity among species
Cutter, A. D., & Payseur, B. A. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3425 · Cited by 465 · see citing works
Variable prediction accuracy of polygenic scores within an ancestry group
Mostafavi, H., Harpak, A., Agarwal, I., Conley, D., Pritchard, J. K., & Przeworski, M. (2020) · eLife · doi:10.7554/elife.48376 · Cited by 457 · see citing works
Self-citationEvolutionary genetics of plant adaptation
Anderson, J. T., Willis, J. H., & Mitchell‐Olds, T. (2011) · Trends in Genetics · doi:10.1016/j.tig.2011.04.001 · Cited by 438 · see citing works
QST–FST comparisons: evolutionary and ecological insights from genomic heterogeneity
Leinonen, T., McCairns, R. J. S., O'Hara, R. B., & Merilä, J. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3395 · Cited by 422 · see citing works
Polygenic adaptation: a unifying framework to understand positive selection
Barghi, N., Hermisson, J., & Schlötterer, C. (2020) · Nature Reviews Genetics · doi:10.1038/s41576-020-0250-z · Cited by 404 · see citing works
Vaysse, A., Ratnakumar, A., Derrien, T., Axelsson, E., Pielberg, G., Sigurðsson, S., Fall, T., Seppälä, E. H., Hansen, M. S., Lawley, C., et al. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002316 · Cited by 390 · see citing works
Signatures of negative selection in the genetic architecture of human complex traits
Zeng, J., de Vlaming, R., Wu, Y., Robinson, M. R., Lloyd-Jones, L. R., Yengo, L., Yap, C. X., Xue, A., Sidorenko, J., McRae, A. F., et al. (2018) · Nature Genetics · doi:10.1038/s41588-018-0101-4 · Cited by 391 · see citing works
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis
Diabetes Genetics Replication and Meta-analysis Consortium, Stahl, E. A., Myocardial Infarction Genetics Consortium, Wegmann, D., Trynka, G., Gutierrez-Achury, J., Do, R., Voight, B. F., Kraft, P., Chen, R., et al. (2012) · Nature Genetics · doi:10.1038/ng.2232 · Cited by 388 · see citing works
On Detecting Incomplete Soft or Hard Selective Sweeps Using Haplotype Structure
Ferrer-Admetlla, A., Liang, M., Korneliussen, T. S., & Nielsen, R. (2014) · Molecular Biology and Evolution · doi:10.1093/molbev/msu077 · Cited by 362 · see citing works
Glover, K. A., Solberg, M. F., McGinnity, P., Hindar, K., Verspoor, E., Coulson, M. W., Hansen, M. M., Araki, H., Skaala, Ø., & Svåsand, T. (2017) · Fish and Fisheries · doi:10.1111/faf.12214 · Cited by 359 · see citing works
The genetic differentiation at quantitative trait loci under local adaptation
Corre, V. L., & Kremer, A. (2012) · Molecular Ecology · doi:10.1111/j.1365-294x.2012.05479.x · Cited by 350 · see citing works
Evans, L. M., Slavov, G. T., Rodgers‐Melnick, E., Martin, J., Ranjan, P., Muchero, W., Brunner, A. M., Schackwitz, W., Gunter, L. E., Chen, J., et al. (2014) · Nature Genetics · doi:10.1038/ng.3075 · Cited by 345 · see citing works
Evidence of widespread selection on standing variation in Europe at height-associated SNPs
Turchin, M. C., Chiang, C. W., Palmer, C. D., Sankararaman, S., Reich, D., Genetic Investigation of ANthropometric Traits (GIANT) Consortium, & Hirschhorn, J. N. (2012) · Nature Genetics · doi:10.1038/ng.2368 · Cited by 329 · see citing works
Genome scan methods against more complex models: when and how much should we trust them?
de Villemereuil, P., Frichot, É., Bazin, É., François, O., & Gaggiotti, O. E. (2014) · Molecular Ecology · doi:10.1111/mec.12705 · Cited by 306 · see citing works
Genetic redundancy fuels polygenic adaptation in Drosophila
Barghi, N., Tobler, R., Nolte, V., Jakšić, A. M., Mallard, F., Otte, K. A., Dolezal, M., Taus, T., Kofler, R., & Schlötterer, C. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000128 · Cited by 293 · see citing works
Monitoring adaptive genetic responses to environmental change
Hansen, M. M., Olivieri, I., Waller, D. M., Nielsen, E. E., & The GeM Working Group (2012) · Molecular Ecology · doi:10.1111/j.1365-294x.2011.05463.x · Cited by 291 · see citing works
Gagnaire, P., Broquet, T., Aurelle, D., Viard, F., Souissi, A., Bonhomme, F., Arnaud‐Haond, S., & Bierne, N. (2015) · Evolutionary Applications · doi:10.1111/eva.12288 · Cited by 272 · see citing works
Thinking About the Evolution of Complex Traits in the Era of Genome-Wide Association Studies
Sella, G., & Barton, N. (2019) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-083115-022316 · Cited by 263 · see citing works
Cho, J. H., & Feldman, M. A. (2015) · Nature Medicine · doi:10.1038/nm.3897 · Cited by 259 · see citing works
Forensic genetic analysis of bio-geographical ancestry
Phillips, C. (2015) · Forensic Science International Genetics · doi:10.1016/j.fsigen.2015.05.012 · Cited by 257 · see citing works
Bernatchez, L. (2016) · Journal of Fish Biology · doi:10.1111/jfb.13145 · Cited by 244 · see citing works
Evaluation of redundancy analysis to identify signatures of local adaptation
Capblancq, T., Luu, K., Blum, M. G. B., & Bazin, É. (2018) · Molecular Ecology Resources · doi:10.1111/1755-0998.12906 · Cited by 239 · see citing works
Admixture facilitates genetic adaptations to high altitude in Tibet
Jeong, C., Alkorta‐Aranburu, G., Basnyat, B., Neupane, M., Witonsky, D., Pritchard, J. K., Beall, C. M., & Rienzo, A. D. (2014) · Nature Communications · doi:10.1038/ncomms4281 · Cited by 237 · see citing works
Self-citationRellstab, C., Zoller, S., Walthert, L., Lesur, I., Pluess, A. R., Graf, R., Bodénès, C., Sperisen, C., Kremer, A., & Gugerli, F. (2016) · Molecular Ecology · doi:10.1111/mec.13889 · Cited by 228 · see citing works
Gagnaire, P., Pavey, S. A., Normandeau, É., & Bernatchez, L. (2013) · Evolution · doi:10.1111/evo.12075 · Cited by 195 · see citing works
The Human Condition—A Molecular Approach
Pääbo, S. (2014) · Cell · doi:10.1016/j.cell.2013.12.036 · Cited by 197 · see citing works
Palla, L., & Dudbridge, F. (2015) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2015.06.005 · Cited by 185 · see citing works
Adaptations to Climate-Mediated Selective Pressures in Sheep
Lv, F., Agha, S., Kantanen, J., Colli, L., Stucki, S., Kijas, J., Joost, S., Li, M.-H., & Ajmone‐Marsan, P. (2014) · Molecular Biology and Evolution · doi:10.1093/molbev/msu264 · Cited by 193 · see citing works
Can Population Genetics Adapt to Rapid Evolution?
Messer, P. W., Ellner, S. P., & Hairston, N. G. (2016) · Trends in Genetics · doi:10.1016/j.tig.2016.04.005 · Cited by 193 · see citing works
Prospects and limitations of genomic offset in conservation management
Rellstab, C., Dauphin, B., & Expósito‐Alonso, M. (2021) · Evolutionary Applications · doi:10.1111/eva.13205 · Cited by 191 · see citing works
Modeling Evolution Using the Probability of Fixation: History and Implications
McCandlish, D. M., & Stoltzfus, A. (2014) · The Quarterly Review of Biology · doi:10.1086/677571 · Cited by 182 · see citing works
Gossmann, T. I., Keightley, P. D., & Eyre‐Walker, A. (2012) · Genome Biology and Evolution · doi:10.1093/gbe/evs027 · Cited by 180 · see citing works
Genomic Signature of Adaptation to Climate in Medicago truncatula
Yoder, J. B., Stanton‐Geddes, J., Zhou, P., Briskine, R. V., Young, N. D., & Tiffin, P. (2014) · Genetics · doi:10.1534/genetics.113.159319 · Cited by 173 · see citing works
A practical introduction to Random Forest for genetic association studies in ecology and evolution
Brieuc, M. S. O., Waters, C. D., Drinan, D. P., & Naish, K. A. (2018) · Molecular Ecology Resources · doi:10.1111/1755-0998.12773 · Cited by 172 · see citing works
Detecting Polygenic Evolution: Problems, Pitfalls, and Promises
Wellenreuther, M., & Hansson, B. (2016) · Trends in Genetics · doi:10.1016/j.tig.2015.12.004 · Cited by 168 · see citing works
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Flatt, T. (2020) · Genetics · doi:10.1534/genetics.119.300160 · Cited by 165 · see citing works
Haasl, R. J., & Payseur, B. A. (2015) · Molecular Ecology · doi:10.1111/mec.13339 · Cited by 157 · see citing works
Predicting Responses to Contemporary Environmental Change Using Evolutionary Response Architectures
Bay, R. A., Rose, N. H., Barrett, R. D. H., Bernatchez, L., Ghalambor, C. K., Lasky, J. R., Brem, R. B., Palumbi, S. R., & Ralph, P. J. (2017) · The American Naturalist · doi:10.1086/691233 · Cited by 156 · see citing works
Lohmueller, K. E., Albrechtsen, A., Li, Y., Kim, S. Y., Korneliussen, T. S., Vinckenbosch, N., Tian, G., Huerta‐Sánchez, E., Feder, A. F., Grarup, N., et al. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002326 · Cited by 149 · see citing works
Population genomics from pool sequencing
Luca Ferretti, A., Ramos-Onsins, S. E., & Miguel Pérez-enciso, A. (2013) · Molecular Ecology · doi:10.1111/mec.12522 · Cited by 147 · see citing works
The transition to modernity and chronic disease: mismatch and natural selection
Corbett, S. J., Courtiol, A., Lummaa, V., Moorad, J. A., & Stearns, S. C. (2018) · Nature Reviews Genetics · doi:10.1038/s41576-018-0012-3 · Cited by 153 · see citing works
Genome‐wide scans detect adaptation to aridity in a widespread forest tree species
Steane, D. A., Potts, B. M., McLean, E. H., Prober, S. M., Stock, W. D., Vaillancourt, R. E., & Byrne, M. M. (2014) · Molecular Ecology · doi:10.1111/mec.12751 · Cited by 147 · see citing works
Polygenic adaptation: From sweeps to subtle frequency shifts
Höllinger, I., Pennings, P. S., & Hermisson, J. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1008035 · Cited by 146 · see citing works
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Heritability and the evolution of cognitive traits: Table 1
Croston, R., Branch, C. L., Kozlovsky, D. Y., Dukas, R., & Витальевич, П. В. (2015) · Behavioral Ecology · doi:10.1093/beheco/arv088 · Cited by 143 · see citing works
Jarvis, J. P., Scheinfeldt, L. B., Soi, S., Lambert, C., Omberg, L., Ferwerda, B., Froment, A., Bodo, J.-M., Beggs, W., Hoffman, G., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002641 · Cited by 139 · see citing works
Lamichhaney, S., Fuentes‐Pardo, A. P., Rafati, N., Ryman, N., McCracken, G. R., Bourne, C. M., Singh, R., Ruzzante, D. E., & Andersson, L. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1617728114 · Cited by 138 · see citing works
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Mahony, C. R., MacLachlan, I. R., Lind, B. M., Yoder, J. B., Wang, T., & Aitken, S. N. (2019) · Evolutionary Applications · doi:10.1111/eva.12871 · Cited by 128 · see citing works
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Local Adaptation in the Flowering-Time Gene Network of Balsam Poplar, Populus balsamifera L.
Keller, S. R., Levsen, N. D., Olson, M. S., & Tiffin, P. (2012) · Molecular Biology and Evolution · doi:10.1093/molbev/mss121 · Cited by 122 · see citing works
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Gagnaire, P., & Gaggiotti, O. E. (2016) · Current Zoology · doi:10.1093/cz/zow088 · Cited by 118 · see citing works
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Polygenic adaptation after a sudden change in environment
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The genomics of local adaptation in trees: are we out of the woods yet?
Lind, B. M., Menon, M., Bolte, C. E., Faske, T. M., & Eckert, A. (2017) · bioRxiv · doi:10.1007/s11295-017-1224-y · Cited by 98 · see citing works
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Evolution of polygenic traits under global vs local adaptation
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Vocal learning as a preadaptation for the evolution of human beat perception and synchronization
Patel, A. D. (2021) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2020.0326 · Cited by 112 · see citing works
Sandoval‐Castillo, J., Gates, K., Brauer, C. J., Smith, S., Bernatchez, L., & Beheregaray, L. B. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1921124117 · Cited by 106 · see citing works
Fraïssé, C., Belkhir, K., Welch, J. J., & Bierne, N. (2015) · Molecular Ecology · doi:10.1111/mec.13299 · Cited by 109 · see citing works
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Disentangling structural genomic and behavioural barriers in a sea of connectivity
Barth, J. M. I., Villegas‐Ríos, D., Freitas, C., Moland, E., Star, B., André, C., Knutsen, H., Bradbury, I., Dierking, J., Petereit, C., et al. (2019) · Molecular Ecology · doi:10.1111/mec.15010 · Cited by 102 · see citing works
Evolution of Anopheles gambiae in Relation to Humans and Malaria
White, B. J., Collins, F. H., & Besansky, N. J. (2011) · Annual Review of Ecology Evolution and Systematics · doi:10.1146/annurev-ecolsys-102710-145028 · Cited by 105 · see citing works
Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers
Perry, G. H., Foll, M., Grenier, J.-C., Patin, E., Nédélec, Y., Pacis, A., Barakatt, M., Gravel, S., Zhou, X., Nsobya, S. L., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1402875111 · Cited by 105 · see citing works
Hecht, B. C., Matala, A. P., Hess, J. E., & Narum, S. R. (2015) · Molecular Ecology · doi:10.1111/mec.13409 · Cited by 102 · see citing works
Riverscape genomics of a threatened fish across a hydroclimatically heterogeneous river basin
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Museum samples reveal rapid evolution by wild honey bees exposed to a novel parasite
Mikheyev, A. S., Tin, M. M. Y., Arora, J., & Seeley, T. D. (2015) · Nature Communications · doi:10.1038/ncomms8991 · Cited by 100 · see citing works
Understanding rare and common diseases in the context of human evolution
Quintana‐Murci, L. (2016) · Genome biology · doi:10.1186/s13059-016-1093-y · Cited by 97 · see citing works
Quantifying the Variation in the Effective Population Size Within a Genome
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Bellon, M. R., Mastretta‐Yanes, A., Mendoza, A. P., Ortiz-Santamaría, D., Oliveros‐Galindo, O., Perales, H., Acevedo, F., & Sarukhán, J. (2018) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2018.1049 · Cited by 98 · see citing works
Wållberg, A., Schöning, C., Webster, M. T., & Hasselmann, M. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006792 · Cited by 96 · see citing works
Bourgeois, Y., & Warren, B. H. (2021) · Molecular Ecology · doi:10.1111/mec.15989 · Cited by 96 · see citing works
Travisano, M., & Shaw, R. G. (2012) · Evolution · doi:10.1111/j.1558-5646.2012.01802.x · Cited by 94 · see citing works
Global genetic differentiation of complex traits shaped by natural selection in humans
Guo, J., Wu, Y., Zhu, Z., Zheng, Z., Trzaskowski, M., Zeng, J., Robinson, M. R., Visscher, P. M., & Yang, J. (2018) · Nature Communications · doi:10.1038/s41467-018-04191-y · Cited by 87 · see citing works
Polimanti, R. A., & Gelernter, J. E. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006618 · Cited by 91 · see citing works
Rapid Adaptation of a Polygenic Trait After a Sudden Environmental Shift
Jain, K., & Stephan, W. (2017) · Genetics · doi:10.1534/genetics.116.196972 · Cited by 88 · see citing works
Mojica, J. P., Lee, Y. W., Willis, J. H., & Kelly, J. K. (2012) · Molecular Ecology · doi:10.1111/j.1365-294x.2012.05662.x · Cited by 90 · see citing works
Dayan, D. I., Du, X., Baris, T. Z., Wagner, D. N., Crawford, D. L., & Oleksiak, M. F. (2019) · BMC Evolutionary Biology · doi:10.1186/s12862-019-1392-5 · Cited by 90 · see citing works
San, J. E., Baichoo, S., Kanzi, A. M., Moosa, Y., Lessells, R. J., Fonseca, V., Mogaka, J., Power, R. A., & de Oliveira, T. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.03119 · Cited by 84 · see citing works
Rech, G. E., Bogaerts-Márquez, M., Barrón, M. G., Merenciano, M., Villanueva‐Cañas, J. L., Horváth, V., Fiston-Lavier, A.-S., Luyten, I., Venkataram, S., Quesneville, H., et al. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1007900 · Cited by 89 · see citing works
Zhang, Y., Wang, Y., Li, Y., Wu, J., Wang, X., Bian, C., Tian, Y., Sun, G., Han, R., Liu, X., et al. (2020) · Heredity · doi:10.1038/s41437-020-00365-x · Cited by 89 · see citing works
From the Past to the Future: Considering the Value and Limits of Evolutionary Prediction
Shaw, R. G. (2018) · The American Naturalist · doi:10.1086/700565 · Cited by 88 · see citing works
Jeong, C., Witonsky, D., Basnyat, B., Neupane, M., Beall, C. M., Childs, G. H., Craig, S. R., Novembre, J., & Rienzo, A. D. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007650 · Cited by 87 · see citing works
McGivney, B. A., Han, H., Corduff, L. R., Katz, L. M., Tozaki, T., MacHugh, D. E., & Hill, E. W. (2020) · Scientific Reports · doi:10.1038/s41598-019-57389-5 · Cited by 85 · see citing works
Koch, E. L., Morales, H. E., Larsson, J., Westram, A. M., Faria, R., Lemmon, A. R., Lemmon, E. M., Johannesson, K., & Butlin, R. K. (2021) · Evolution Letters · doi:10.1002/evl3.227 · Cited by 85 · see citing works
Limited Evidence for Classic Selective Sweeps in African Populations
Granka, J. M., Henn, B. M., Gignoux, C. R., Kidd, J. M., Bustamante, C. D., & Feldman, M. W. (2012) · Genetics · doi:10.1534/genetics.112.144071 · Cited by 78 · see citing works
Selection on a Genetic Polymorphism Counteracts Ecological Speciation in a Stick Insect
Comeault, A. A., Flaxman, S. M., Riesch, R., Curran, E. V., Soria‐Carrasco, V., Gompert, Z., Farkas, T. E., Muschick, M., Parchman, T. L., Schwander, T., et al. (2015) · Current Biology · doi:10.1016/j.cub.2015.05.058 · Cited by 81 · see citing works
The genomic basis of environmental adaptation in house mice
Phifer‐Rixey, M., Bi, K., Ferris, K. G., Sheehan, M. J., Lin, D., Mack, K. L., Keeble, S. M., Suzuki, T. A., Good, J. M., & Nachman, M. W. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007672 · Cited by 80 · see citing works
Adaptations to local environments in modern human populations
Jeong, C., & Di Rienzo, A. (2014) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2014.06.011 · Cited by 80 · see citing works
Differentiated demographic histories and local adaptations between Sherpas and Tibetans
Zhang, C., Lü, Y., Feng, Q., Wang, X., Lou, H., Liu, J., Ning, Z., Yuan, K., Wang, Y., Zhou, Y., et al. (2017) · Genome biology · doi:10.1186/s13059-017-1242-y · Cited by 80 · see citing works
Modes of Rapid Polygenic Adaptation
Jain, K., & Stephan, W. (2017) · Molecular Biology and Evolution · doi:10.1093/molbev/msx240 · Cited by 76 · see citing works
- Authors
- Pritchard, J. K., & Di Rienzo, A.
- Affiliations
- Howard Hughes Medical Institute (US)
- Venue
- Nature Reviews Genetics
- Published
- 2010-09-14
- Volume
- 11
- Issue
- 10
- Pages
- 665-667
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- PMC
- PMC4652788
- OpenAlex
- W1525285200
- Cited by
- 445
- References
- 24
- Citations by year
- 2026: 16 · 2025: 22 · 2024: 20 · 2023: 16 · 2022: 19 · 2021: 37 · 2020: 43 · 2019: 27 · 2018: 41 · 2017: 36 · 2016: 32 · 2015: 35 · 2014: 30 · 2013: 23 · 2012: 29
- FWCI
- 2.40
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Genetics (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Howard Hughes Medical Institute
- National Institutes of Health
- National Institute of Mental Health (R01MH084703, MH84703)
- National Institute of General Medical Sciences (GM79558, R01GM079558)
- National Institute of Diabetes and Digestive and Kidney Diseases (DK 56670, R01DK056670)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- polygenic adaptation, selective sweeps, natural selection, adaptation, quantitative traits
- MeSH terms
- Adaptation, Physiological, Animals, Genetics, Population, Humans, Selection, Genetic, Evolution, Molecular, Multifactorial Inheritance
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