Levine, Morgan E.

An epigenetic biomarker of aging for lifespan and healthspan

Levine, M. E., Lu, A. T., Quach, A., Chen, B. H., Assimes, T. L., Bandinelli, S., Hou, L., Baccarelli, A. A., Stewart, J. D., Li, Y., et al. (2018) · Aging

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 3,675

DNA methylation-based measures of biological age: meta-analysis predicting time to death

Chen, B. H., Marioni, R. E., Colicino, E., Peters, M. J., Ward-Caviness, C. K., Tsai, P.-C., Roetker, N. S., Just, A. C., Demerath, E. W., Guan, W., et al. (2016) · Aging

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 1,126

Quantification of biological aging in young adults

Belsky, D. W., Caspi, A., Houts, R., Cohen, H. J., Corcoran, D. L., Danese, A., Harrington, H., Israel, S., Levine, M. E., Schaefer, J. D., et al. (2015) · Proceedings of the National Academy of Sciences

Genetics, Aging, and Longevity in Model OrganismsAging and Gerontology Research

Cited by 1,012

Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population

Levine, M. E., Suarez, J. A., Brandhorst, S., Balasubramanian, P., Cheng, C.-W., Madia, F., Fontana, L., Mirisola, M. G., Guevara-Aguirre, J., Wan, J., et al. (2014) · Cell Metabolism

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 910

Reprogramming to recover youthful epigenetic information and restore vision

Lu, Y., Brommer, B., Tian, X., Krishnan, A., Meer, M., Wang, C., Vera, D. L., Zeng, Q., Yu, D., Bonkowski, M. S., et al. (2020) · Nature

Epigenetics and DNA MethylationPluripotent Stem Cells Research

Cited by 820

Epigenetic clock analysis of diet, exercise, education, and lifestyle factors

Quach, A., Levine, M. E., Tanaka, T., Lu, A. T., Chen, B. H., Ferrucci, L., Ritz, B., Bandinelli, S., Neuhouser, M. L., Beasley, J. M., et al. (2017) · Aging

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 801

A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study

Liu, Z., Kuo, P.-L., Horvath, S., Crimmins, E., Ferrucci, L., & Levine, M. (2018) · PLOS Medicine

Frailty in Older AdultsGenetics, Aging, and Longevity in Model Organisms

Cited by 754

Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning

Levine, M. E., Lu, A. T., Bennett, D. A., & Horvath, S. (2015) · Aging

Dementia and Cognitive Impairment ResearchEpigenetics and DNA Methylation

Cited by 455

Time and the Metrics of Aging

Ferrucci, L., Levine, M. E., Kuo, P.-L., & Simonsick, E. M. (2018) · Circulation Research

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 303

Loneliness, eudaimonia, and the human conserved transcriptional response to adversity

Cole, S. W., Levine, M. E., Arevalo, J. M. G., Ma, J., Weir, D. R., & Crimmins, E. M. (2015) · Psychoneuroendocrinology

Health disparities and outcomesStress Responses and Cortisol

Cited by 238

Underlying features of epigenetic aging clocks in vivo and in vitro.

Liu, Z., Leung, D., Thrush, K., Zhao, W., Ratliff, S., Tanaka, T., Schmitz, L. L., Smith, J. A., Ferrucci, L., & Levine, M. E. (2020) · Aging Cell

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 227

A complex systems approach to aging biology

Cohen, A. A., Ferrucci, L., Fülöp, T., Gravel, D., Hao, N., Kriete, A., Levine, M. E., Lipsitz, L. A., Olde Rikkert, M. G. M., Rutenberg, A., et al. (2022) · Nature Aging

Genetics, Aging, and Longevity in Model OrganismsPhilosophy of Biology and Scientific Explanation

Cited by 221

Associations of Age, Sex, Race/Ethnicity, and Education With 13 Epigenetic Clocks in a Nationally Representative U.S. Sample: The Health and Retirement Study

Crimmins, E. M., Thyagarajan, B., Levine, M. E., Weir, D. R., & Faul, J. (2021) · The Journals of Gerontology: Series A

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 213

Epigenetic-based age acceleration in a representative sample of older Americans: Associations with aging-related morbidity and mortality

Faul, J. D., Kim, J. K., Levine, M. E., Thyagarajan, B., Weir, D. R., & Crimmins, E. M. (2023) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 211

The Impact of Insulin Resistance and Inflammation on the Association Between Sarcopenic Obesity and Physical Functioning

Levine, M. E., & Crimmins, E. M. (2012) · Obesity

Nutrition and Health in AgingMuscle Physiology and Disorders

Cited by 186

Epigenetic Aging and Immune Senescence in Women With Insomnia Symptoms: Findings From the Women’s Health Initiative Study

Carroll, J. E., Irwin, M. R., Levine, M., Seeman, T. E., Absher, D., Assimes, T., & Horvath, S. (2017) · Biological Psychiatry

Sleep and related disordersEpigenetics and DNA Methylation

Cited by 173

Childhood and later life stressors and increased inflammatory gene expression at older ages

Levine, M. E., Cole, S. W., Weir, D. R., & Crimmins, E. M. (2015) · Social Science & Medicine

Child Abuse and TraumaHealth disparities and outcomes

Cited by 106

Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk

Brandhorst, S., Levine, M. E., Wei, M., Shelehchi, M., Morgan, T. E., Nayak, K. S., Dorff, T., Hong, K., Crimmins, E. M., Cohen, P., et al. (2024) · Nature Communications

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 71

A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin

Levine, M., McDevitt, R. A., Meer, M., Perdue, K., Di Francesco, A., Meade, T., Farrell, C., Thrush, K., Wang, M., Dunn, C., et al. (2020) · eLife

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 52

Changing Disease Prevalence, Incidence, and Mortality Among Older Cohorts: The Health and Retirement Study

Crimmins, E. M., Zhang, Y. S., Kim, J. K., & Levine, M. E. (2019) · The Journals of Gerontology: Series A

Healthcare Systems and Public HealthInsurance, Mortality, Demography, Risk Management

Cited by 37