Bryant, Clare E.

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Mills, E. L., Kelly, B., Logan, A., Costa, A. S. H., Varma, M., Bryant, C. E., Tourlomousis, P., Däbritz, J. H. M., Gottlieb, E., Latorre, I., et al. (2016) · Cell

Immune cells in cancerMitochondrial Function and Pathology

Cited by 2,291

Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms

De, S., Wirthensohn, D. C., Flagmeier, P., Hughes, C., Aprile, F. A., Ruggeri, F. S., Whiten, D. R., Emin, D., Xia, Z., Varela, J. A., et al. (2019) · Nature Communications

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 448

The molecular basis of the host response to lipopolysaccharide

Bryant, C. E., Spring, D. R., Gangloff, M., & Gay, N. J. (2010) · Nature Reviews Microbiology

Immune Response and InflammationInflammasome and immune disorders

Cited by 391

Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis

Castro-Dopico, T., Dennison, T. W., Ferdinand, J. R., Mathews, R. J., Fleming, A., Clift, D., Stewart, B. J., Jing, C., Strongili, K., Labzin, L. I., et al. (2019) · Immunity

Inflammatory Bowel DiseaseGut microbiota and health

Cited by 248

Inflammasome Priming in Sterile Inflammatory Disease

Patel, M. N., Carroll, R. G., Galván-Peña, S., Mills, E. L., Olden, R., Triantafilou, M., Wolf, A. I., Bryant, C. E., Triantafilou, K., & Masters, S. L. (2017) · Trends in Molecular Medicine

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 241

Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis

Hughes, C. D., Choi, M. L., Ryten, M., Hopkins, L., Drews, A., Botía, J. A., Iljina, M., Rodrigues, M., Gagliano, S. A., Gandhi, S., et al. (2019) · Acta Neuropathologica

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 177

Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death

Hughes, C., Choi, M. L., Yi, J.-H., Kim, S.-C., Drews, A., George-Hyslop, P. S., Bryant, C., Gandhi, S., Cho, K., & Klenerman, D. (2020) · Communications Biology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 107

Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses

Meng, J. X., Zhang, Y., Saman, D., Haider, A. M., De, S., Sang, J. C., Brown, K., Jiang, K., Humphrey, J., Julian, L., et al. (2022) · Nature Communications

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 84

Prevention of the foreign body response to implantable medical devices by inflammasome inhibition

Barone, D. G., Carnicer-Lombarte, A., Tourlomousis, P., Hamilton, R. S., Prater, M., Rutz, A. L., Dimov, I. B., Malliaras, G. G., Lacour, S. P., Robertson, A. A. B., et al. (2022) · Proceedings of the National Academy of Sciences

Neuroscience and Neural EngineeringInflammasome and immune disorders

Cited by 67

Gut microbiota-derived hexa-acylated lipopolysaccharides enhance cancer immunotherapy responses

Sardar, P., Beresford-Jones, B. S., Xia, W., Shabana, O., Suyama, S., Ramos, R. J. F., Soderholm, A. T., Tourlomousis, P., Kuo, P., Evans, A. C., et al. (2025) · Nature Microbiology

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 49

Biphasic JNK signaling reveals distinct MAP3K complexes licensing inflammasome formation and pyroptosis

Bradfield, C. J., Liang, J. J., Ernst, O., John, S. P., Sun, J., Ganesan, S., de Jesus, A. A., Bryant, C. E., Goldbach-Mansky, R., & Fraser, I. D. C. (2023) · Cell Death & Differentiation

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 33