Shekhar, Karthik

Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets.

Macosko, E. Z., Basu, A., Satija, R., Nemesh, J., Shekhar, K., Goldman, M., Tirosh, I., Bialas, A. R., Kamitaki, N., Martersteck, E. M., et al. (2015) · Cell

Single-cell and spatial transcriptomicsInnovative Microfluidic and Catalytic Techniques Innovation

Cited by 7,110

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

Villani, A.-C., Satija, R., Reynolds, G., Sarkizova, S., Shekhar, K., Fletcher, J., Griesbeck, M., Butler, A., Zheng, S., Lazo, S., et al. (2017) · Science

Single-cell and spatial transcriptomicsImmunotherapy and Immune Responses

Cited by 2,413

A single-cell survey of the small intestinal epithelium

Haber, A. L., Biton, M., Rogel, N., Herbst, R. H., Shekhar, K., Smillie, C., Burgin, G., Delorey, T. M., Howitt, M. R., Katz, Y., et al. (2017) · Nature

Single-cell and spatial transcriptomicsIL-33, ST2, and ILC Pathways

Cited by 1,750

Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region

Moffitt, J. R., Bambah-Mukku, D., Eichhorn, S. W., Vaughn, E., Shekhar, K., Perez, J. D., Rubinstein, N. D., Hao, J., Regev, A., Dulac, C., et al. (2018) · Science

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 1,365

Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics

Shekhar, K., Lapan, S. W., Whitney, I. E., Tran, N. M., Macosko, E. Z., Kowalczyk, M., Adiconis, X., Levin, J. Z., Nemesh, J., Goldman, M., et al. (2016) · Cell

Single-cell and spatial transcriptomicsRetinal Development and Disorders

Cited by 1,176

Massively parallel single-nucleus RNA-seq with DroNc-seq

Habib, N., Avraham-Davidi, I., Basu, A., Burks, T., Shekhar, K., Hofree, M., Choudhury, S. R., Aguet, F., Gelfand, E., Ardlie, K., et al. (2017) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 1,069

Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis

Farrell, J. A., Wang, Y., Riesenfeld, S. J., Shekhar, K., Regev, A., & Schier, A. F. (2018) · Science

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 876

Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes

Tran, N. M., Shekhar, K., Whitney, I. E., Jacobi, A., Benhar, I., Hong, G., Yan, W., Adiconis, X., Arnold, M. E., Lee, J. M., et al. (2019) · Neuron

Glaucoma and retinal disordersNerve injury and regeneration

Cited by 627

Solving neurodegeneration: common mechanisms and strategies for new treatments

Wareham, L. K., Liddelow, S. A., Temple, S., Benowitz, L. I., Di Polo, A., Wellington, C., Goldberg, J. L., He, Z., Duan, X., Bu, G., et al. (2022) · Molecular Neurodegeneration

Glaucoma and retinal disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 324

Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types

Shekhar, K., Whitney, I. E., Butrus, S., Peng, Y.-R., & Sanes, J. R. (2022) · eLife

Neurogenesis and neuroplasticity mechanismsRetinal Development and Disorders

Cited by 68