Wouters, Jasper

Scenic: single-cell regulatory network inference and clustering.

Aibar, S., González-Blas, C. B., Moerman, T., Huynh-Thu, V. A., Imrichova, H., Hulselmans, G., Rambow, F., Marine, J.-C., Geurts, P., Aerts, J., et al. (2017) · Nature Methods

Single-cell and spatial transcriptomicsGene Regulatory Network Analysis

Cited by 6,520

SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks

Bravo González-Blas, C., De Winter, S., Hulselmans, G., Hecker, N., Matetovici, I., Christiaens, V., Poovathingal, S., Wouters, J., Aibar, S., & Aerts, S. (2023) · Nature Methods

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 778

SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks

González-Blas, C. B., De Winter, S., Hulselmans, G., Hecker, N., Matetovici, I., Christiaens, V., Poovathingal, S., Wouters, J., Aibar, S., & Aerts, S. (2022) · Nature Methods

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 778

cisTopic: cis-regulatory topic modeling on single-cell ATAC-seq data

Bravo González-Blas, C., Minnoye, L., Papasokrati, D., Aibar, S., Hulselmans, G., Christiaens, V., Davie, K., Wouters, J., & Aerts, S. (2019) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 456

Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching

De Smedt, L., Palmans, S., Andel, D., Govaere, O., Boeckx, B., Smeets, D., Galle, E., Wouters, J., Barras, D., Suffiotti, M., et al. (2017) · British Journal of Cancer

Cancer Cells and MetastasisColorectal Cancer Treatments and Studies

Cited by 163

The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes

Jacobs, J., Atkins, M., Davie, K., Imrichova, H., Romanelli, L., Christiaens, V., Hulselmans, G., Potier, D., Wouters, J., Taskiran, I. I., et al. (2018) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 155

Cross-species analysis of enhancer logic using deep learning

Minnoye, L., Taskiran, I. I., Mauduit, D., Fazio, M., Van Aerschot, L., Hulselmans, G., Christiaens, V., Makhzami, S., Seltenhammer, M., Karras, P., et al. (2020) · Genome Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 116

Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation

Varum, S., Baggiolini, A., Zurkirchen, L., Atak, Z. K., Cantù, C., Marzorati, E., Bossart, R., Wouters, J., Häusel, J., Tuncer, E., et al. (2019) · Cell Stem Cell

Developmental Biology and Gene RegulationMelanoma and MAPK Pathways

Cited by 65

High‐throughput sequencing identifies aetiology‐dependent differences in ductular reaction in human chronic liver disease

Govaere, O., Cockell, S., Van Haele, M., Wouters, J., Van Delm, W., Van den Eynde, K., Bianchi, A., van Eijsden, R., Van Steenbergen, W., Monbaliu, D., et al. (2019) · The Journal of Pathology

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 61

Interpretation of allele-specific chromatin accessibility using cell state–aware deep learning

Atak, Z. K., Taskiran, I. I., Demeulemeester, J., Flerin, C., Mauduit, D., Minnoye, L., Hulselmans, G., Christiaens, V., Ghanem, G.-E., Wouters, J., et al. (2021) · Genome Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 48

The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene

van Kempen, L. C. L., Redpath, M., Elchebly, M., Klein, K. O., Papadakis, A. I., Wilmott, J. S., Scolyer, R. A., Edqvist, P.-H., Pontén, F., Schadendorf, D., et al. (2016) · Science Translational Medicine

Cutaneous Melanoma Detection and ManagementGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Cited by 29