Schlake, Thomas

Developing mRNA-vaccine technologies

Schlake, T., Thess, A., Fotin-Mleczek, M., & Kallen, K.-J. (2012) · RNA Biology

RNA Interference and Gene DeliveryImmunotherapy and Immune Responses

Cited by 622

WNT and DKK determine hair follicle spacing through a reaction-diffusion mechanism

Sick, S., Reinker, S., Timmer, J., & Schlake, T. (2006) · Science

Hair Growth and DisordersWnt/β-catenin signaling in development and cancer

Cited by 612

Sequence-engineered mRNA without chemical nucleoside modifications enables an effective protein therapy in large animals

Thess, A., Grund, S., Mui, B. L., Hope, M. J., Baumhof, P., Fotin-Mleczek, M., & Schlake, T. (2015) · Molecular Therapy

RNA Interference and Gene DeliveryRNA and protein synthesis mechanisms

Cited by 513

Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection

Petsch, B., Schnee, M., Vogel, A. B., Lange, E., Hoffmann, B., Voss, D., Schlake, T., Thess, A., Kallen, K.-J., Stitz, L., et al. (2012) · Nature Biotechnology

Influenza Virus Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 464

A novel, disruptive vaccination technology: Self-adjuvanted RNActive ® vaccines

Kallen, K.-J., Heidenreich, R., Schnee, M., Petsch, B., Schlake, T., Thess, A., Baumhof, P., Scheel, B., Koch, S. D., & Fotin-Mleczek, M. (2013) · Human Vaccines & Immunotherapeutics

Immunotherapy and Immune ResponsesRNA Interference and Gene Delivery

Cited by 223

mRNA mediates passive vaccination against infectious agents, toxins, and tumors

Thran, M., Mukherjee, J., Pönisch, M., Fiedler, K., Thess, A., Mui, B. L., Hope, M. J., Tam, Y. K., Horscroft, N., Heidenreich, R., et al. (2017) · EMBO Molecular Medicine

RNA Interference and Gene DeliveryImmunotherapy and Immune Responses

Cited by 166

RNActive® Technology: Generation and Testing of Stable and Immunogenic mRNA Vaccines

Rauch, S., Lutz, J., Kowalczyk, A., Schlake, T., & Heidenreich, R. (2017) · Methods in Molecular Biology

RNA Interference and Gene DeliveryImmunotherapy and Immune Responses

Cited by 57