Bitter, Wilbert

Type VII secretion — mycobacteria show the way

Abdallah, A. M., Gey van Pittius, N. C., DiGiuseppe Champion, P. A., Cox, J., Luirink, J., Vandenbroucke-Grauls, C. M. J. E., Appelmelk, B. J., & Bitter, W. (2007) · Nature Reviews Microbiology

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 763

Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

Simeone, R., Bobard, A., Lippmann, J., Bitter, W., Majlessi, L., Brosch, R., & Enninga, J. (2012) · PLoS Pathogens

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 561

Systematic Genetic Nomenclature for Type VII Secretion Systems

Bitter, W., Houben, E. N. G., Bottai, D., Brodin, P., Brown, E. J., Cox, J. S., Derbyshire, K., Fortune, S. M., Gao, L.-Y., Liu, J., et al. (2009) · PLoS Pathogens

Bacterial Genetics and BiotechnologyEscherichia coli research studies

Cited by 307

Take five — Type VII secretion systems of Mycobacteria

Houben, E. N. G., Korotkov, K. V., & Bitter, W. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 223

Disruption of the ESX‐5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

Bottai, D., Di Luca, M., Majlessi, L., Frigui, W., Simeone, R., Sayes, F., Bitter, W., Brennan, M. J., Leclerc, C., Batoni, G., et al. (2012) · Molecular Microbiology

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 210

Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria

Ates, L. S., Ummels, R., Commandeur, S., van der Weerd, R., Sparrius, M., Weerdenburg, E., Alber, M., Kalscheuer, R., Piersma, S. R., Abdallah, A. M., et al. (2015) · PLOS Genetics

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 185

Composition of the type VII secretion system membrane complex

Houben, E. N. G., Bestebroer, J., Ummels, R., Wilson, L., Piersma, S. R., Jiménez, C. R., Ottenhoff, T. H. M., Luirink, J., & Bitter, W. (2012) · Molecular Microbiology

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 168

The role of transferrin-receptor variation in the host range of Trypanosoma brucei

Bitter, W., Gerrits, H., Kieft, R., & Borst, P. (1998) · Nature

Trypanosoma species research and implicationsResearch on Leishmaniasis Studies

Cited by 149

Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection

Gröschel, M. I., Sayes, F., Shin, S. J., Frigui, W., Pawlik, A., Orgeur, M., Canetti, R., Honoré, N., Simeone, R., van der Werf, T. S., et al. (2017) · Cell Reports

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 125

Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis

Beckham, K. S. H., Ciccarelli, L., Bunduc, C. M., Mertens, H. D. T., Ummels, R., Lugmayr, W., Mayr, J., Rettel, M., Savitski, M. M., Svergun, D. I., et al. (2017) · Nature Microbiology

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 112

Type VII Secretion: A Highly Versatile Secretion System

Ates, L. S., Houben, E. N. G., & Bitter, W. (2016) · Microbiology Spectrum

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 100

Tubercle bacilli rely on a type VII army for pathogenicity

Stoop, E. J. M., Bitter, W., & van der Sar, A. M. (2012) · Trends in Microbiology

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 90

Identification of a Novel Conjugative Plasmid in Mycobacteria That Requires Both Type IV and Type VII Secretion

Ummels, R., Abdallah, A. M., Kuiper, V., Aâjoud, A., Sparrius, M., Naeem, R., Spaink, H. P., van Soolingen, D., Pain, A., & Bitter, W. (2014) · mBio

Bacterial Genetics and BiotechnologyTuberculosis Research and Epidemiology

Cited by 84

Analysis of SecA2-dependent substrates in M ycobacterium marinum identifies protein kinase G (PknG) as a virulence effector: Mycobacterial SecA2 substrates

van der Woude, A. D., Stoop, E. J. M., Stiess, M., Wang, S., Ummels, R., van Stempvoort, G., Piersma, S. R., Cascioferro, A., Jiménez, C. R., Houben, E. N. G., et al. (2014) · Cellular Microbiology

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 64

Animal Models of Tuberculosis: Zebrafish

van Leeuwen, L. M., van der Sar, A. M., & Bitter, W. (2015) · Cold Spring Harbor Perspectives in Medicine

Tuberculosis Research and EpidemiologyZebrafish Biomedical Research Applications

Cited by 53

Structure and Function of the Mycobacterial Type VII Secretion Systems

Bunduc, C. M., Bitter, W., & Houben, E. N. G. (2020) · Annual Review of Microbiology

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 50

Identification of a substrate domain that determines system specificity in mycobacterial type VII secretion systems

Phan, T. H., Ummels, R., Bitter, W., & Houben, E. N. G. (2017) · Scientific Reports

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 41

Protease domain and transmembrane domain of the type VII secretion mycosin protease determine system-specific functioning in mycobacteria

van Winden, V. J. C., Damen, M. P. M., Ummels, R., Bitter, W., & Houben, E. N. G. (2019) · Journal of Biological Chemistry

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 15