Animal Models of Tuberculosis: Zebrafish

The zebrafish reference genome sequence and its relationship to the human genome.

Howe, K., Clark, M. D., Torroja, C. F., Torrance, J., Berthelot, C., Muffato, M., Collins, J. E., Humphray, S., McLaren, K., Matthews, L., et al. (2013) · Nature · doi:10.1038/nature12111 · Cited by 5,100 · see citing works

A transgenic zebrafish model of neutrophilic inflammation

Renshaw, S. A., Loynes, C. A., Trushell, D. M. I., Elworthy, S., Ingham, P. W., & Whyte, M. K. B. (2006) · Blood · doi:10.1182/blood-2006-05-024075 · Cited by 1,013 · see citing works

The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection

Davis, J. M., & Ramakrishnan, L. (2009) · Cell · doi:10.1016/j.cell.2008.11.014 · Cited by 907 · see citing works

Advances in the development of new tuberculosis drugs and treatment regimens

Zumla, A. I., Nahid, P., & Cole, S. T. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd4001 · Cited by 895 · see citing works

Revisiting the role of the granuloma in tuberculosis

Ramakrishnan, L. (2012) · Nature reviews. Immunology · doi:10.1038/nri3211 · Cited by 887 · see citing works

Ontogeny and behaviour of early macrophages in the zebrafish embryo

Herbomel, P., Thisse, B., & Thisse, C. (1999) · Development · doi:10.1242/dev.126.17.3735 · Cited by 799 · see citing works

Headwaters of the zebrafish — emergence of a new model vertebrate

Grunwald, D. J., & Eisen, J. S. (2002) · Nature Reviews Genetics · doi:10.1038/nrg892 · Cited by 735 · see citing works

I mmunity to T uberculosis

North, R. J., & Jung, Y. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.22.012703.104635 · Cited by 677 · see citing works

Development and maturation of the immune system in zebrafish, Danio rerio: a gene expression profiling, in situ hybridization and immunological study

Lam, S. H., Chua, H., Gong, Z., Lam, T. J., & Sin, Y. M. (2003) · Developmental & Comparative Immunology · doi:10.1016/s0145-305x(03)00103-4 · Cited by 610 · see citing works

The Use of Zebrafish to Understand Immunity

Trede, N. S., Langenau, D. M., Traver, D. J., Look, A. T., & Zon, L. I. (2004) · Immunity · doi:10.1016/s1074-7613(04)00084-6 · Cited by 608 · see citing works

Tnf dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species

Roca, F. J., & Ramakrishnan, L. (2013) · Cell · doi:10.1016/j.cell.2013.03.022 · Cited by 592 · see citing works

Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

Tobin, D. M., Roca, F. J., Oh, S. F., McFarland, R., Vickery, T. W., Ray, J. P., Ko, D. C., Zou, Y., Bang, N. D., Chau, T. T. H., et al. (2012) · Cell · doi:10.1016/j.cell.2011.12.023 · Cited by 576 · see citing works

Zebrafish Early Macrophages Colonize Cephalic Mesenchyme and Developing Brain, Retina, and Epidermis through a M-CSF Receptor-Dependent Invasive Process

Herbomel, P., Thisse, B., & Thisse, C. (2001) · Developmental Biology · doi:10.1006/dbio.2001.0393 · Cited by 574 · see citing works

Insights from the complete genome sequence of <i>Mycobacterium marinum</i> on the evolution of <i>Mycobacterium tuberculosis</i>

Stinear, T. P., Seemann, T., Harrison, P. F., Jenkin, G. A., Davies, J. K., Johnson, P. D. R., Abdellah, Z., Arrowsmith, C., Chillingworth, T., Churcher, C., et al. (2008) · Genome Research · doi:10.1101/gr.075069.107 · Cited by 570 · see citing works

Real-Time Visualization of Mycobacterium-Macrophage Interactions Leading to Initiation of Granuloma Formation in Zebrafish Embryos

Davis, J. M., Clay, H., Lewis, J. L., Ghori, N., Herbomel, P., & Ramakrishnan, L. (2002) · Immunity · doi:10.1016/s1074-7613(02)00475-2 · Cited by 565 · see citing works

Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism

Adams, K. N., Takaki, K. K., Connolly, L. E., Wiedenhoft, H., Winglee, K., Humbert, O., Edelstein, P. H., Cosma, C. L., & Ramakrishnan, L. (2011) · Cell · doi:10.1016/j.cell.2011.02.022 · Cited by 522 · see citing works

The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans

Tobin, D. M., Vary, J. C., Ray, J. P., Walsh, G. S., Dunstan, S. J., Bang, N. D., Hagge, D. A., Khadge, S., King, M., Hawn, T. R., et al. (2010) · Cell · doi:10.1016/j.cell.2010.02.013 · Cited by 520 · see citing works

The immunoglobulin heavy-chain locus in zebrafish: identification and expression of a previously unknown isotype, immunoglobulin Z

Danilova, N., Bussmann, J., Howe, K., et al. (2005) · Nature Immunology · doi:10.1038/ni1166 · Cited by 476 · see citing works

Tuberculous Granuloma Induction via Interaction of a Bacterial Secreted Protein with Host Epithelium

Volkman, H. E., Pozos, T. C., Zheng, J., Davis, J. M., Rawls, J. F., & Ramakrishnan, L. (2009) · Science · doi:10.1126/science.1179663 · Cited by 445 · see citing works

New insights into the function of granulomas in human tuberculosis

Ulrichs, T., & Kaufmann, S. H. E. (2006) · Journal of Pathology · doi:10.1002/path.1906 · Cited by 421 · see citing works

ESX‐1‐mediated translocation to the cytosol controls virulence of mycobacteria

Houben, D., Demangel, C., van Ingen, J., Pérez, J., Baldeón, L., Abdallah, A. M., Caleechurn, L., Bottai, D., van Zon, M., de Punder, K., et al. (2012) · Cellular Microbiology · doi:10.1111/j.1462-5822.2012.01799.x · Cited by 415 · see citing works

Towards a new combination therapy for tuberculosis with next generation benzothiazinones

Makarov, V., Lechartier, B., Zhang, M., et al. (2014) · EMBO Molecular Medicine · doi:10.1002/emmm.201303575 · Cited by 383 · see citing works

Origins and unconventional behavior of neutrophils in developing zebrafish

Guyader, D. L., Redd, M. J., Colucci‐Guyon, E., Murayama, E., Kissa, K., Briolat, V., Mordelet, E., Zapata, A. G., Shinomiya, H., & Herbomel, P. (2007) · Blood · doi:10.1182/blood-2007-06-095398 · Cited by 380 · see citing works

Macrophage and T Cell Dynamics during the Development and Disintegration of Mycobacterial Granulomas

Egen, J. G., Rothfuchs, A. G., Feng, C. G., Winter, N., Sher, A., & Germain, R. N. (2008) · Immunity · doi:10.1016/j.immuni.2007.12.010 · Cited by 351 · see citing works

A model 450 million years in the making: zebrafish and vertebrate immunity

Renshaw, S. A., & Trede, N. S. (2012) · Disease Models & Mechanisms · doi:10.1242/dmm.007138 · Cited by 350 · see citing works

Comparative pathogenesis of Mycobacterium marinum and Mycobacterium tuberculosis

Tobin, D. M., & Ramakrishnan, L. (2008) · Cellular Microbiology · doi:10.1111/j.1462-5822.2008.01133.x · Cited by 343 · see citing works

Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo

Bertrand, J. Y., Kim, A. D., Violette, E. P., Stachura, D. L., Schwedler, J. L., & Traver, D. J. (2007) · Development · doi:10.1242/dev.012385 · Cited by 330 · see citing works

Mycobacterium marinum Infection of Adult Zebrafish Causes Caseating Granulomatous Tuberculosis and Is Moderated by Adaptive Immunity

Swaim, L. E., Connolly, L. E., Volkman, H. E., Humbert, O., Born, D. E., & Ramakrishnan, L. (2006) · Infection and Immunity · doi:10.1128/iai.00887-06 · Cited by 329 · see citing works

Immunology and zebrafish: Spawning new models of human disease

Meeker, N. D., & Trede, N. S. (2008) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2007.11.011 · Cited by 311 · see citing works

Tuberculous Granuloma Formation Is Enhanced by a Mycobacterium Virulence Determinant

Volkman, H. E., Clay, H., Beery, D., Chang, J. C., Sherman, D. R., & Ramakrishnan, L. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020367 · Cited by 311 · see citing works

Mycobacterium marinum Escapes from Phagosomes and Is Propelled by Actin-based Motility

Stamm, L. M., Morisaki, J. H., Gao, L., Jeng, R. L., McDonald, K. L., Roth, R. A., Takeshita, S., Heuser, J., Welch, M. D., & Brown, E. J. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20031072 · Cited by 299 · see citing works

Zebrafish: Model for the Study of Inflammation and the Innate Immune Response to Infectious Diseases

Novoa, B., & Figueras, A. J. (2011) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-0106-3_15 · Cited by 297 · see citing works

Neutrophils Exert Protection in the Early Tuberculous Granuloma by Oxidative Killing of Mycobacteria Phagocytosed from Infected Macrophages

Yang, C.-T., Cambier, C. J., Davis, J. M., Hall, C. J., Crosier, P. S., & Ramakrishnan, L. (2012) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2012.07.009 · Cited by 293 · see citing works

The Zebrafish as a Model Organism to Study Development of the Immune System

Traver, D. J., Herbomel, P., Patton, E. E., Murphey, R. D., Yoder, J. A., Litman, G. W., Catic, A., Amemiya, C. T., Zon, L. I., & Trede, N. S. (2003) · Advances in immunology · doi:10.1016/s0065-2776(03)81007-6 · Cited by 273 · see citing works

Identification of dendritic antigen-presenting cells in the zebrafish

Lugo‐Villarino, G., Balla, K. M., Stachura, D. L., Bañuelos, K., Werneck, M. B. F., & Traver, D. J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000494107 · Cited by 267 · see citing works

Host-Pathogen Interactions Made Transparent with the Zebrafish Model

Meijer, A. H., & Spaink, H. P. (2011) · Current Drug Targets · doi:10.2174/138945011795677809 · Cited by 253 · see citing works

Mutagenesis strategies in zebrafish for identifying genes involved in development and disease

Amsterdam, A., & Hopkins, N. (2006) · Trends in Genetics · doi:10.1016/j.tig.2006.06.011 · Cited by 251 · see citing works

Dichotomous Role of the Macrophage in Early Mycobacterium marinum Infection of the Zebrafish

Clay, H., Davis, J. M., Beery, D., Anna Huttenlocher, A., Lyons, S. E., & Ramakrishnan, L. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2007.06.004 · Cited by 243 · see citing works

Infection of Zebrafish Embryos with Intracellular Bacterial Pathogens

Benard, E. L., van der Sar, A. M., Ellett, F. E., et al. (2012) · Journal of Visualized Experiments · doi:10.3791/3781 · Cited by 235 · see citing works

Host–microbe interactions in the developing zebrafish

Kanther, M., & Rawls, J. F. (2010) · Current Opinion in Immunology · doi:10.1016/j.coi.2010.01.006 · Cited by 229 · see citing works

An evolutionarily conserved program of B-cell development and activation in zebrafish

Page, D. M., Wittamer, V., Bertrand, J., et al. (2013) · Blood · doi:10.1182/blood-2012-12-471029 · Cited by 220 · see citing works

Deep sequencing of the zebrafish transcriptome response to mycobacterium infection

Hegedűs, Z., Zakrzewska, A., Ágoston, V. C., Ordas, A., Rácz, P., Mink, M., Spaink, H. P., & Meijer, A. H. (2009) · Molecular Immunology · doi:10.1016/j.molimm.2009.07.002 · Cited by 216 · see citing works

A star with stripes: zebrafish as an infection model

van der Sar, A. M., Appelmelk, B. J., Vandenbroucke‐Grauls, C. M. J. E., & Bitter, W. (2004) · Trends in Microbiology · doi:10.1016/j.tim.2004.08.001 · Cited by 216 · see citing works

Real-Time Whole-Body Visualization of Chikungunya Virus Infection and Host Interferon Response in Zebrafish

Palha, N., Guivel‐Benhassine, F., Briolat, V., Lutfalla, G., Sourisseau, M., Ellett, F. E., Wang, C., Lieschke, G. J., Herbomel, P., Schwartz, O., et al. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003619 · Cited by 202 · see citing works

Attenuation of Virulence by Disruption of the Mycobacterium tuberculosis erp Gene

Berthet, F., Lagranderie, M., Gounon, P., Laurent‐Winter, C., Ensergueix, D., Chavarot, P., Thouron, F., Maranghi, E., Pelicic, V., Portnoi, D., et al. (1998) · Science · doi:10.1126/science.282.5389.759 · Cited by 202 · see citing works

Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants

Balla, K. M., Lugo‐Villarino, G., Spitsbergen, J. M., et al. (2010) · Blood · doi:10.1182/blood-2010-03-267419 · Cited by 195 · see citing works

Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens

Lin, P. L., Coleman, T., Carney, J., et al. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00277-13 · Cited by 191 · see citing works

Pathogen Recognition and Activation of the Innate Immune Response in Zebrafish

van der Vaart, M., Spaink, H. P., & Meijer, A. H. (2012) · Advances in Hematology · doi:10.1155/2012/159807 · Cited by 172 · see citing works

Zebrafish development and regeneration: new tools for biomedical research

Brittijn, S. A., van der Plas-Duivesteijn, S. J., Belmamoune, M., Bertens, L. M. F., Bitter, W., de Bruijn, J. D., Champagne, D. L., Cuppen, E. P. J. G., Flik, G., Vandenbroucke‐Grauls, C. M. J. E., et al. (2009) · The International Journal of Developmental Biology · doi:10.1387/ijdb.082615sb · Cited by 164 · see citing works

Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

Elks, P. M., Brizee, S., van der Vaart, M., Walmsley, S. R., van Eeden, F. J., Renshaw, S. A., & Meijer, A. H. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003789 · Cited by 143 · see citing works

Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection

Meijer, A. H., Verbeek, F. J., Vidal, E. S., Corredor-Adámez, M., Bussman, J., van der Sar, A. M., Otto, G., Geisler, R., & Spaink, H. P. (2005) · Molecular Immunology · doi:10.1016/j.molimm.2004.11.014 · Cited by 142 · see citing works

Functional analysis of a zebrafishmyd88mutant identifies key transcriptional components of the innate immune system

van der Vaart, M., van Soest, J. J., Spaink, H. P., & Meijer, A. H. (2013) · Disease Models & Mechanisms · doi:10.1242/dmm.010843 · Cited by 134 · see citing works

Carboxypeptidase A5 identifies a novel mast cell lineage in the zebrafish providing new insight into mast cell fate determination

Dobson, J. T., Seibert, J., Teh, E., et al. (2008) · Blood · doi:10.1182/blood-2008-03-145011 · Cited by 133 · see citing works

Mycobacterium marinum Causes a Latent Infection that Can Be Reactivated by Gamma Irradiation in Adult Zebrafish

Parikka, M., Hammarén, M. M., Harjula, S.-K. E., Halfpenny, N. J. A., Oksanen, K. E., Lahtinen, M. J., Pajula, E. T., Iivanainen, A., Pesu, M., & Rämet, M. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002944 · Cited by 130 · see citing works

Mycobacterium marinum Strains Can Be Divided into Two Distinct Types Based on Genetic Diversity and Virulence

van der Sar, A. M., Abdallah, A. M., Sparrius, M., Reinders, E., Vandenbroucke‐Grauls, C. M. J. E., & Bitter, W. (2004) · Infection and Immunity · doi:10.1128/iai.72.11.6306-6312.2004 · Cited by 127 · see citing works

Conserved Functions of Ikaros in Vertebrate Lymphocyte Development: Genetic Evidence for Distinct Larval and Adult Phases of T Cell Development and Two Lineages of B Cells in Zebrafish

Schorpp, M., Bialecki, M., Diekhoff, D., Walderich, B., Odenthal, J., Maischein, H., Zapata, A. G., Freiburg Screening Group, & Boehm, T. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.4.2463 · Cited by 122 · see citing works

Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components

van der Sar, A. M., Spaink, H. P., Zakrzewska, A., Bitter, W., & Meijer, A. H. (2009) · Molecular Immunology · doi:10.1016/j.molimm.2009.03.024 · Cited by 120 · see citing works

Fish T cells: Recent advances through genomics

Laing, K. J., & Hansen, J. D. (2011) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2011.03.004 · Cited by 118 · see citing works

T cells and the thymus in developing zebrafish

Danilova, N. (2004) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2003.12.003 · Cited by 104 · see citing works

Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component

Stoop, E. J. M., Schipper, T., Huber, S. K. R., Nezhinsky, A. E., Verbeek, F. J., Gurcha, S. S., Besra, G. S., Vandenbroucke‐Grauls, C. M. J. E., Bitter, W., & van der Sar, A. M. (2011) · Disease Models & Mechanisms · doi:10.1242/dmm.006676 · Cited by 104 · see citing works

The CRISPR System—Keeping Zebrafish Gene Targeting Fresh

Blackburn, P. R., Campbell, J. M., Clark, K. J., & Ekker, S. C. (2013) · Zebrafish · doi:10.1089/zeb.2013.9999 · Cited by 101 · see citing works

The histopathologic spectrum in Mycobacterium marinum infection.

Wd, T., Travis, L. B., Gd, R., et al. (1985) · PubMed · Cited by 100 · see citing works

A Mycobacterial Operon Essential for Virulence In Vivo and Invasion and Intracellular Persistence in Macrophages

Gao, L., Pak, M. A., Kish, R., Kajihara, K. K., & Brown, E. J. (2006) · Infection and Immunity · doi:10.1128/iai.74.3.1757-1767.2006 · Cited by 100 · see citing works

New models for the study of Mycobacterium–host interactions

Pozos, T. C., & Ramakrishnan, L. (2004) · Current Opinion in Immunology · doi:10.1016/j.coi.2004.05.011 · Cited by 100 · see citing works

Robotic injection of zebrafish embryos for high-throughput screening in disease models

Spaink, H. P., Cui, C., Wiweger, M. I. K. N., Jansen, H. J., Veneman, W. J., Marín‐Juez, R., de Sonneville, J., Ordas, A., Torraca, V., van der Ent, W., et al. (2013) · Methods · doi:10.1016/j.ymeth.2013.06.002 · Cited by 99 · see citing works

Tuberculosis: A Comprehensive Clinical Reference

Schaaf, H. S., & Zumla, A. I. (2009) · Cited by 96 · see citing works

A Mycobacterium marinum TesA mutant defective for major cell wall‐associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos

Alibaud, L., Rombouts, Y., Trivelli, X., Burguière, A., Cirillo, S. L. G., Cirillo, J. D., Dubremetz, J., Guérardel, Y., Lutfalla, G., & Kremer, L. (2011) · Molecular Microbiology · doi:10.1111/j.1365-2958.2011.07618.x · Cited by 95 · see citing works

Cutaneous tuberculosis

MacGregor, R. R. (1995) · Clinics in Dermatology · doi:10.1016/0738-081x(95)00019-c · Cited by 94 · see citing works

Transposon Mutagenesis ofMycobacterium marinumIdentifies a Locus Linking Pigmentation and Intracellular Survival

Gao, L., Groger, R. K., Cox, J. S., Beverley, S. M., Lawson, E. H., & Brown, E. J. (2003) · Infection and Immunity · doi:10.1128/iai.71.2.922-929.2003 · Cited by 93 · see citing works

Mycobacterium marinum Erp Is a Virulence Determinant Required for Cell Wall Integrity and Intracellular Survival

Cosma, C. L., Klein, K. A., Kim, R., Beery, D., & Ramakrishnan, L. (2006) · Infection and Immunity · doi:10.1128/iai.02061-05 · Cited by 92 · see citing works

Tubercle bacilli rely on a type VII army for pathogenicity

Stoop, E. J. M., Bitter, W., & van der Sar, A. M. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.07.001 · Cited by 90 · see citing works

Insights into early mycobacterial pathogenesis from the zebrafish

Lesley, R., & Ramakrishnan, L. (2008) · Current Opinion in Microbiology · doi:10.1016/j.mib.2008.05.013 · Cited by 88 · see citing works

Morphologic transformation of the thymus in developing zebrafish

Lam, S. H., Chua, H., Gong, Z., Wen, Z., Lam, T. J., & Sin, Y. M. (2002) · Developmental Dynamics · doi:10.1002/dvdy.10127 · Cited by 86 · see citing works

Experimental exposure of zebrafish, Danio rerio (Hamilton), to Mycobacterium marinum and Mycobacterium peregrinum reveals the gastrointestinal tract as the primary route of infection: a potential model for environmental mycobacterial infection

Harriff, M. J., Bermudez, L. E., & Kent, M. L. (2007) · Journal of Fish Diseases · doi:10.1111/j.1365-2761.2007.00839.x · Cited by 85 · see citing works

Mannan Chain Length Controls Lipoglycans Signaling via and Binding to TLR2

Nigou, J., Vasselon, T., Ray, A. A., Constant, P., Gilleron, M., Besra, G. S., Sutcliffe, I. C., Tiraby, G., & Puzo, G. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.10.6696 · Cited by 81 · see citing works

Pathogenesis of Mycobacterium spp. in zebrafish (Danio rerio) from research facilities

Watral, V. G., & Kent, M. L. (2006) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2006.06.004 · Cited by 79 · see citing works

An adult zebrafish model for preclinical tuberculosis vaccine development

Oksanen, K. E., Halfpenny, N. J. A., Sherwood, E., Harjula, S.-K. E., Hammarén, M. M., Ahava, M. J., Pajula, E. T., Lahtinen, M. J., Parikka, M., & Rämet, M. (2013) · Vaccine · doi:10.1016/j.vaccine.2013.08.093 · Cited by 75 · see citing works

The Granuloma in Tuberculosis — Friend or Foe?

Rubin, E. J. (2009) · New England Journal of Medicine · doi:10.1056/nejmcibr0902539 · Cited by 72 · see citing works

Looking Within the Zebrafish to Understand the Tuberculous Granuloma

Ramakrishnan, L. (2013) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-6111-1_13 · Cited by 72 · see citing works

ESX-5-deficient Mycobacterium marinum is hypervirulent in adult zebrafish

Weerdenburg, E. M., Abdallah, A. M., Mitra, S., de Punder, K., van der Wel, N. N., Bird, S., Appelmelk, B. J., Bitter, W., & van der Sar, A. M. (2012) · Cellular Microbiology · doi:10.1111/j.1462-5822.2012.01755.x · Cited by 67 · see citing works

Analysis of SecA2-dependent substrates in <i>M</i> <i>ycobacterium marinum</i> identifies protein kinase G (PknG) as a virulence effector: Mycobacterial SecA2 substrates

van der Woude, A. D., Stoop, E. J. M., Stiess, M., Wang, S., Ummels, R., van Stempvoort, G., Piersma, S. R., Cascioferro, A., Jiménez, C. R., Houben, E. N. G., et al. (2014) · Cellular Microbiology · doi:10.1111/cmi.12221 · Cited by 64 · see citing works

Infection of Zebrafish Embryos with Intracellular Bacterial Pathogens

Benard, E. L., van der Sar, A. M., Ellett, F. E., et al. (2012) · Journal of Visualized Experiments · doi:10.3791/3781-v · Cited by 60 · see citing works

Insights into tuberculosis from the zebrafish model

Berg, R. D., & Ramakrishnan, L. (2012) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2012.10.002 · Cited by 56 · see citing works

Paramecium caudatum enhances transmission and infectivity of Mycobacterium marinum and M. chelonae in zebrafish Danio rerio

Peterson, T., Ferguson, J., Watral, V. G., Mutoji, K. N., Ennis, D., & Kent, M. (2013) · Diseases of Aquatic Organisms · doi:10.3354/dao02649 · Cited by 55 · see citing works

Form, function and phylogenetics of NITRs in bony fish

Yoder, J. A. (2008) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2008.09.004 · Cited by 54 · see citing works

Deficiency in Hematopoietic Phosphatase Ptpn6/Shp1 Hyperactivates the Innate Immune System and Impairs Control of Bacterial Infections in Zebrafish Embryos

Kanwal, Z., Zakrzewska, A., den Hertog, J., Spaink, H. P., Schaaf, M. J. M., & Meijer, A. H. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1200551 · Cited by 51 · see citing works

Unexpected Link between Lipooligosaccharide Biosynthesis and Surface Protein Release in Mycobacterium marinum

van der Woude, A. D., Sarkar, D., Bhatt, A., Sparrius, M., Raadsen, S. A., Boon, L., Geurtsen, J., van der Sar, A. M., Luirink, J., Houben, E. N. G., et al. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.336461 · Cited by 47 · see citing works

Characterization of the zebrafish T cell receptor β locus

Meeker, N. D., Smith, A. C. H., Frazer, J. K., et al. (2010) · Immunogenetics · doi:10.1007/s00251-009-0407-6 · Cited by 45 · see citing works

Biochemical, molecular, and virulence characteristics of select Mycobacterium marinum isolates in hybrid striped bass Morone chrysops × M. saxatilis and zebrafish Danio rerio

Ostland, V., Watral, V. G., Whipps, C. M., Austin, F., St‐Hilaire, S., Westerman, M., & Kent, M. (2008) · Diseases of Aquatic Organisms · doi:10.3354/dao01891 · Cited by 44 · see citing works

Developmental and tissue-specific expression of NITRs

Yoder, J. A., Turner, P. M., Wright, P. D., et al. (2009) · Immunogenetics · doi:10.1007/s00251-009-0416-5 · Cited by 44 · see citing works

Characterization of immune-matched hematopoietic transplantation in zebrafish

de Jong, J. L. O., Burns, C. E., Chen, A. T., Pugach, E. K., Mayhall, E. A., Smith, A. C. H., Feldman, H. A., Zhou, Y., & Zon, L. I. (2011) · Blood · doi:10.1182/blood-2010-09-307488 · Cited by 41 · see citing works

Tuberculosis: A Comprehensive Clinical Reference

Obeid, K. M. (2009) · JAMA · doi:10.1001/jama.2009.1815 · Cited by 38 · see citing works

Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity

Stoop, E. J. M., Mishra, A. K., Driessen, N. N., van Stempvoort, G., Bouchier, P., Verboom, T., van Leeuwen, L. M., Sparrius, M., Raadsen, S. A., van Zon, M., et al. (2013) · Cellular Microbiology · doi:10.1111/cmi.12175 · Cited by 32 · see citing works

Use of mouse models to study the variability in virulence associated with specific genotypic lineages of Mycobacterium tuberculosis

Hernández‐Pando, R., Marquina‐Castillo, B., Barrios‐Payán, J., & Mata‐Espinosa, D. (2012) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2012.02.013 · Cited by 30 · see citing works

In vivo and in vitro growth of Mycobacterium marinum at homoeothermic temperatures

Kent, M. L., Watral, V. G., Wu, M., et al. (2006) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2006.00173.x · Cited by 28 · see citing works

Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism

Adams, K. N., Takaki, K. K., Connolly, L. E., et al. (2011) · Cell · doi:10.1016/j.cell.2011.03.017 · Cited by 27 · see citing works

Tuberculous Granuloma Induction via Interaction of a Bacterial Secreted Protein with Host Epithelium

Pozos, T. C., Ramakrishnan, L., Volkman, H. E., et al. (2020) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/ka79-1117 · Cited by 20 · see citing works

IMMUNITY TO TUBERCULOSIS

HEIMBECK, J. (1932) · Archives of Internal Medicine · doi:10.1001/archinte.1932.00150130080006 · Cited by 19 · see citing works

Histocompatibility and Hematopoietic Transplantation in the Zebrafish

de Jong, J. L. O., & Zon, L. I. (2012) · Advances in Hematology · doi:10.1155/2012/282318 · Cited by 15 · see citing works

Directly Observing Therapy: A New View of Drug Tolerance in Tuberculosis

Philips, J. A., & Ernst, J. (2011) · Cell · doi:10.1016/j.cell.2011.02.041 · Cited by 6 · see citing works

Mycobacterium smegmatis: The Vanguard of Mycobacterial Research

Sparks, I. L., Derbyshire, K. M., Jacobs, W. R., & Morita, Y. S. (2023) · Journal of Bacteriology · doi:10.1128/jb.00337-22 · Cited by 149 · see citing works

Zebrafish (Danio rerio) as a Model Organism

Khan, F. R., & Alhewairini, S. S. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.81517 · Cited by 39 · see citing works

Zebrafish in Biomedical Research and Drug Discovery

Maddula, K., & Juluru, A. (2016) · Research and reviews : journal of pharmacology and toxicological studies · Cited by 2 · see citing works

Introductory Chapter: Importance of Zebrafish (Danio rerio) as Model Organism in Biomedical Research

Bozkurt, Y. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.91319

Zebrafish (Danio rerio) as a Model Organism for Dementia

Willemsen, R., Padje, S. V. ‘., Swieten, J. C. V., & Oostra, B. A. (2010) · Neuromethods · doi:10.1007/978-1-60761-898-0_14 · Cited by 11 · see citing works

Inverse correlation between salt tolerance and host-adaptation in mycobacteria

Asmar, S., Sassi, M., Phelippeau, M., et al. (2016) · BMC Research Notes · doi:10.1186/s13104-016-2054-y · Cited by 20 · see citing works