Casarotto, Plinio C.

Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

Casarotto, P. C., Girych, M., Fred, S. M., Kovaleva, V., Moliner, R., Enkavi, G., Biojone, C., Cannarozzo, C., Sahu, M. P., Kaurinkoski, K., et al. (2021) · Cell

Treatment of Major DepressionNerve injury and regeneration

Cited by 663

Psychedelics promote plasticity by directly binding to BDNF receptor TrkB

Moliner, R., Girych, M., Brunello, C. A., Kovaleva, V., Biojone, C., Enkavi, G., Antenucci, L., Kot, E. F., Goncharuk, S. A., Kaurinkoski, K., et al. (2023) · Nature Neuroscience

Psychedelics and Drug StudiesTreatment of Major Depression

Cited by 478

Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors

Casarotto, P. C., Gomes, F. V., Resstel, L. B. M., & Guimarães, F. S. (2010) · Behavioural Pharmacology

Cannabis and Cannabinoid ResearchMedicinal Plant Extracts Effects

Cited by 141

Isoflurane produces antidepressant effects and induces TrkB signaling in rodents

Antila, H., Ryazantseva, M., Popova, D., Sipilä, P., Guirado, R., Kohtala, S., Yalcin, I., Lindholm, J., Vesa, L., Sato, V., et al. (2017) · Scientific Reports

Treatment of Major DepressionAnesthesia and Neurotoxicity Research

Cited by 84

Antidepressant- and anticompulsive-like effects of purinergic receptor blockade: Involvement of nitric oxide

Pereira, V. S., Casarotto, P. C., Hiroaki-Sato, V. A., Sartim, A. G., Guimarães, F. S., & Joca, S. R. L. (2013) · European Neuropsychopharmacology

Adenosine and Purinergic SignalingNeurotransmitter Receptor Influence on Behavior

Cited by 66

Beyond good and evil: A putative continuum-sorting hypothesis for the functional role of proBDNF/BDNF-propeptide/mBDNF in antidepressant treatment

Diniz, C. R. A. F., Casarotto, P. C., Resstel, L., & Joca, S. R. L. (2018) · Neuroscience & Biobehavioral Reviews

Nerve injury and regenerationTreatment of Major Depression

Cited by 58

Chondroitinase and Antidepressants Promote Plasticity by Releasing TRKB from Dephosphorylating Control of PTPσ in Parvalbumin Neurons

Lesnikova, A., Casarotto, P. C., Fred, S. M., Voipio, M., Winkel, F., Steinzeig, A., Antila, H., Umemori, J., Biojone, C., & Castrén, E. (2021) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 56

Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2

Fred, S. M., Laukkanen, L., Brunello, C. A., Vesa, L., Göös, H., Cardon, I., Moliner, R., Maritzen, T., Varjosalo, M., Casarotto, P. C., et al. (2019) · Journal of Biological Chemistry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 52

Reduced P2X receptor levels are associated with antidepressant effect in the learned helplessness model

Ribeiro, D. E., Casarotto, P. C., Staquini, L., Pinto e Silva, M. A., Biojone, C., Wegener, G., & Joca, S. (2019) · PeerJ

Adenosine and Purinergic SignalingTreatment of Major Depression

Cited by 21

Perineuronal Net Receptor PTPσ Regulates Retention of Memories

Lesnikova, A., Casarotto, P., Moliner, R., Fred, S. M., Biojone, C., & Castrén, E. (2021) · Frontiers in Synaptic Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 21

Urokinase plasminogen activator mediates changes in human astrocytes modeling fragile X syndrome

Peteri, U., Pitkonen, J., de Toma, I., Nieminen, O., Utami, K. H., Strandin, T. M., Corcoran, P., Roybon, L., Vaheri, A., Ethell, I., et al. (2021) · Glia

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 16

P2X7 receptors are involved in stress-related behaviours and antidepressant effect

Ribeiro, D. E., Stanquini, L. A., Biojone, C., Casarotto, P. C., Elfving, B., Müller, H. K., Wegener, G., & Joca, S. R. L. (2019) · European Neuropsychopharmacology

Adenosine and Purinergic SignalingNeurotransmitter Receptor Influence on Behavior

Cited by 11

Ketamine and its metabolite 2R,6R-hydroxynorketamine promote ocular dominance plasticity and release TRKB from inhibitory control without changing perineuronal nets enwrapping parvalbumin interneurons

Cannarozzo, C., Rubiolo, A., Casarotto, P., & Castrén, E. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 2