Hendriks, Delilah F. G.

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Bell, C. C., Hendriks, D. F. G., Moro, S. M. L., Ellis, E., Walsh, J., Renblom, A., Fredriksson Puigvert, L., Dankers, A. C. A., Jacobs, F., Snoeys, J., et al. (2016) · Scientific Reports

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 739

Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids

Marsee, A., Roos, F. J. M., Verstegen, M. M. A., Marsee, A., Roos, F., Verstegen, M., Clevers, H., Vallier, L., Takebe, T., Huch, M., et al. (2021) · Cell Stem Cell

3D Printing in Biomedical ResearchPancreatic function and diabetes

Cited by 310

Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates

Lauschke, V. M., Hendriks, D. F. G., Bell, C. C., Andersson, T. B., & Ingelman-Sundberg, M. (2016) · Chemical Research in Toxicology

Drug-Induced Hepatotoxicity and Protection3D Printing in Biomedical Research

Cited by 241

Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability

Hendriks, D. F. G., Fredriksson Puigvert, L., Messner, S., Mortiz, W., & Ingelman-Sundberg, M. (2016) · Scientific Reports

Drug-Induced Hepatotoxicity and ProtectionDrug Transport and Resistance Mechanisms

Cited by 156

3D Primary Hepatocyte Culture Systems for Analyses of Liver Diseases, Drug Metabolism, and Toxicity: Emerging Culture Paradigms and Applications

Lauschke, V. M., Shafagh, R. Z., Hendriks, D. F. G., & Ingelman‐Sundberg, M. (2019) · Biotechnology Journal

3D Printing in Biomedical ResearchDrug-Induced Hepatotoxicity and Protection

Cited by 153

Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation

Lauschke, V. M., Vorrink, S. U., Moro, S. M. L., Rezayee, F., Nordling, Å., Hendriks, D. F. G., Bell, C. C., Sison‐Young, R., Park, B. K., Goldring, C. E., et al. (2016) · Hepatology

Liver physiology and pathologyMicroRNA in disease regulation

Cited by 121

In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed

Bonanini, F., Kurek, D., Previdi, S., Nicolas, A., Hendriks, D., de Ruiter, S., Meyer, M., Clapés Cabrer, M., Dinkelberg, R., García, S. B., et al. (2022) · Angiogenesis

3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Cited by 112

One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids

Geurts, M. H., Gandhi, S., Boretto, M. G., Akkerman, N., Derks, L. L. M., van Son, G., Celotti, M., Harshuk-Shabso, S., Peci, F., Begthel, H., et al. (2023) · Nature Communications

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 66

Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three‐Dimensional Spheroid Cultures of Primary Human Hepatocytes

Hendriks, D. F. G., Vorrink, S. U., Smutny, T., Sim, S. C., Nordling, Å., Ullah, S., Kumondai, M., Jones, B. C., Johansson, I., Andersson, T. B., et al. (2020) · Clinical Pharmacology & Therapeutics

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 57

Mechanisms of Chronic Fialuridine Hepatotoxicity as Revealed in Primary Human Hepatocyte Spheroids

Hendriks, D. F. G., Hurrell, T., Riede, J., van der Horst, M., Tuovinen, S., & Ingelman-Sundberg, M. (2019) · Toxicological Sciences

Drug-Induced Hepatotoxicity and ProtectionAnimal testing and alternatives

Cited by 29

Nanoblades allow high-level genome editing in murine and human organoids

Tiroille, V., Krug, A., Bokobza, E., Kahi, M., Bulcaen, M., Ensinck, M. M., Geurts, M. H., Hendriks, D., Vermeulen, F., Larbret, F., et al. (2023) · Molecular Therapy - Nucleic Acids

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 25