Phillips, Michael C.

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

Musunuru, K., Strong, A., Frank-Kamenetsky, M., Lee, N. E., Ahfeldt, T., Sachs, K. V., Li, X., Li, H., Kuperwasser, N., Ruda, V. M., et al. (2010) · Nature

Genetic Associations and EpidemiologyCholesterol and Lipid Metabolism

Cited by 1,140

Cholesterol Efflux and Atheroprotection: Advancing the Concept of Reverse Cholesterol Transport

Rosenson, R. S., Brewer, H. B., Davidson, W. S., Fayad, Z. A., Fuster, V., Goldstein, J., Hellerstein, M., Jiang, X.-C., Phillips, M. C., Rader, D. J., et al. (2012) · Circulation

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 953

Apolipoprotein E isoforms and lipoprotein metabolism

Phillips, M. C. (2014) · IUBMB Life

Lipid metabolism and disordersLipoproteins and Cardiovascular Health

Cited by 328

Differences in stability among the human apolipoprotein E isoforms determined by the amino-terminal domain

Morrow, J. A., Segall, M. L., Lund-Katz, S., Phillips, M. C., Knapp, M., Rupp, B., & Weisgraber, K. H. (2000) · Biochemistry

Protein Structure and DynamicsAlzheimer's disease research and treatments

Cited by 315

Class B Scavenger Receptor-Mediated Intestinal Absorption of Dietary β-Carotene and Cholesterol

van Bennekum, A., Werder, M., Thuahnai, S. T., Han, C.-H., Duong, P., Williams, D. L., Wettstein, P., Schulthess, G., Phillips, M. C., & Hauser, H. (2005) · Biochemistry

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 290

High Density Lipoprotein Structure–Function and Role in Reverse Cholesterol Transport

Lund-Katz, S., & Phillips, M. C. (2010) · Subcellular Biochemistry

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 262

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

Strong, A., Ding, Q., Edmondson, A. C., Millar, J. S., Sachs, K. V., Li, X., Kumaravel, A., Wang, M. Y., Ai, D., Guo, L., et al. (2012) · Journal of Clinical Investigation

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 222

New Insights into the Heparan Sulfate Proteoglycan-binding Activity of Apolipoprotein E

Libeu, C. P., Lund-Katz, S., Phillips, M. C., Wehrli, S., Hernáiz, M. J., Capila, I., Linhardt, R. J., Raffaı̈, R. L., Newhouse, Y. M., Zhou, F., et al. (2001) · Journal of Biological Chemistry

Proteoglycans and glycosaminoglycans researchAlzheimer's disease research and treatments

Cited by 113

Lipid Binding-induced Conformational Change in Human Apolipoprotein E

Saito, H., Dhanasekaran, P., Baldwin, F., Weisgraber, K. H., Lund-Katz, S., & Phillips, M. C. (2001) · Journal of Biological Chemistry

Lipid Membrane Structure and BehaviorProtein Interaction Studies and Fluorescence Analysis

Cited by 113

Effect of dietary supplementation with n-3 polyunsaturated fatty acids on physical properties and metabolism of low density lipoprotein in humans.

Nenseter, M. S., Rustan, A. C., Lund-Katz, S., Søyland, E., Maelandsmo, G., Phillips, M. C., & Drevon, C. A. (1992) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology

Fatty Acid Research and HealthCholesterol and Lipid Metabolism

Cited by 99

Two-step Mechanism of Binding of Apolipoprotein E to Heparin

Futamura, M., Dhanasekaran, P., Handa, T., Phillips, M. C., Lund-Katz, S., & Saito, H. (2005) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 91

Characterization of the Heparin Binding Sites in Human Apolipoprotein E

Saito, H., Dhanasekaran, P., Nguyen, D., Baldwin, F., Weisgraber, K. H., Wehrli, S., Phillips, M. C., & Lund-Katz, S. (2003) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 90

Mechanism underlying apolipoprotein E (ApoE) isoform‐dependent lipid efflux from neural cells in culture

Minagawa, H., Gong, J., Jung, C., Watanabe, A., Lund‐Katz, S., Phillips, M. C., Saito, H., & Michikawa, M. (2009) · Journal of Neuroscience Research

Cholesterol and Lipid MetabolismAlzheimer's disease research and treatments

Cited by 90

Molecular Basis for the Differences in Lipid and Lipoprotein Binding Properties of Human Apolipoproteins E3 and E4

Nguyen, D., Dhanasekaran, P., Nickel, M., Nakatani, R., Saito, H., Phillips, M. C., & Lund-Katz, S. (2010) · Biochemistry

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 89

Effects of Polymorphism on the Lipid Interaction of Human Apolipoprotein E

Saito, H., Dhanasekaran, P., Baldwin, F., Weisgraber, K. H., Phillips, M. C., & Lund-Katz, S. (2003) · Journal of Biological Chemistry

Lipid Membrane Structure and BehaviorLipoproteins and Cardiovascular Health

Cited by 89

Comparison of the stabilities and unfolding pathways of human apolipoprotein E isoforms by differential scanning calorimetry and circular dichroism.

Acharya, P., Segall, M. L., Zaiou, M., Morrow, J., Weisgraber, K. H., Phillips, M. C., Lund-Katz, S., & Snow, J. (2002) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Protein Structure and DynamicsAlzheimer's disease research and treatments

Cited by 82

A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state

Melchior, J. T., Walker, R. G., Cooke, A. L., Morris, J., Castleberry, M., Thompson, T. B., Jones, M. K., Song, H. D., Rye, K.-A., Oda, M. N., et al. (2017) · Nature Structural & Molecular Biology

Protein Structure and DynamicsCholesterol and Lipid Metabolism

Cited by 71

Helical structure, stability, and dynamics in human apolipoprotein E3 and E4 by hydrogen exchange and mass spectrometry

Chetty, P. S., Mayne, L., Lund-Katz, S., Englander, S. W., & Phillips, M. C. (2017) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsMass Spectrometry Techniques and Applications

Cited by 58

Contributions of the Carboxyl-Terminal Helical Segment to the Self-Association and Lipoprotein Preferences of Human Apolipoprotein E3 and E4 Isoforms

Sakamoto, T., Tanaka, M., Vedhachalam, C., Nickel, M., Nguyen, D., Dhanasekaran, P., Phillips, M. C., Lund-Katz, S., & Saito, H. (2008) · Biochemistry

Cholesterol and Lipid MetabolismLipid Membrane Structure and Behavior

Cited by 54

Role of the N- and C-Terminal Domains in Binding of Apolipoprotein E Isoforms to Heparan Sulfate and Dermatan Sulfate: A Surface Plasmon Resonance Study

Yamauchi, Y., Deguchi, N., Takagi, C., Tanaka, M., Dhanasekaran, P., Nakano, M., Handa, T., Phillips, M. C., Lund-Katz, S., & Saito, H. (2008) · Biochemistry

Proteoglycans and glycosaminoglycans researchAlzheimer's disease research and treatments

Cited by 53

Apolipoprotein A-I-stimulated Apolipoprotein E Secretion from Human Macrophages Is Independent of Cholesterol Efflux

Kockx, M., Rye, K.-A., Gaus, K., Quinn, C. M., Wright, J., Sloane, T., Sviridov, D., Fu, Y., Sullivan, D., Burnett, J. R., et al. (2004) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 47

Effect of Carboxyl-Terminal Truncation on Structure and Lipid Interaction of Human Apolipoprotein E4

Tanaka, M., Vedhachalam, C., Sakamoto, T., Dhanasekaran, P., Phillips, M. C., Lund-Katz, S., & Saito, H. (2006) · Biochemistry

Alzheimer's disease research and treatmentsProtein Structure and Dynamics

Cited by 43

Effects of polymorphism on the microenvironment of the LDL receptor-binding region of human apoE

Lund-Katz, S., Wehrli, S., Zaiou, M., Newhouse, Y., Weisgraber, K. H., & Phillips, M. C. (2001) · Journal of Lipid Research

Alzheimer's disease research and treatmentsLipoproteins and Cardiovascular Health

Cited by 40

Structural Analysis of Lipoprotein E Particles

Schneeweis, L. A., Koppaka, V., Lund-Katz, S., Phillips, M. C., & Axelsen, P. H. (2005) · Biochemistry

Cholesterol and Lipid MetabolismLipid Membrane Structure and Behavior

Cited by 39