Bologa, Cristian G.

A comprehensive map of molecular drug targets

Santos, R., Ursu, O., Gaulton, A., Bento, A. P., Donadi, R. S., Bologa, C. G., Karlsson, A., Al-Lazikani, B., Hersey, A., Oprea, T. I., et al. (2017) · Nature Reviews Drug Discovery

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 2,427

How many rare diseases are there?

Haendel, M., Vasilevsky, N., Unni, D., Bologa, C., Harris, N., Rehm, H., Hamosh, A., Baynam, G., Groza, T., McMurry, J., et al. (2020) · Nature Reviews Drug Discovery

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 554

Unexplored therapeutic opportunities in the human genome

Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., et al. (2018) · Nature Reviews Drug Discovery

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 378

DrugCentral: online drug compendium

Ursu, O., Holmes, J., Knockel, J., Bologa, C. G., Yang, J. J., Mathias, S. L., Nelson, S. J., & Oprea, T. I. (2017) · Nucleic Acids Research

Computational Drug Discovery MethodsBiomedical Text Mining and Ontologies

Cited by 323

Pharos: collating protein information to shed light on the druggable genome

Nguyen, D.-T., Mathias, S., Bologa, C., Brunak, S., Fernandez, N., Gaulton, A., Hersey, A., Holmes, J., Jensen, L. J., Karlsson, A., et al. (2017) · Nucleic Acids Research

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 279

DrugCentral 2021 supports drug discovery and repositioning

Avram, S., Bologa, C. G., Holmes, J., Bocci, G., Wilson, T. B., Nguyen, D.-T., Curpan, R., Halip, L., Bora, A., Yang, J. J., et al. (2021) · Nucleic Acids Research

Computational Drug Discovery MethodsPharmacovigilance and Adverse Drug Reactions

Cited by 189

TCRD and pharos 2021: mining the human proteome for disease biology

Sheils, T. K., Mathias, S. L., Kelleher, K. J., Siramshetty, V. B., Nguyen, D.-T., Bologa, C. G., Jensen, L. J., Vidović, D., Koleti, A., Schürer, S. C., et al. (2021) · Nucleic Acids Research

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 160

Pharos 2023: an integrated resource for the understudied human proteome

Kelleher, K. J., Sheils, T. K., Mathias, S. L., Yang, J. J., Metzger, V. T., Siramshetty, V. B., Nguyen, D.-T., Jensen, L. J., Vidović, D., Schürer, S. C., et al. (2023) · Nucleic Acids Research

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 137

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public–private partnership benchmarking initiative to enable the development of computational methods for hit-finding

Ackloo, S., Al-awar, R., Amaro, R. E., Arrowsmith, C. H., Azevedo, H., Batey, R. A., Bengio, Y., Betz, U. A. K., Bologa, C. G., Chodera, J. D., et al. (2022) · Nature Reviews Chemistry

Computational Drug Discovery MethodsProtein Degradation and Inhibitors

Cited by 112

Badapple: promiscuity patterns from noisy evidence

Yang, J. J., Ursu, O., Lipinski, C. A., Sklar, L. A., Oprea, T. I., & Bologa, C. G. (2016) · Journal of Cheminformatics

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 103

DrugCentral 2023 extends human clinical data and integrates veterinary drugs

Avram, S., Wilson, T. B., Curpan, R., Halip, L., Borota, A., Bora, A., Bologa, C. G., Holmes, J., Knockel, J., Yang, J. J., et al. (2023) · Nucleic Acids Research

Computational Drug Discovery MethodsPharmacovigilance and Adverse Drug Reactions

Cited by 101

An automated PLS search for biologically relevant QSAR descriptors

Olah, M., Bologa, C., & Oprea, T. I. (2004) · Journal of Computer-Aided Molecular Design

Computational Drug Discovery MethodsMachine Learning in Materials Science

Cited by 91

Machine learning prediction and tau-based screening identifies potential Alzheimer’s disease genes relevant to immunity

Binder, J., Ursu, O., Bologa, C., Jiang, S., Maphis, N., Dadras, S., Chisholm, D., Weick, J., Myers, O., Kumar, P., et al. (2022) · Communications Biology

Alzheimer's disease research and treatmentsBioinformatics and Genomic Networks

Cited by 49

TIN-X: target importance and novelty explorer

Cannon, D. C., Yang, J. J., Mathias, S. L., Ursu, O., Mani, S., Waller, A., Schürer, S. C., Jensen, L. J., Sklar, L. A., Bologa, C. G., et al. (2017) · Bioinformatics

Biomedical Text Mining and OntologiesBioinformatics and Genomic Networks

Cited by 34

Removal of non benzidine direct red dye from aqueous solution by using natural sorbents: beech and silver fir

Muntean, S. G., Todea, A., Bakardjieva, S., & Bologa, C. (2017) · DESALINATION AND WATER TREATMENT

Adsorption and biosorption for pollutant removalCoagulation and Flocculation Studies

Cited by 24

Post-High-Throughput Screening Analysis: An Empirical Compound Prioritization Scheme

Oprea, T. I., Bologa, C. G., Edwards, B. S., Prossnitz, E. R., & Sklar, L. A. (2005) · SLAS Discovery

Computational Drug Discovery MethodsAnimal testing and alternatives

Cited by 24

Formalizing drug indications on the road to therapeutic intent

Nelson, S. J., Oprea, T. I., Ursu, O., Bologa, C. G., Zaveri, A., Holmes, J., Yang, J. J., Mathias, S. L., Mani, S., Tuttle, M. S., et al. (2017) · Journal of the American Medical Informatics Association

Biomedical Text Mining and OntologiesSemantic Web and Ontologies

Cited by 9