Sweatt, J. David

Lasting epigenetic influence of early-life adversity on the BDNF gene

Roth, T. L., Lubin, F. D., Funk, A. J., & Sweatt, J. D. (2009) · Biological Psychiatry

Child Abuse and TraumaEpigenetics and DNA Methylation

Cited by 1,273

The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory

Sweatt, J. D. (2001) · Journal of Neurochemistry

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 1,131

Regulation of histone acetylation during memory formation in the hippocampus

Levenson, J. M., O'Riordan, K. J., Brown, K. D., Trinh, M. A., Molfese, D. L., & Sweatt, J. D. (2004) · Journal of Biological Chemistry

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 1,131

The MAPK cascade is required for mammalian associative learning

Atkins, C. M., Selcher, J. C., Petraitis, J. J., Trzaskos, J. M., & Sweatt, J. D. (1998) · Nature Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 1,083

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

Feng, J., Zhou, Y., Campbell, S. L., Le, T., Li, E., Sweatt, J. D., Silva, A. J., & Fan, G. (2010) · Nature Neuroscience

Epigenetics and DNA MethylationMemory and Neural Mechanisms

Cited by 1,019

Mutation of the Angelman Ubiquitin Ligase in Mice Causes Increased Cytoplasmic p53 and Deficits of Contextual Learning and Long-Term Potentiation

Jiang, Y.-H., Armstrong, D., Albrecht, U., Atkins, C. M., Noebels, J. L., Eichele, G., Sweatt, J. D., & Beaudet, A. L. (1998) · Neuron

Genetic Syndromes and ImprintingGenetics and Neurodevelopmental Disorders

Cited by 852

Epigenetic Regulation of bdnf Gene Transcription in the Consolidation of Fear Memory

Lubin, F. D., Roth, T. L., & Sweatt, J. D. (2008) · The Journal of Neuroscience

Memory and Neural MechanismsEpigenetics and DNA Methylation

Cited by 793

Epigenetic mechanisms in memory formation

Levenson, J. M., & Sweatt, J. D. (2005) · Nature Reviews Neuroscience

Memory and Neural MechanismsEpigenetics and DNA Methylation

Cited by 767

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

Kilgore, M., Miller, C. A., Fass, D. M., Hennig, K. M., Haggarty, S. J., Sweatt, J. D., & Rumbaugh, G. (2010) · Neuropsychopharmacology

Alzheimer's disease research and treatmentsHistone Deacetylase Inhibitors Research

Cited by 727

Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning

Weeber, E. J., Beffert, U., Jones, C., Christian, J. M., Förster, E., Sweatt, J. D., & Herz, J. (2002) · Journal of Biological Chemistry

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 623

Learning and Memory and Synaptic Plasticity Are Impaired in a Mouse Model of Rett Syndrome

Moretti, P., Levenson, J. M., Battaglia, F., Atkinson, R., Teague, R., Antalffy, B., Armstrong, D., Arancio, O., Sweatt, J. D., & Zoghbi, H. Y. (2006) · The Journal of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 545

Epigenetic mechanisms in cognition

Day, J. J., & Sweatt, J. D. (2011) · Neuron

Memory and Neural MechanismsEpigenetics and DNA Methylation

Cited by 510

Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2

Beffert, U., Weeber, E. J., Durudas, A., Qiu, S., Masiulis, I., Sweatt, J. D., Li, W.-P., Adelmann, G., Frotscher, M., Hammer, R. E., et al. (2005) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 497

β-Amyloid Activates the Mitogen-Activated Protein Kinase Cascade via Hippocampal α7 Nicotinic Acetylcholine Receptors:In Vitro and In Vivo Mechanisms Related to Alzheimer's Disease

Dineley, K. T., Westerman, M., Bui, D., Bell, K., Ashe, K. H., & Sweatt, J. D. (2001) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNicotinic Acetylcholine Receptors Study

Cited by 462

A Long CAG Repeat in the Mouse Sca1 Locus Replicates SCA1 Features and Reveals the Impact of Protein Solubility on Selective Neurodegeneration

Watase, K., Weeber, E. J., Xu, B., Antalffy, B., Yuva-Paylor, L., Hashimoto, K., Kano, M., Atkinson, R., Sun, Y., Armstrong, D. L., et al. (2002) · Neuron

Genetic Neurodegenerative DiseasesAmyotrophic Lateral Sclerosis Research

Cited by 359

ERK/MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning

Chwang, W. B., O’Riordan, K. J., Levenson, J. M., & Sweatt, J. D. (2006) · Learning & Memory

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 341

A Necessity for MAP Kinase Activation in Mammalian Spatial Learning

Selcher, J. C., Atkins, C. M., Trzaskos, J. M., Paylor, R., & Sweatt, J. D. (1999) · Learning & Memory

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 341

The Emerging Field of Neuroepigenetics

Sweatt, J. D. (2013) · Neuron

Epigenetics and DNA MethylationMemory and Neural Mechanisms

Cited by 324

Protein kinase C overactivity impairs prefrontal cortical regulation of working memory

Birnbaum, S. G., Yuan, P. X., Wang, M., Vijayraghavan, S., Bloom, A. K., Davis, D. J., Gobeske, K. T., Sweatt, J. D., Manji, H. K., & Arnsten, A. F. T. (2004) · Science

Neural and Behavioral Psychology StudiesNeuroscience and Neuropharmacology Research

Cited by 318

N-methyl-D-aspartate receptor activation increases cAMP levels and voltage-gated Ca2+ channel activity in area CA1 of hippocampus.

Chetkovich, D. M., Gray, R., Johnston, D., & Sweatt, J. D. (1991) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchIon channel regulation and function

Cited by 284

Deletion of ERK2 Mitogen-Activated Protein Kinase Identifies Its Key Roles in Cortical Neurogenesis and Cognitive Function

Samuels, I. S., Karlo, J. C., Faruzzi, A. N., Pickering, K., Herrup, K., Sweatt, J. D., Saitta, S. C., & Landreth, G. E. (2008) · Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsGenetics and Neurodevelopmental Disorders

Cited by 278

Neuronal LRP1 Functionally Associates with Postsynaptic Proteins and Is Required for Normal Motor Function in Mice

May, P., Rohlmann, A., Bock, H. H., Zurhove, K., Marth, J. D., Schomburg, E. D., Noebels, J. L., Beffert, U., Sweatt, J. D., Weeber, E. J., et al. (2004) · Molecular and Cellular Biology

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 236

Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances

Polter, A., Beurel, E., Yang, S., Garner, R., Song, L., Miller, C. A., Sweatt, J. D., McMahon, L., Bartolucci, A. A., Li, X., et al. (2010) · Neuropsychopharmacology

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 225

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

Lee, S. E., Simons, S. B., Heldt, S. A., Zhao, M., Schroeder, J. P., Vellano, C. P., Cowan, D. P., Ramineni, S., Yates, C. K., Feng, Y., et al. (2010) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 224