Terwel, Dick

Aggregated Tau activates NLRP3–ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo

Stancu, I.-C., Cremers, N., Vanrusselt, H., Couturier, J., Vanoosthuyse, A., Kessels, S., Lodder, C., Brône, B., Huaux, F., Octave, J.-N., et al. (2019) · Acta Neuropathologica

Alzheimer's disease research and treatmentsInflammasome and immune disorders

Cited by 447

Neuroinflammatory processes in Alzheimer’s disease

Heneka, M. T., O’Banion, M. K., Terwel, D., & Kummer, M. P. (2010) · Journal of Neural Transmission

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 433

Nitration of Tyrosine 10 Critically Enhances Amyloid β Aggregation and Plaque Formation

Kummer, M. P., Hermes, M., Delekarte, A., Hammerschmidt, T., Kumar, S., Terwel, D., Walter, J., Pape, H.-C., König, S., Roeber, S., et al. (2011) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 336

Amyloid Activates GSK-3β to Aggravate Neuronal Tauopathy in Bigenic Mice

Terwel, D., Muyllaert, D., Dewachter, I., Borghgraef, P., Croes, S., Devijver, H., & Van Leuven, F. (2008) · The American Journal of Pathology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 300

Models of β-amyloid induced Tau-pathology: The long and “folded” road to understand the mechanism

Stancu, I.-C., Vasconcelos, B., Terwel, D., & Dewachter, I. (2014) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 256

Critical Role of Astroglial Apolipoprotein E and Liver X Receptor-α Expression for Microglial Aβ Phagocytosis

Terwel, D., Steffensen, K. R., Verghese, P. B., Kummer, M. P., Gustafsson, J.-Å., Holtzman, D. M., & Heneka, M. T. (2011) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 190

Axonal transport, tau protein, and neurodegeneration in Alzheimer's disease

Terwel, D., Dewachter, I., & Van Leuven, F. (2002) · NeuroMolecular Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 146

Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice

Stancu, I.-C., Vasconcelos, B., Ris, L., Wang, P., Villers, A., Peeraer, E., Buist, A., Terwel, D., Baatsen, P., Oyelami, T., et al. (2015) · Acta Neuropathologica

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 143

Apolipoprotein E Protects against Neuropathology Induced by a High-Fat Diet and Maintains the Integrity of the Blood-Brain Barrier during Aging

Mulder, M., Blokland, A., van den Berg, D.-J., Schulten, H., Bakker, A. H. F., Terwel, D., Honig, W., de Kloet, E. R., Havekes, L. M., Steinbusch, H. W. M., et al. (2001) · Laboratory Investigation

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 74

The NLRP3 inflammasome modulates tau pathology and neurodegeneration in a tauopathy model

Stancu, I. C., Lodder, C., Botella Lucena, P., Vanherle, S., Gutiérrez de Ravé, M., Terwel, D., Bottelbergs, A., & Dewachter, I. (2022) · Glia

Alzheimer's disease research and treatmentsInflammasome and immune disorders

Cited by 72

PPARγ and RXRγ ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models

Papi, A., Tatenhorst, L., Terwel, D., Hermes, M., Kummer, M. P., Orlandi, M., & Heneka, M. T. (2009) · Journal of Neurochemistry

Glioma Diagnosis and TreatmentPeroxisome Proliferator-Activated Receptors

Cited by 55

Possible Link between Lipid Metabolism and Cerebral Amyloid Angiopathy in Alzheimer’s Disease: A Role for High-Density Lipoproteins?

Mulder, M., & Terwel, D. (1998) · Pathophysiology of Haemostasis and Thrombosis

Alzheimer's disease research and treatmentsCholesterol and Lipid Metabolism

Cited by 40