Parker, Joel S.

Cells exhibiting strong p16 INK4a promoter activation in vivo display features of senescence

Liu, J.-Y., Souroullas, G. P., Diekman, B. O., Krishnamurthy, J., Hall, B. M., Sorrentino, J. A., Parker, J. S., Sessions, G. A., Gudkov, A. V., & Sharpless, N. E. (2019) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

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Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma

Smith, C. C., Beckermann, K. E., Bortone, D. S., De Cubas, A. A., Bixby, L. M., Lee, S. J., Panda, A., Ganesan, S., Bhanot, G., Wallen, E. M., et al. (2018) · Journal of Clinical Investigation

Cancer Immunotherapy and BiomarkersRenal cell carcinoma treatment

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An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation

Souroullas, G. P., Jeck, W. R., Parker, J. S., Simon, J. M., Liu, J.-Y., Paulk, J., Xiong, J., Clark, K. S., Fedoriw, Y., Qi, J., et al. (2016) · Nature Medicine

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

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Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex

Zawistowski, J. S., Bevill, S. M., Goulet, D. R., Stuhlmiller, T. J., Beltran, A. S., Olivares-Quintero, J. F., Singh, D., Sciaky, N., Parker, J. S., Rashid, N. U., et al. (2017) · Cancer Discovery

Melanoma and MAPK PathwaysChromatin Remodeling and Cancer

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Comprehensive pan-genomic characterization of adrenocortical carcinoma

Zheng, S., Cherniack, A. D., Dewal, N., Moffitt, R. A., Danilova, L., Murray, B. A., Lerario, A. M., Else, T., Knijnenburg, T. A., Ciriello, G., et al. (2016) · Cancer Cell

Adrenal and Paraganglionic TumorsChromatin Remodeling and Cancer

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Rapid idiosyncratic mechanisms of clinical resistance to KRAS G12C inhibition

Tsai, Y. S., Woodcock, M. G., Azam, S. H., Thorne, L. B., Kanchi, K. L., Parker, J. S., Vincent, B. G., & Pecot, C. V. (2022) · Journal of Clinical Investigation

Lung Cancer Treatments and MutationsProtein Kinase Regulation and GTPase Signaling

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Histone deacetylase 11 inhibition promotes breast cancer metastasis from lymph nodes

Leslie, P. L., Chao, Y. L., Tsai, Y.-H., Ghosh, S. K., Porrello, A., Van Swearingen, A. E. D., Harrison, E. B., Cooley, B. C., Parker, J. S., Carey, L. A., et al. (2019) · Nature Communications

Histone Deacetylase Inhibitors ResearchMechanisms of cancer metastasis

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A Functional riboSNitch in the 3′ Untranslated Region of FKBP5 Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain

Linnstaedt, S. D., Riker, K. D., Rueckeis, C. A., Kutchko, K. M., Lackey, L., McCarthy, K. R., Tsai, Y.-H., Parker, J. S., Kurz, M. C., Hendry, P. L., et al. (2018) · The Journal of Neuroscience

Stress Responses and CortisolPosttraumatic Stress Disorder Research

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