Kappos, Ludwig

Genome-wide Association Study in a High-Risk Isolate for Multiple Sclerosis Reveals Associated Variants in STAT3 Gene

Jakkula, E., Leppä, V., Sulonen, A.-M., Varilo, T., Kallio, S., Kemppinen, A., Purcell, S., Koivisto, K., Tienari, P., Sumelahti, M.-L., et al. (2010) · The American Journal of Human Genetics

Multiple Sclerosis Research StudiesGenetic Associations and Epidemiology

Cited by 245

Ponesimod Compared With Teriflunomide in Patients With Relapsing Multiple Sclerosis in the Active-Comparator Phase 3 OPTIMUM Study: A Randomized Clinical Trial

Kappos, L., Fox, R. J., Burcklen, M., Freedman, M. S., Havrdová, E. K., Hennessy, B., Hohlfeld, R., Lublin, F., Montalban, X., Pozzilli, C., et al. (2021) · JAMA Neurology

Multiple Sclerosis Research StudiesSphingolipid Metabolism and Signaling

Cited by 228

Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice.

Ozcelik, S., Fraser, G., Castets, P., Schaeffer, V., Skachokova, Z., Breu, K., Clavaguera, F., Sinnreich, M., Kappos, L., Goedert, M., et al. (2013) · PLoS ONE

Alzheimer's disease research and treatmentsAutophagy in Disease and Therapy

Cited by 226

Slowly expanding/evolving lesions as a magnetic resonance imaging marker of chronic active multiple sclerosis lesions

Elliott, C., Wolinsky, J. S., Hauser, S. L., Kappos, L., Barkhof, F., Bernasconi, C., Wei, W., Belachew, S., & Arnold, D. L. (2019) · Multiple Sclerosis Journal

Multiple Sclerosis Research StudiesAdvanced MRI Techniques and Applications

Cited by 217

Association Between Serum Neurofilament Light Chain Levels and Long-term Disease Course Among Patients With Multiple Sclerosis Followed up for 12 Years

Cantó, E., Barro, C., Zhao, C., Caillier, S. J., Michalak, Z., Bove, R., Tomic, D., Santaniello, A., Häring, D. A., Hollenbach, J., et al. (2019) · JAMA Neurology

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 199

Health‐related quality of life in multiple sclerosis: effects of natalizumab

Rudick, R. A., Miller, D., Hass, S., Hutchinson, M., Calabresi, P. A., Confavreux, C., Galetta, S. L., Giovannoni, G., Havrdova, E., Kappos, L., et al. (2007) · Annals of Neurology

Multiple Sclerosis Research StudiesHealth Systems, Economic Evaluations, Quality of Life

Cited by 195

Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes

Cantó, E., Tintoré, M., Villar, L. M., Costa, C., Nurtdinov, R., Álvarez-Cermeño, J. C., Arrambide, G., Reverter, F., Deisenhammer, F., Hegen, H., et al. (2015) · Brain

Multiple Sclerosis Research StudiesPeripheral Neuropathies and Disorders

Cited by 193

A comparative study of CSF neurofilament light and heavy chain protein in MS

Kuhle, J., Plattner, K., Bestwick, J. P., Lindberg, R. L., Ramagopalan, S. V., Norgren, N., Nissim, A., Malaspina, A., Leppert, D., Giovannoni, G., et al. (2013) · Multiple Sclerosis Journal

Multiple Sclerosis Research StudiesPeripheral Neuropathies and Disorders

Cited by 155

Long-term follow-up from the ORATORIO trial of ocrelizumab for primary progressive multiple sclerosis: a post-hoc analysis from the ongoing open-label extension of the randomised, placebo-controlled, phase 3 trial

Wolinsky, J. S., Arnold, D. L., Brochet, B., Hartung, H.-P., Montalban, X., Naismith, R. T., Manfrini, M., Overell, J., Koendgen, H., Sauter, A., et al. (2020) · The Lancet Neurology

Multiple Sclerosis Research StudiesChronic Lymphocytic Leukemia Research

Cited by 150

2024 MAGNIMS–CMSC–NAIMS consensus recommendations on the use of MRI for the diagnosis of multiple sclerosis

Barkhof, F., Reich, D. S., Oh, J., Rocca, M. A., Li, D. K. B., Sati, P., Azevedo, C. J., Bagnato, F., Calabresi, P. A., Ciccarelli, O., et al. (2025) · The Lancet Neurology

Multiple Sclerosis Research StudiesAdvanced MRI Techniques and Applications

Cited by 113

The Swiss Multiple Sclerosis Cohort-Study (SMSC): A Prospective Swiss Wide Investigation of Key Phases in Disease Evolution and New Treatment Options

Disanto, G., Benkert, P., Lorscheider, J., Mueller, S., Vehoff, J., Zecca, C., Ramseier, S., Achtnichts, L., Findling, O., Nedeltchev, K., et al. (2016) · PLOS ONE

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 76

Multiple sclerosis relapses are associated with increased fatigue and reduced health-related quality of life—A post hoc analysis of the TEMSO and TOWER studies

Mäurer, M., Comi, G., Freedman, M. S., Kappos, L., Olsson, T. P., Wolinsky, J. S., Miller, A. E., Dive-Pouletty, C., Bozzi, S., & O’Connor, P. W. (2016) · Multiple Sclerosis and Related Disorders

Multiple Sclerosis Research StudiesHealth Systems, Economic Evaluations, Quality of Life

Cited by 39

Body mass index as a predictor of MS activity and progression among participants in BENEFIT

Manuel Escobar, J., Cortese, M., Edan, G., Freedman, M. S., Hartung, H.-P., Montalbán, X., Sandbrink, R., Radü, E.-W., Barkhof, F., Wicklein, E.-M., et al. (2022) · Multiple Sclerosis Journal

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 38

Time is myelin: Early cortical myelin repair prevents atrophy and clinical progression in multiple sclerosis

Lazzarotto, A., Hamzaoui, M., Tonietto, M., Dubessy, A.-L., Khalil, M., Pirpamer, L., Ropele, S., Enzinger, C., Battaglini, M., Stromillo, M. L., et al. (2024) · Brain

Multiple Sclerosis Research StudiesAdvanced Neuroimaging Techniques and Applications

Cited by 33

Changes in the Cerebrospinal Fluid and Plasma Lipidome in Patients with Rett Syndrome

Zandl-Lang, M., Züllig, T., Trötzmüller, M., Naegelin, Y., Abela, L., Wilken, B., Scholl-Buergi, S., Karall, D., Kappos, L., Köfeler, H., et al. (2022) · Metabolites

Genetics and Neurodevelopmental DisordersMetabolomics and Mass Spectrometry Studies

Cited by 30

Death Anxiety and Attitudes towards Death in Patients with Multiple Sclerosis: An Exploratory Study

Francalancia, J., Mavrogiorgou, P., Juckel, G., Mitrovic, T., Kuhle, J., Naegelin, Y., Kappos, L., & Calabrese, P. (2021) · Brain Sciences

Multiple Sclerosis Research StudiesDeath Anxiety and Social Exclusion

Cited by 19