Auchus, Richard J.

Cofactors, redox state, and directional preferences of hydroxysteroid dehydrogenases

Sherbet, D. P., Papari-Zareei, M., Khan, N., Sharma, K. K., Brandmaier, A., Rambally, S., Chattopadhyay, A., Andersson, S., Agarwal, A. K., & Auchus, R. J. (2007) · Molecular and Cellular Endocrinology

Steroid Chemistry and BiochemistryAldose Reductase and Taurine

Cited by 33

Androgen excess and diagnostic steroid biomarkers for nonclassic 21-hydroxylase deficiency without cosyntropin stimulation

Turcu, A. F., El-Maouche, D., Zhao, L., Nanba, A. T., Gaynor, A., Veeraraghavan, P., Auchus, R. J., & Merke, D. P. (2020) · European Journal of Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 33

Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype

McCammon, K. M., Panda, S. P., Xia, C., Kim, J.-J. P., Moutinho, D., Kranendonk, M., Auchus, R. J., Lafer, E. M., Ghosh, D., Martasek, P., et al. (2016) · Journal of Biological Chemistry

Pharmacogenetics and Drug MetabolismProtein Structure and Dynamics

Cited by 33

Role of the Alternate Pathway of Dihydrotestosterone Formation in Virilization of the Wolffian Ducts of the Tammar Wallaby,Macropus eugenii

Shaw, G., Fenelon, J., Sichlau, M., Auchus, R. J., Wilson, J. D., & Renfree, M. B. (2006) · Endocrinology

Sexual Differentiation and DisordersSperm and Testicular Function

Cited by 32

Adrenocorticotropin Acutely Regulates Pregnenolone Sulfate Production by the Human Adrenal In Vivo and In Vitro

Rege, J., Nanba, A. T., Auchus, R. J., Ren, J., Peng, H.-M., Rainey, W. E., & Turcu, A. F. (2018) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersHormonal Regulation and Hypertension

Cited by 30

Why human cytochrome P450c21 is a progesterone 21-hydroxylase

Mizrachi, D., Wang, Z., Sharma, K. K., Gupta, M. K., Xu, K., Dwyer, C. R., & Auchus, R. J. (2011) · Biochemistry

Metal-Catalyzed Oxygenation MechanismsProtein Structure and Dynamics

Cited by 28

Clamping Cortisol and Testosterone Mitigates the Development of Insulin Resistance during Sleep Restriction in Men

Liu, P. Y., Lawrence-Sidebottom, D., Piotrowska, K., Zhang, W., Iranmanesh, A., Auchus, R. J., Veldhuis, J. D., & Van Dongen, H. P. A. (2021) · The Journal of Clinical Endocrinology & Metabolism

Sleep and Work-Related FatigueCircadian rhythm and melatonin

Cited by 28

Arginine 276 controls the directional preference of AKR1C9 (rat liver 3α-hydroxysteroid dehydrogenase) in human embryonic kidney 293 cells

Papari-Zareei, M., Brandmaier, A., & Auchus, R. J. (2006) · Endocrinology

Aldose Reductase and TaurineSteroid Chemistry and Biochemistry

Cited by 23

Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17β-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells

Sherbet, D. P., Guryev, O. L., Papari-Zareei, M., Mizrachi, D., Rambally, S., Akbar, S., & Auchus, R. J. (2009) · Endocrinology

Estrogen and related hormone effectsSteroid Chemistry and Biochemistry

Cited by 22

24-Hour Profiles of 11-Oxygenated C19 Steroids and Δ5-Steroid Sulfates during Oral and Continuous Subcutaneous Glucocorticoids in 21-Hydroxylase Deficiency

Turcu, A. F., Mallappa, A., Nella, A. A., Chen, X., Zhao, L., Nanba, A. T., Byrd, J. B., Auchus, R. J., & Merke, D. P. (2021) · Frontiers in Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 20

Circadian Rhythms of 11-Oxygenated C19 Steroids and 5-Steroid Sulfates in Healthy Men

Turcu, A. F., Zhao, L., Chen, X., Yang, R., Rege, J., Rainey, W. E., Veldhuis, J. D., & Auchus, R. J. (2021) · European Journal of Endocrinology

Adrenal Hormones and DisordersHormonal and reproductive studies

Cited by 19

Solid-state NMR observation of cysteine and lysine Michael adducts of inactivated estradiol dehydrogenase

Auchus, R. J., Covey, D. F., Bork, V, & Schaefer, J. (1988) · Journal of Biological Chemistry

Advanced NMR Techniques and ApplicationsSteroid Chemistry and Biochemistry

Cited by 18

Non-traditional metabolic pathways of adrenal steroids

Auchus, R. J. (2009) · Reviews in Endocrine and Metabolic Disorders

Adrenal Hormones and DisordersSteroid Chemistry and Biochemistry

Cited by 17

Catalytic modulation of human cytochromes P450 17A1 and P450 11B2 by phospholipid

Peng, H.-M., Barlow, C., & Auchus, R. J. (2018) · The Journal of Steroid Biochemistry and Molecular Biology

Steroid Chemistry and BiochemistryLipid Membrane Structure and Behavior

Cited by 14

A randomized, placebo-controlled proof-of-concept, crossover trial of phenytoin for hydrocortisone-induced declarative memory changes

Brown, E. S., Lu, H., Denniston, D., Uh, J., Thomas, B. P., Carmody, T. J., Auchus, R. J., Diaz-Arrastia, R., & Tamminga, C. (2013) · Journal of Affective Disorders

Stress Responses and CortisolMemory and Neural Mechanisms

Cited by 11

Distinctive profile of the 17-hydroxylase and 17,20-lyase activities revealed by urinary steroid metabolomes of patients with CYP17 deficiency

Neres, M. S., Auchus, R. J., Shackleton, C. H. L., & Kater, C. E. (2010) · Arquivos Brasileiros de Endocrinologia & Metabologia

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 10

Ontogeny and pathway of formation of 5a-androstane-3a,17ß-diol in the testes of the immature brushtail possum Trichosurus vulpecula

Wilson, J. D., Shaw, G., Renfree, M. B., Auchus, R. J., Leihy, M. W., & Eckery, D. C. (2005) · Reproduction Fertility and Development

Sperm and Testicular FunctionSexual Differentiation and Disorders

Cited by 10

Editorial: The New Instructions to Authors for the Reporting of Steroid Hormone Measurements

Wierman, M. E., Auchus, R. J., Haisenleder, D. J., Hall, J. E., Handelsman, D., Hankinson, S., Rosner, W., Singh, R. J., Sluss, P. M., & Stanczyk, F. Z. (2014) · Molecular Endocrinology

Academic Writing and PublishingClinical Laboratory Practices and Quality Control

Cited by 9

Formation of 5a-reduced androgens in the testes and urogenital tract of the grey short-tailed opossum, Monodelphis domestica

Wilson, J. D., Renfree, M. B., Auchus, R. J., Pask, A. J., & Shaw, G. (2009) · Reproduction Fertility and Development

Sexual Differentiation and DisordersSperm and Testicular Function

Cited by 8

Design of a Phase 1/2 Open-Label, Dose-Escalation Study of the Safety and Efficacy of Gene Therapy in Adults With Classic Congenital Adrenal Hyperplasia (CAH) Due to 21-hydroxylase Deficiency Through Administration of an Adeno-Associated Virus (AAV) Serotype 5-Based Recombinant Vector Encoding the Human CYP21A2 Gene

Merke, D. P., Auchus, R. J., Sarafoglou, K., Geffner, M. E., Kim, M. S., Escandon, R. D., Bharucha, K. N., Shaywitz, A. J., Eclov, R., Beard, C. W., et al. (2021) · Journal of the Endocrine Society

Virus-based gene therapy researchAdrenal Hormones and Disorders

Cited by 7