Auchus, Richard J.

Steroid 5α-reductase 1 promotes 5α-androstane-3α,17β-diol synthesis in immature mouse testes by two pathways

Mahendroo, M., Wilson, J. D., Richardson, J. A., & Auchus, R. J. (2004) · Molecular and Cellular Endocrinology

Sperm and Testicular FunctionSexual Differentiation and Disorders

Cited by 75

Medroxyprogesterone Acetate and Dexamethasone Are Competitive Inhibitors of Different Human Steroidogenic Enzymes1

Lee, T. C., Miller, W. L., & Auchus, R. J. (1999) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 71

Reversible Sympathetic Overactivity in Hypertensive Patients with Primary Aldosteronism

Kontak, A. C., Wang, Z., Arbique, D., Adams-Huet, B., Auchus, R. J., Nesbitt, S. D., Victor, R. G., & Vongpatanasin, W. (2010) · The Journal of Clinical Endocrinology & Metabolism

Hormonal Regulation and HypertensionBlood Pressure and Hypertension Studies

Cited by 71

Alternative pathway androgen biosynthesis and human fetal female virilization

Reisch, N., Taylor, A. E., Nogueira, E. F., Asby, D. J., Dhir, V., Berry, A., Krone, N., Auchus, R. J., Shackleton, C. H. L., Hanley, N. A., et al. (2019) · Proceedings of the National Academy of Sciences

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 70

Urine Free cortisol in the diagnosis of cushing’s syndrome: Is It worth doing and, If so, how?

Raff, H., Auchus, R. J., Findling, J. W., & Nieman, L. K. (2015) · The Journal of Clinical Endocrinology & Metabolism

Pituitary Gland Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 68

Abiraterone acetate treatment lowers 11-oxygenated androgens

Wright, C., O’Day, P., Alyamani, M., Sharifi, N., & Auchus, R. J. (2020) · European Journal of Endocrinology

Prostate Cancer Treatment and ResearchAdrenal Hormones and Disorders

Cited by 68

Steroid Assays and Endocrinology: Best Practices for Basic Scientists

Auchus, R. J. (2014) · Endocrinology

Clinical Laboratory Practices and Quality ControlAdrenal Hormones and Disorders

Cited by 67

Human Cytochrome b5 Requires Residues E48 and E49 to Stimulate the 17,20-Lyase Activity of Cytochrome P450c17

Naffin-Olivos, J. L., & Auchus, R. J. (2006) · Biochemistry

Metal-Catalyzed Oxygenation MechanismsSteroid Chemistry and Biochemistry

Cited by 66

Management considerations for the adult with congenital adrenal hyperplasia

Auchus, R. J. (2015) · Molecular and Cellular Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 65

Menstrual Cycle Affects Renal-Adrenal and Hemodynamic Responses During Prolonged Standing in the Postural Orthostatic Tachycardia Syndrome

Fu, Q., VanGundy, T. B., Shibata, S., Auchus, R. J., Williams, G. H., & Levine, B. D. (2010) · Hypertension

Cardiovascular Syncope and Autonomic DisordersHeart Rate Variability and Autonomic Control

Cited by 62

Single-dose study of a corticotropin-releasing factor receptor-1 antagonist in women with 21-hydroxylase deficiency

Turcu, A. F., Spencer-Segal, J. L., Farber, R. H., Luo, R., Grigoriadis, D. E., Ramm, C. A., Madrigal, D., Muth, T., O'Brien, C. F., & Auchus, R. J. (2016) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 61

Pitfalls in characterizing P450c17 mutations associated with isolated 17,20 lyase deficiency

Gupta, M. K., Geller, D. H., & Auchus, R. J. (2001) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 59

Deoxycorticosterone inactivation by AKR1C3 in human mineralocorticoid target tissues

Sharma, K. K., Lindqvist, A., Zhou, X. J., Auchus, R. J., Penning, T. M., & Andersson, S. (2006) · Molecular and Cellular Endocrinology

Hormonal Regulation and HypertensionAldose Reductase and Taurine

Cited by 57

Crinecerfont Lowers Elevated Hormone Markers in Adults With 21-Hydroxylase Deficiency Congenital Adrenal Hyperplasia

Auchus, R. J., Sarafoglou, K., Fechner, P. Y., Vogiatzi, M. G., Imel, E. A., Davis, S. M., Giri, N., Sturgeon, J., Roberts, E., Chan, J. L., et al. (2022) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 55

Tildacerfont in Adults With Classic Congenital Adrenal Hyperplasia: Results from Two Phase 2 Studies

Sarafoglou, K., Barnes, C. N., Huang, M., Imel, E. A., Madu, I.-J., Merke, D. P., Moriarty, D., Nakhle, S., Newfield, R. S., Vogiatzi, M. G., et al. (2021) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 46

Cortisol response to operative stress with anesthesia in healthy children

Taylor, L. K., Auchus, R. J., Baskin, L. S., & Miller, W. L. (2013) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 44

Age-dependent increases in adrenal cytochrome b5 and serum 5-androstenediol-3-sulfate

Rege, J., Karashima, S., Lerario, A. M., Smith, J. M., Auchus, R. J., Kasa-Vubu, J. Z., Sasano, H., Nakamura, Y., White, P. C., & Rainey, W. E. (2016) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 40

The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21

Auchus, R. J., Sampath Kumar, A., Andrew Boswell, C., Gupta, M. K., Bruce, K., Rath, N. P., & Covey, D. F. (2003) · Archives of Biochemistry and Biophysics

Steroid Chemistry and BiochemistryMetal-Catalyzed Oxygenation Mechanisms

Cited by 39

11-Oxygenated Androgens Useful in the Setting of Discrepant Conventional Biomarkers in 21-Hydroxylase Deficiency

Jha, S., Turcu, A. F., Sinaii, N., Brookner, B., Auchus, R. J., & Merke, D. P. (2021) · Journal of the Endocrine Society

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 39

Minor activities and transition state properties of the human steroid hydroxylases cytochromes P450c17 and P450c21, from reactions observed with deuterium-labeled substrates

Yoshimoto, F. K., Zhou, Y., Peng, H.-M., Stidd, D., Yoshimoto, J. A., Sharma, K. K., Matthew, S., & Auchus, R. J. (2012) · Biochemistry

Metal-Catalyzed Oxygenation MechanismsPhysical Organic Chemistry and Reaction Kinetics

Cited by 38

Measurement of 18-hydroxycorticosterone during adrenal vein sampling for primary aldosteronism

Auchus, R. J., Chandler, D. W., Singeetham, S., Chokshi, N., Nwariaku, F. E., Dolmatch, B. L., Holt, S. A., Wians, F. H., Josephs, S. C., Trimmer, C. K., et al. (2007) · The Journal of Clinical Endocrinology & Metabolism

Hormonal Regulation and HypertensionAdrenal and Paraganglionic Tumors

Cited by 35

The classic and nonclassic concenital adrenal hyperplasias

Auchus, R. J. (2015) · Endocrine Practice

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 35

A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone

Garrido, M., Peng, H.-M., Yoshimoto, F. K., Upadhyay, S. K., Bratoeff, E., & Auchus, R. J. (2014) · The Journal of Steroid Biochemistry and Molecular Biology

Prostate Cancer Treatment and ResearchSteroid Chemistry and Biochemistry

Cited by 35

A Phase 2, Multicenter Study of Nevanimibe for the Treatment of Congenital Adrenal Hyperplasia

El-Maouche, D., Merke, D. P., Vogiatzi, M. G., Chang, A. Y., Turcu, A. F., Joyal, E. G., Lin, V. H., Weintraub, L., Plaunt, M. R., Mohideen, P., et al. (2020) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 34