Auchus, Richard J.

The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders

Miller, W. L., & Auchus, R. J. (2011) · Endocrine Reviews

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 2,458

Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society* Clinical Practice Guideline

Speiser, P. W., Arlt, W., Auchus, R. J., Baskin, L. S., Conway, G. S., Merke, D. P., Meyer-Bahlburg, H. F. L., Miller, W. L., Murad, M. H., Oberfield, S. E., et al. (2018) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 1,234

Utility, Limitations, and Pitfalls in Measuring Testosterone: An Endocrine Society Position Statement

Rosner, W., Auchus, R. J., Azziz, R., Sluss, P. M., & Raff, H. (2007) · The Journal of Clinical Endocrinology & Metabolism

Hormonal and reproductive studiesClinical Laboratory Practices and Quality Control

Cited by 1,176

Congenital Adrenal Hyperplasia—Current Insights in Pathophysiology, Diagnostics, and Management

Claahsen - van der Grinten, H. L., Speiser, P. W., Ahmed, S. F., Arlt, W., Auchus, R. J., Falhammar, H., Flück, C. E., Guasti, L., Huebner, A., Kortmann, B. B. M., et al. (2022) · Endocrine Reviews

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 556

Cytochrome b 5 Augments the 17,20-Lyase Activity of Human P450c17 without Direct Electron Transfer

Auchus, R. J., Lee, T. C., & Miller, W. L. (1998) · Journal of Biological Chemistry

Steroid Chemistry and BiochemistryMetal-Catalyzed Oxygenation Mechanisms

Cited by 541

Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome

Fleseriu, M., Biller, B. M. K., Findling, J. W., Molitch, M. E., Schteingart, D. E., Gross, C., on behalf of the SEISMIC Study Investigators, The SEISMIC Study Investigators include, Auchus, R., Bailey, T., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism

Pituitary Gland Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 479

An international consortium update: pathophysiology, diagnosis, and treatment of polycystic ovarian syndrome in adolescence

Ibáñez, L., Oberfield, S. E., Witchel, S., Auchus, R. J., Chang, R. J., Codner, E., Dabadghao, P., Darendeliler, F., Elbarbary, N. S., Gambineri, A., et al. (2017) · Hormone Research in Paediatrics

Ovarian function and disordersGenetic and Kidney Cyst Diseases

Cited by 463

The backdoor pathway to dihydrotestosterone

Auchus, R. J. (2004) · Trends in Endocrinology & Metabolism

Hormonal and reproductive studiesSexual Differentiation and Disorders

Cited by 347

Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer

Chang, K.-H., Li, R., Papari-Zareei, M., Watumull, L., Zhao, Y. D., Auchus, R. J., & Sharifi, N. (2011) · Proceedings of the National Academy of Sciences

Prostate Cancer Treatment and ResearchHormonal and reproductive studies

Cited by 346

Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Merke, D. P., & Auchus, R. J. (2020) · New England Journal of Medicine

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 341

The genetic and functional basis of isolated 17,20 lyase deficiency

Geller, D. H., Auchus, R. J., Mendonça, B. B., & Miller, W. L. (1997) · Nature Genetics

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 318

A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer

Chang, K.-H., Li, R., Kuri, B., Lotan, Y., Roehrborn, C. G., Liu, J., Vessella, R., Nelson, P. S., Kapur, P., Guo, X., et al. (2013) · Cell

Prostate Cancer Treatment and ResearchCancer, Lipids, and Metabolism

Cited by 312

Adrenarche—physiology, biochemistry and human disease

Auchus, R. J., & Rainey, W. E. (2004) · Clinical Endocrinology

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 296

THE GENETICS, PATHOPHYSIOLOGX, AND MANAGEMENT OF HUMAN DEFICIENCIES OF P450c17

Auchus, R. J. (2001) · Endocrinology and Metabolism Clinics of North America

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 266

Adrenal-Derived 11-Oxygenated 19-Carbon Steroids are the Dominant Androgens in Classic 21-Hydroxylase Deficiency

Turcu, A. F., Nanba, A. T., Chomic, R., Upadhyay, S. K., Giordano, T. J., Shields, J. J., Merke, D. P., Rainey, W. E., & Auchus, R. J. (2016) · European Journal of Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 231

The regulation of 17,20 lyase activity

Miller, W. L., Auchus, R. J., & Geller, D. H. (1997) · Steroids

Adrenal Hormones and DisordersSexual Differentiation and Disorders

Cited by 227

Two Prevalent CYP17 Mutations and Genotype-Phenotype Correlations in 24 Brazilian Patients with 17-Hydroxylase Deficiency

Costa-Santos, M., Kater, C. E., & Auchus, R. J. (2004) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 224

Efficacy and safety of osilodrostat in patients with Cushing's disease (LINC 3): a multicentre phase III study with a double-blind, randomised withdrawal phase

Pivonello, R., Fleseriu, M., Newell-Price, J., Bertagna, X., Findling, J., Shimatsu, A., Gu, F., Auchus, R., Leelawattana, R., Lee, E. J., et al. (2020) · The Lancet Diabetes & Endocrinology

Pituitary Gland Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 222

11-Oxygenated androgens in health and disease

Turcu, A. F., Rege, J., Auchus, R. J., & Rainey, W. E. (2020) · Nature Reviews Endocrinology

Hormonal and reproductive studiesAdrenal Hormones and Disorders

Cited by 217

Molecular Modeling of Human P450c17 (17α-Hydroxylase/ 17,20-Lyase): Insights into Reaction Mechanisms and Effects of Mutations

Auchus, R. J., & Miller, W. L. (1999) · Molecular Endocrinology

Metal-Catalyzed Oxygenation MechanismsProtein Structure and Dynamics

Cited by 185

P450c17 Mutations R347H and R358Q Selectively Disrupt 17,20-Lyase Activity by Disrupting Interactions with P450 Oxidoreductase and Cytochrome b5

Geller, D. H., Auchus, R. J., & Miller, W. L. (1999) · Molecular Endocrinology

Steroid Chemistry and BiochemistryPharmacogenetics and Drug Metabolism

Cited by 183

Adrenal Steroidogenesis and Congenital Adrenal Hyperplasia

Turcu, A. F., & Auchus, R. J. (2015) · Endocrinology and Metabolism Clinics of North America

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 177

Exercise training versus propranolol in the treatment of the postural orthostatic tachycardia syndrome

Fu, Q., VanGundy, T. B., Shibata, S., Auchus, R. J., Williams, G. H., & Levine, B. D. (2011) · Hypertension

Cardiovascular Syncope and Autonomic DisordersHeart Rate Variability and Autonomic Control

Cited by 175

The 17, 20-Lyase Activity of Cytochrome P450c17 from Human Fetal Testis Favors the Δ5Steroidogenic Pathway

Flück, C. E., Miller, W. L., & Auchus, R. J. (2003) · The Journal of Clinical Endocrinology & Metabolism

Steroid Chemistry and BiochemistrySexual Differentiation and Disorders

Cited by 173