Tang, Daolin

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Stockwell, B. R., Friedmann Angeli, J. P., Bayir, H., Bush, A. I., Conrad, M., Dixon, S. J., Fulda, S., Gascón, S., Hatzios, S. K., Kagan, V. E., et al. (2017) · Cell

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 7,695

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 6,680

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Ferroptosis: process and function

Xie, Y., Hou, W., Song, X., Yu, Y., Huang, J., Sun, X., Kang, R., & Tang, D. (2016) · Cell Death & Differentiation

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 3,727

The Beclin 1 network regulates autophagy and apoptosis

Kang, R., Zeh, H. J., Lotze, M. T., & Tang, D. (2011) · Cell Death & Differentiation

Autophagy in Disease and TherapyCell death mechanisms and regulation

Cited by 2,485

Autophagy promotes ferroptosis by degradation of ferritin

Hou, W., Xie, Y., Song, X., Sun, X., Lotze, M. T., Zeh, H. J., Kang, R., & Tang, D. (2016) · Autophagy

Ferroptosis and cancer prognosisAutophagy in Disease and Therapy

Cited by 2,332

Ferroptosis: machinery and regulation

Chen, X., Li, J., Kang, R., Klionsky, D. J., & Tang, D. (2021) · Autophagy

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 2,099

Activation of the p62–Keap1–NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

Sun, X., Ou, Z., Chen, R., Niu, X., Chen, D., Kang, R., & Tang, D. (2016) · Hepatology

Ferroptosis and cancer prognosisGenomics, phytochemicals, and oxidative stress

Cited by 2,012

Identification of ACSL4 as a biomarker and contributor of ferroptosis

Yuan, H., Li, X., Zhang, X., Kang, R., & Tang, D. (2016) · Biochemical and Biophysical Research Communications

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 1,071

HMGB1 in health and disease

Kang, R., Chen, R., Zhang, Q., Hou, W., Wu, S., Cao, L., Huang, J., Yu, Y., Fan, X.-G., Yan, Z., et al. (2014) · Molecular Aspects of Medicine

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 956

The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity

Xie, Y., Zhu, S., Song, X., Sun, X., Fan, Y., Liu, J., Zhong, M., Yuan, H., Zhang, L., Billiar, T. R., et al. (2017) · Cell Reports

Ferroptosis and cancer prognosisCancer-related Molecular Pathways

Cited by 952

Endogenous HMGB1 regulates autophagy

Tang, D., Kang, R., Livesey, K. M., Cheh, C.-W., Farkas, A., Loughran, P., Hoppe, G., Bianchi, M. E., Tracey, K. J., Zeh, H. J., et al. (2010) · Journal of Cell Biology

Autophagy in Disease and TherapyAdvanced Glycation End Products research

Cited by 951

HSPB1 as a novel regulator of ferroptotic cancer cell death

Sun, X., Ou, Z., Xie, M., Kang, R., Fan, Y., Niu, X., Wang, H., Cao, L., & Tang, D. (2015) · Oncogene

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 666

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein

Dai, E., Han, L., Liu, J., Xie, Y., Kroemer, G., Klionsky, D. J., Zeh, H. J., Kang, R., Wang, J., & Tang, D. (2020) · Autophagy

Immune cells in cancerFerroptosis and cancer prognosis

Cited by 613

HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells

Zhu, S., Zhang, Q., Sun, X., Zeh, H. J., Lotze, M. T., Kang, R., & Tang, D. (2017) · Cancer Research

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 576

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

Tang, D., Kang, R., Cheh, C.-W., Livesey, K. M., Liang, X., Schapiro, N. E., Benschop, R., Sparvero, L. J., Amoscato, A. A., Tracey, K. J., et al. (2010) · Oncogene

Advanced Glycation End Products researchCell death mechanisms and regulation

Cited by 461

Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1

Tang, D., Shi, Y., Kang, R., Li, T., Xiao, W., Wang, H., & Xiao, X. (2007) · Journal of Leukocyte Biology

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 312

The BET family in immunity and disease

Wang, N., Wu, R., Tang, D., & Kang, R. (2021) · Signal Transduction and Targeted Therapy

Protein Degradation and InhibitorsGenomics and Chromatin Dynamics

Cited by 295

NUPR1 is a critical repressor of ferroptosis

Liu, J., Song, X., Kuang, F., Zhang, Q., Xie, Y., Kang, R., Kroemer, G., & Tang, D. (2021) · Nature Communications

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 290

A randomized Phase II preoperative study of autophagy inhibition with high-dose hydroxychloroquine and gemcitabine/nab-paclitaxel in pancreatic cancer patients

Zeh, H. J., Bahary, N., Boone, B. A., Singhi, A. D., Miller-Ocuin, J. L., Normolle, D. P., Zureikat, A. H., Hogg, M. E., Bartlett, D. L., Lee, K. K., et al. (2020) · Clinical Cancer Research

Pancreatic and Hepatic Oncology ResearchAutophagy in Disease and Therapy

Cited by 233

MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells

Kuang, F., Liu, J., Xie, Y., Tang, D., & Kang, R. (2021) · Cell Chemical Biology

Ferroptosis and cancer prognosisGenomics, phytochemicals, and oxidative stress

Cited by 199

The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia

Kang, R., Loux, T., Tang, D., Schapiro, N. E., Vernon, P., Livesey, K. M., Krasinskas, A., Lotze, M. T., & Zeh, H. J. (2012) · Proceedings of the National Academy of Sciences

Advanced Glycation End Products researchPancreatic and Hepatic Oncology Research

Cited by 163

DAMPs, ageing, and cancer: The ‘DAMP Hypothesis’

Huang, J., Xie, Y., Sun, X., Zeh, H. J., Kang, R., Lotze, M. T., & Tang, D. (2015) · Ageing Research Reviews

Advanced Glycation End Products researchImmune Response and Inflammation

Cited by 144