Luster, Andrew D.

Immune cell migration in inflammation: present and future therapeutic targets

Luster, A. D., Alon, R., & von Andrian, U. H. (2005) · Nature Immunology

Chemokine receptors and signalingCell Adhesion Molecules Research

Cited by 1,313

IFN-γ-Inducible Protein 10 (IP-10; CXCL10)-Deficient Mice Reveal a Role for IP-10 in Effector T Cell Generation and Trafficking

Dufour, J. H., Dziejman, M., Liu, M. T., Leung, J. H., Lane, T. E., & Luster, A. D. (2002) · The Journal of Immunology

Chemokine receptors and signalinginterferon and immune responses

Cited by 1,075

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

El Khoury, J., Toft, M., Hickman, S. E., Means, T. K., Terada, K., Geula, C., & Luster, A. D. (2007) · Nature Medicine

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 915

The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak

Tager, A. M., LaCamera, P., Shea, B. S., Campanella, G. S., Selman, M., Zhao, Z., Polosukhin, V., Wain, J., Karimi-Shah, B. A., Kim, N. D., et al. (2008) · Nature Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisSphingolipid Metabolism and Signaling

Cited by 823

Intratumoral activity of the cxcr3 chemokine system is required for the efficacy of anti-PD-1 therapy

Chow, M. T., Ozga, A. J., Servis, R. L., Frederick, D. T., Lo, J. A., Fisher, D. E., Freeman, G. J., Boland, G. M., & Luster, A. D. (2019) · Immunity

Cancer Immunotherapy and BiomarkersChemokine receptors and signaling

Cited by 716

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

Björkbacka, H., Kunjathoor, V. V., Moore, K. J., Koehn, S., Ordija, C. M., Lee, M. A., Means, T., Halmen, K., Luster, A. D., Golenbock, D. T., et al. (2004) · Nature Medicine

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 634

Resistance to Experimental Autoimmune Encephalomyelitis in Mice Lacking the Cc Chemokine Receptor (Ccr2)

Izikson, L., Klein, R. S., Charo, I. F., Weiner, H. L., & Luster, A. D. (2000) · The Journal of Experimental Medicine

Multiple Sclerosis Research StudiesChemokine receptors and signaling

Cited by 584

Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints

Mikucki, M. E., Fisher, D. T., Matsuzaki, J., Skitzki, J. J., Gaulin, N. B., Muhitch, J. B., Ku, A. W., Frelinger, J. G., Odunsi, K., Gajewski, T. F., et al. (2015) · Nature Communications

Chemokine receptors and signalingCancer Immunotherapy and Biomarkers

Cited by 512

Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics

Bromley, S. K., Thomas, S. Y., & Luster, A. D. (2005) · Nature Immunology

Chemokine receptors and signalingT-cell and B-cell Immunology

Cited by 509

CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment

Di Pilato, M., Kfuri-Rubens, R., Pruessmann, J. N., Ozga, A. J., Messemaker, M., Cadilha, B. L., Sivakumar, R., Cianciaruso, C., Warner, R. D., Marangoni, F., et al. (2021) · Cell

Chemokine receptors and signalingCancer Immunotherapy and Biomarkers

Cited by 488

CD36 Mediates the Innate Host Response to β-Amyloid

El Khoury, J. B., Moore, K. J., Means, T. K., Leung, J., Terada, K., Toft, M., Freeman, M. W., & Luster, A. D. (2003) · The Journal of Experimental Medicine

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 483

Neuronal CXCL10 Directs CD8 + T-Cell Recruitment and Control of West Nile Virus Encephalitis

Klein, R. S., Lin, E., Zhang, B., Luster, A. D., Tollett, J., Samuel, M. A., Engle, M., & Diamond, M. S. (2005) · Journal of Virology

Chemokine receptors and signalingMosquito-borne diseases and control

Cited by 424

CD36, a Class B Scavenger Receptor, Is Expressed on Microglia in Alzheimer's Disease Brains and Can Mediate Production of Reactive Oxygen Species in Response to β-Amyloid Fibrils

Coraci, I. S., Husemann, J., Berman, J. W., Hulette, C., Dufour, J. H., Campanella, G. K., Luster, A. D., Silverstein, S. C., & El Khoury, J. B. (2002) · The American Journal of Pathology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 398

Lipid-Cytokine-Chemokine Cascade Drives Neutrophil Recruitment in a Murine Model of Inflammatory Arthritis

Chou, R. C., Kim, N. D., Sadik, C. D., Seung, E., Lan, Y., Byrne, M. H., Haribabu, B., Iwakura, Y., & Luster, A. D. (2010) · Immunity

Chemokine receptors and signalingRheumatoid Arthritis Research and Therapies

Cited by 342

A CD36-initiated Signaling Cascade Mediates Inflammatory Effects of β-Amyloid

Moore, K. J., El Khoury, J., Medeiros, L. A., Terada, K., Geula, C., Luster, A. D., & Freeman, M. W. (2002) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 327

HIV-infected T cells are migratory vehicles for viral dissemination

Murooka, T. T., Deruaz, M., Marangoni, F., Vrbanac, V. D., Seung, E., von Andrian, U. H., Tager, A. M., Luster, A. D., & Mempel, T. R. (2012) · Nature

HIV Research and TreatmentHIV/AIDS Research and Interventions

Cited by 322

Proinflammatory functions of vascular endothelial growth factor in alloimmunity

Reinders, M. E. J., Sho, M., Izawa, A., Wang, P., Mukhopadhyay, D., Koss, K. E., Geehan, C. S., Luster, A. D., Sayegh, M. H., & Briscoe, D. M. (2003) · Journal of Clinical Investigation

Transplantation: Methods and OutcomesAngiogenesis and VEGF in Cancer

Cited by 251

Mechanisms of microglia accumulation in Alzheimer’s disease: therapeutic implications

Khoury, J. E., & Luster, A. D. (2008) · Trends in Pharmacological Sciences

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 171

Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy

Jung, K., Heishi, T., Khan, O. F., Kowalski, P. S., Incio, J., Rahbari, N. N., Chung, E., Clark, J. W., Willett, C. G., Luster, A. D., et al. (2017) · Journal of Clinical Investigation

Immune cells in cancerAngiogenesis and VEGF in Cancer

Cited by 164

Targeting CXCR4-dependent immunosuppressive Ly6C low monocytes improves antiangiogenic therapy in colorectal cancer

Jung, K., Heishi, T., Incio, J., Huang, Y., Beech, E. Y., Pinter, M., Ho, W. W., Kawaguchi, K., Rahbari, N. N., Chung, E., et al. (2017) · Proceedings of the National Academy of Sciences

Angiogenesis and VEGF in CancerChemokine receptors and signaling

Cited by 138

Contribution of CCR4 and CCR8 to antigen-specific TH2 cell trafficking in allergic pulmonary inflammation

Mikhak, Z., Fukui, M., Farsidjani, A., Medoff, B. D., Tager, A. M., & Luster, A. D. (2009) · Journal of Allergy and Clinical Immunology

Asthma and respiratory diseasesChemokine receptors and signaling

Cited by 127

ACKR4 on stromal cells scavenges CCL19 to enable CCR7-dependent trafficking of APCs from inflamed skin to lymph nodes

Bryce, S. A., Wilson, R. A. M., Tiplady, E. M., Asquith, D. L., Bromley, S. K., Luster, A. D., Graham, G. J., & Nibbs, R. J. B. (2016) · The Journal of Immunology

Chemokine receptors and signalingLymphatic System and Diseases

Cited by 71