Tenen, Daniel G.

Zinc finger protein SALL4 functions through an AT-rich motif to regulate gene expression

Kong, N. R., Bassal, M. A., Tan, H. K., Kurland, J. V., Yong, K. J., Young, J. J., Yang, Y., Li, F., Lee, J. D., Liu, Y., et al. (2021) · Cell Reports

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Metabolic alterations mediated by STAT3 promotes drug persistence in CML

Patel, S. B., Nemkov, T., Stefanoni, D., Benavides, G. A., Bassal, M. A., Crown, B. L., Matkins, V. R., Camacho, V., Kuznetsova, V., Hoang, A. T., et al. (2021) · Leukemia

Chronic Myeloid Leukemia TreatmentsAcute Myeloid Leukemia Research

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PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway

Zhou, J., Wu, J., Li, B., Liu, D., Yu, J., Yan, X., Zheng, S., Wang, J., Zhang, L., Zhang, L., et al. (2014) · Leukemia

Acute Myeloid Leukemia ResearchAcute Lymphoblastic Leukemia research

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PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development

Zhao, X., Bartholdy, B., Yamamoto, Y., Evans, E. K., Alberich-Jordà, M., Staber, P. B., Benoukraf, T., Zhang, P., Zhang, J., Trinh, B. Q., et al. (2022) · Communications Biology

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

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Targeting SALL4 by entinostat in lung cancer

Yong, K. J., Li, A., Ou, W.-B., Hong, C. K. Y., Zhao, W., Wang, F., Tatetsu, H., Yan, B., Qi, L., Fletcher, J. A., et al. (2016) · Oncotarget

Histone Deacetylase Inhibitors ResearchLung Cancer Research Studies

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The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells

Staber, P. B., Zhang, P., Ye, M., Welner, R. S., Levantini, E., Di Ruscio, A., Ebralidze, A. K., Bach, C., Zhang, H., Zhang, J., et al. (2014) · Blood

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

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SALL4: An Intriguing Therapeutic Target in Cancer Treatment

Moein, S., Tenen, D. G., Amabile, G., & Chai, L. (2022) · Cells

Protein Degradation and InhibitorsEpigenetics and DNA Methylation

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PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL.

Ueno, S., Tatetsu, H., Hata, H., Iino, T., Niiro, H., Akashi, K., Tenen, D. G., Mitsuya, H., & Okuno, Y. (2009) · Oncogene

Multiple Myeloma Research and TreatmentsCell death mechanisms and regulation

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Targeting transcription factors through an IMiD independent zinc finger domain

Liu, B. H., Liu, M., Radhakrishnan, S., Dai, M.-Y., Jaladanki, C. K., Gao, C., Tang, J. P., Kumari, K., Go, M. L., Vu, K. A. L., et al. (2025) · EMBO Molecular Medicine

Protein Degradation and InhibitorsChromatin Remodeling and Cancer

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Dissecting the cell of origin of aberrant SALL4 expression in myelodysplastic syndrome

Tatetsu, H., Watanabe, M., Liu, J., Tokunaga, K., Iwanaga, E., Komohara, Y., Thrash, E., Bassal, M. A., Matsuoka, M., Tenen, D. G., et al. (2023) · Clinical and Translational Medicine

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

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