Chen, Bifan

Best practices and benchmarks for intact protein analysis for top-down mass spectrometry

Donnelly, D. P., Rawlins, C. M., DeHart, C. J., Fornelli, L., Schachner, L. F., Lin, Z., Lippens, J. L., Aluri, K. C., Sarin, R., Chen, B., et al. (2019) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 377

Top-Down Proteomics: Ready for Prime Time?

Chen, B., Brown, K. A., Lin, Z., & Ge, Y. (2018) · Analytical Chemistry

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 210

Top-Down Proteomics of Large Proteins up to 223 kDa Enabled by Serial Size Exclusion Chromatography Strategy

Cai, W., Tucholski, T., Chen, B., Alpert, A. J., McIlwain, S., Kohmoto, T., Jin, S., & Ge, Y. (2017) · Analytical Chemistry

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 135

A photocleavable surfactant for top-down proteomics

Brown, K. A., Chen, B., Guardado-Alvarez, T. M., Lin, Z., Hwang, L., Ayaz-Guner, S., Jin, S., & Ge, Y. (2019) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 111

Online Hydrophobic Interaction Chromatography–Mass Spectrometry for Top-Down Proteomics

Chen, B., Peng, Y., Valeja, S. G., Xiu, L., Alpert, A. J., & Ge, Y. (2016) · Analytical Chemistry

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 110

Online Hydrophobic Interaction Chromatography–Mass Spectrometry for the Analysis of Intact Monoclonal Antibodies

Chen, B., Lin, Z., Alpert, A. J., Fu, C., Zhang, Q., Pritts, W. A., & Ge, Y. (2018) · Analytical Chemistry

Mass Spectrometry Techniques and ApplicationsProtein purification and stability

Cited by 82

Nanoproteomics enables proteoform-resolved analysis of low-abundance proteins in human serum

Tiambeng, T. N., Roberts, D. S., Brown, K. A., Zhu, Y., Chen, B., Wu, Z., Mitchell, S. D., Guardado-Alvarez, T. M., Jin, S., & Ge, Y. (2020) · Nature Communications

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 76

A Top-Down Proteomics Platform Coupling Serial Size Exclusion Chromatography and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Tucholski, T., Knott, S. J., Chen, B., Pistono, P., Lin, Z., & Ge, Y. (2019) · Analytical Chemistry

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 49

Coupling functionalized cobalt ferrite nanoparticle enrichment with online LC/MS/MS for top-down phosphoproteomics

Chen, B., Hwang, L., Ochowicz, W., Lin, Z., Guardado-Alvarez, T. M., Cai, W., Xiu, L., Dani, K., Colah, C., Jin, S., et al. (2017) · Chemical Science

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 43

Middle-Down Multi-Attribute Analysis of Antibody-Drug Conjugates with Electron Transfer Dissociation

Chen, B., Lin, Z., Zhu, Y., Jin, Y., Larson, E., Xu, Q., Fu, C., Zhang, Z., Zhang, Q., Pritts, W. A., et al. (2019) · Analytical Chemistry

Mass Spectrometry Techniques and ApplicationsBiosimilars and Bioanalytical Methods

Cited by 38

Reproducible large-scale synthesis of surface silanized nanoparticles as an enabling nanoproteomics platform: Enrichment of the human heart phosphoproteome

Roberts, D. S., Chen, B., Tiambeng, T. N., Wu, Z., Ge, Y., & Jin, S. (2019) · Nano Research

Advanced Proteomics Techniques and ApplicationsAdvanced Biosensing Techniques and Applications

Cited by 33

Rapid Analysis of Reduced Antibody Drug Conjugate by Online LC-MS/MS with Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Larson, E. J., Zhu, Y., Wu, Z., Chen, B., Zhang, Z., Zhou, S., Han, L., Zhang, Q., & Ge, Y. (2020) · Analytical Chemistry

Mass Spectrometry Techniques and ApplicationsMonoclonal and Polyclonal Antibodies Research

Cited by 21