George, Olivier

Addiction as a stress surfeit disorder

Koob, G. F., Buck, C. L., Cohen, A., Edwards, S., Park, P. E., Schlosburg, J. E., Schmeichel, B., Vendruscolo, L. F., Wade, C. L., Whitfield, T. W., et al. (2014) · Neuropharmacology

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 483

CRF–CRF 1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats

George, O., Ghozland, S., Azar, M. R., Cottone, P., Zorrilla, E. P., Parsons, L. H., O'Dell, L. E., Richardson, H. N., & Koob, G. F. (2007) · Proceedings of the National Academy of Sciences

Smoking Behavior and CessationNeuropeptides and Animal Physiology

Cited by 245

Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals

Vendruscolo, L. F., Estey, D., Goodell, V., Macshane, L. G., Logrip, M. L., Schlosburg, J. E., McGinn, M. A., Zamora-Martinez, E. R., Belanoff, J. K., Hunt, H. J., et al. (2015) · Journal of Clinical Investigation

Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on Behavior

Cited by 218

Allostasis and addiction: role of the dopamine and corticotropin-releasing factor systems

George, O., Le Moal, M., & Koob, G. F. (2012) · Physiology & Behavior

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 184

Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats

de Guglielmo, G., Kallupi, M., Pomrenze, M. B., Crawford, E., Simpson, S., Schweitzer, P., Koob, G. F., Messing, R. O., & George, O. (2019) · Nature Communications

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 127

Long-term antagonism of κ opioid receptors prevents escalation of and increased motivation for heroin intake

Schlosburg, J. E., Whitfield, T. W., Park, P. E., Crawford, E. F., George, O., Vendruscolo, L. F., & Koob, G. F. (2013) · The Journal of Neuroscience

Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior

Cited by 119

Recruitment of a neuronal ensemble in the central nucleus of the amygdala is required for alcohol dependence

de Guglielmo, G., Crawford, E., Kim, S., Vendruscolo, L. F., Hope, B. T., Brennan, M., Cole, M., Koob, G. F., & George, O. (2016) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 106

Brain-wide functional architecture remodeling by alcohol dependence and abstinence

Kimbrough, A., Lurie, D. J., Collazo, A., Kreifeldt, M., Sidhu, H., Macedo, G. C., D’Esposito, M., Contet, C., & George, O. (2020) · Proceedings of the National Academy of Sciences

Functional Brain Connectivity StudiesSubstance Abuse Treatment and Outcomes

Cited by 97

Control of craving by the prefrontal cortex

George, O., & Koob, G. F. (2013) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 75

κ opioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake

Whitfield, T. W., Schlosburg, J. E., Wee, S., Gould, A., George, O., Grant, Y., Zamora-Martinez, E. R., Edwards, S., Crawford, E., Vendruscolo, L. F., et al. (2015) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 75

Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats

Kallupi, M., Carrette, L. L. G., Kononoff, J., Solberg Woods, L. C., Palmer, A. A., Schweitzer, P., George, O., & de Guglielmo, G. (2020) · Proceedings of the National Academy of Sciences

Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior

Cited by 64

Glucocorticoid receptor modulators decrease alcohol self-administration in male rats

McGinn, M. A., Tunstall, B. J., Schlosburg, J. E., Gregory-Flores, A., George, O., de Guglielmo, G., Mason, B. J., Hunt, H. J., Koob, G. F., & Vendruscolo, L. F. (2021) · Neuropharmacology

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 35

Glucocorticoid receptor-regulated enhancers play a central role in the gene regulatory networks underlying drug addiction

Duttke, S. H., Montilla-Perez, P., Chang, M. W., Li, H., Chen, H., Carrette, L. L. G., Guglielmo, G. D., George, O., Palmer, A. A., Benner, C., et al. (2022) · Frontiers in Neuroscience

Genomics and Chromatin DynamicsNeurotransmitter Receptor Influence on Behavior

Cited by 26

Exposure to passive nicotine vapor in male adolescent rats produces a withdrawal-like state and facilitates nicotine self-administration during adulthood

Kallupi, M., de Guglielmo, G., Larrosa, E., & George, O. (2019) · European Neuropsychopharmacology

Smoking Behavior and CessationNicotinic Acetylcholine Receptors Study

Cited by 25