Stanger, Ben Z.

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

Costa-Silva, B., Aiello, N. M., Ocean, A. J., Singh, S., Zhang, H., Thakur, B. K., Becker, A., Hoshino, A., Mark, M. T., Molina, H., et al. (2015) · Nature Cell Biology

Extracellular vesicles in diseasePancreatic and Hepatic Oncology Research

Cited by 2,692

Guidelines and definitions for research on epithelial-mesenchymal transition

Yang, J., Antin, P., Berx, G., Blanpain, C., Brabletz, T., Bronner, M., Campbell, K., Cano, A., Casanova, J., Christofori, G., et al. (2020) · Nature Reviews Molecular Cell Biology

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 2,226

EMT and Dissemination Precede Pancreatic Tumor Formation

Rhim, A. D., Mirek, E. T., Aiello, N. M., Maitra, A., Bailey, J. M., McAllister, F., Reichert, M., Beatty, G. L., Rustgi, A. K., Vonderheide, R. H., et al. (2012) · Cell

Cancer Cells and MetastasisPancreatic and Hepatic Oncology Research

Cited by 2,136

Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma

Rhim, A. D., Oberstein, P. E., Thomas, D. H., Mirek, E. T., Palermo, C. F., Sastra, S. A., Dekleva, E. N., Saunders, T., Becerra, C. P., Tattersall, I. W., et al. (2014) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchHedgehog Signaling Pathway Studies

Cited by 2,085

The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal

Kelliher, M. A., Grimm, S., Ishida, Y., Kuo, F., Stanger, B. Z., & Leder, P. (1998) · Immunity

NF-κB Signaling PathwaysCell death mechanisms and regulation

Cited by 1,102

Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer

Bayne, L. J., Beatty, G. L., Jhala, N., Clark, C. E., Rhim, A. D., Stanger, B. Z., & Vonderheide, R. H. (2012) · Cancer Cell

Immune cells in cancerPancreatic and Hepatic Oncology Research

Cited by 947

Hippo Pathway Activity Influences Liver Cell Fate

Yimlamai, D., Christodoulou, C., Galli, G. G., Yanger, K., Pepe-Mooney, B., Gurung, B., Shrestha, K., Cahan, P., Stanger, B. Z., & Camargo, F. D. (2014) · Cell

Hippo pathway signaling and YAP/TAZLiver physiology and pathology

Cited by 857

Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation

Lee, J. V., Carrer, A., Shah, S., Snyder, N. W., Wei, S., Venneti, S., Worth, A. J., Yuan, Z.-F., Lim, H.-W., Liu, S., et al. (2014) · Cell Metabolism

Cancer, Lipids, and MetabolismCancer, Hypoxia, and Metabolism

Cited by 563

Robust cellular reprogramming occurs spontaneously during liver regeneration

Yanger, K., Zong, Y., Maggs, L. R., Shapira, S. N., Maddipati, R., Aiello, N. M., Thung, S. N., Wells, R. G., Greenbaum, L. E., & Stanger, B. Z. (2013) · Genes & Development

Liver physiology and pathologyDevelopmental Biology and Gene Regulation

Cited by 484

Induction of T-cell immunity overcomes complete resistance to PD-1 and CTLA-4 blockade and improves survival in pancreatic carcinoma

Winograd, R., Byrne, K. T., Evans, R. A., Odorizzi, P. M., Meyer, A. R. L., Bajor, D. L., Clendenin, C., Stanger, B. Z., Furth, E. E., Wherry, E. J., et al. (2015) · Cancer Immunology Research

Cancer Immunotherapy and BiomarkersPancreatic and Hepatic Oncology Research

Cited by 459

Adult Hepatocytes Are Generated by Self-Duplication Rather than Stem Cell Differentiation

Yanger, K., Knigin, D., Zong, Y., Maggs, L., Gu, G., Akiyama, H., Pikarsky, E., & Stanger, B. Z. (2014) · Cell Stem Cell

Liver physiology and pathologyMesenchymal stem cell research

Cited by 426

Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer

Ruscetti, M., Morris, J. P., Mezzadra, R., Russell, J., Leibold, J., Romesser, P. B., Simon, J., Kulick, A., Ho, Y.-J., Fennell, M., et al. (2020) · Cell

Pancreatic and Hepatic Oncology ResearchTelomeres, Telomerase, and Senescence

Cited by 424

Efficacy of a small-molecule inhibitor of KrasG12D in immunocompetent models of pancreatic cancer

Kemp, S. B., Cheng, N., Markosyan, N., Sor, R., Kim, I.-K., Hallin, J., Shoush, J., Quinones, L., Brown, N. V., Bassett, J. B., et al. (2023) · Cancer Discovery

Pancreatic and Hepatic Oncology ResearchProtein Kinase Regulation and GTPase Signaling

Cited by 370

Adult cell plasticity in vivo: de-differentiation and transdifferentiation are back in style

Merrell, A. J., & Stanger, B. Z. (2016) · Nature Reviews Molecular Cell Biology

Pluripotent Stem Cells ResearchMesenchymal stem cell research

Cited by 369

Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts

Bhattacharjee, S., Hamberger, F., Ravichandra, A., Miller, M., Nair, A., Affo, S., Filliol, A., Chin, L., Savage, T. M., Yin, D., et al. (2021) · Journal of Clinical Investigation

Cancer Cells and MetastasisCellular Mechanics and Interactions

Cited by 367

The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer

Mirji, G., Worth, A., Bhat, S. A., El Sayed, M., Kannan, T., Goldman, A. R., Tang, H.-Y., Liu, Q., Auslander, N., Dang, C. V., et al. (2022) · Science Immunology

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 327

Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis

Carrer, A., Trefely, S., Zhao, S., Campbell, S. L., Norgard, R. J., Schultz, K. C., Sidoli, S., Parris, J. L. D., Affronti, H. C., Sivanand, S., et al. (2019) · Cancer Discovery

Cancer, Lipids, and MetabolismPancreatic and Hepatic Oncology Research

Cited by 313

Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer

Dilly, J., Hoffman, M. T., Abbassi, L., Li, Z., Paradiso, F., Parent, B. D., Hennessey, C. J., Jordan, A. C., Morgado, M., Dasgupta, S., et al. (2024) · Cancer Discovery

Pancreatic and Hepatic Oncology ResearchProtein Kinase Regulation and GTPase Signaling

Cited by 308

Combining Machine Learning and Nanofluidic Technology To Diagnose Pancreatic Cancer Using Exosomes

Ko, J., Bhagwat, N., Yee, S. S., Ortiz, N., Sahmoud, A., Black, T., Aiello, N. M., McKenzie, L., O’Hara, M., Redlinger, C., et al. (2017) · ACS Nano

Extracellular vesicles in diseaseMicrofluidic and Capillary Electrophoresis Applications

Cited by 249

Cellular Homeostasis and Repair in the Mammalian Liver

Stanger, B. Z. (2015) · Annual Review of Physiology

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 248

Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer

Wasko, U. N., Jiang, J., Dalton, T. C., Curiel-Garcia, A., Edwards, A. C., Wang, Y., Lee, B., Orlen, M., Tian, S., Stalnecker, C. A., et al. (2024) · Nature

Pancreatic and Hepatic Oncology ResearchProtein Kinase Regulation and GTPase Signaling

Cited by 209

A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling

Nguyen, D.-H. T., Lee, E., Alimperti, S., Norgard, R. J., Wong, A., Lee, J. J.-K., Eyckmans, J., Stanger, B. Z., & Chen, C. S. (2019) · Science Advances

Pancreatic and Hepatic Oncology ResearchAngiogenesis and VEGF in Cancer

Cited by 172

The prrx1 homeodomain transcription factor plays a central role in pancreatic regeneration and carcinogenesis

Reichert, M., Takano, S., von Burstin, J., Kim, S.-B., Lee, J.-S., Ihida-Stansbury, K., Hahn, C., Heeg, S., Schneider, G., Rhim, A. D., et al. (2013) · Genes & Development

Pancreatic and Hepatic Oncology ResearchPancreatic function and diabetes

Cited by 112

Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer

Brown, W. S., McDonald, P. C., Nemirovsky, O., Awrey, S., Chafe, S. C., Schaeffer, D. F., Li, J., Renouf, D. J., Stanger, B. Z., & Dedhar, S. (2020) · Cell Reports Medicine

PI3K/AKT/mTOR signaling in cancerPancreatic and Hepatic Oncology Research

Cited by 111