Howell, Anthony

Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial

Cuzick, J., Sestak, I., Baum, M., Buzdar, A., Howell, A., Dowsett, M., & Forbes, J. F. (2010) · The Lancet Oncology

Breast Cancer Treatment StudiesEstrogen and related hormone effects

Cited by 1,674

The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women

Harvie, M. N., Pegington, M., Mattson, M. P., Frystyk, J., Dillon, B., Evans, G., Cuzick, J., Jebb, S. A., Martin, B., Cutler, R. G., et al. (2011) · International Journal of Obesity

Dietary Effects on HealthNutritional Studies and Diet

Cited by 804

Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial

Cuzick, J., Sestak, I., Forbes, J. F., Dowsett, M., Knox, J., Cawthorn, S., Saunders, C., Roche, N., Mansel, R. E., von Minckwitz, G., et al. (2014) · The Lancet

Breast Cancer Treatment StudiesCancer Risks and Factors

Cited by 590

The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women

Harvie, M., Wright, C., Pegington, M., McMullan, D., Mitchell, E., Martin, B., Cutler, R. G., Evans, G., Whiteside, S., Maudsley, S., et al. (2013) · British Journal Of Nutrition

Dietary Effects on HealthDiet and metabolism studies

Cited by 431

Anastrozole, a potent and selective aromatase inhibitor, versus megestrol acetate in postmenopausal women with advanced breast cancer: results of overview analysis of two phase III trials. Arimidex Study Group.

Buzdar, A., Jonat, W., Howell, A., Jones, S. E., Blomqvist, C., Vogel, C. L., Eiermann, W., Wolter, J. M., Azab, M., Webster, A., et al. (1996) · Journal of Clinical Oncology

Breast Cancer Treatment StudiesAdvanced Breast Cancer Therapies

Cited by 406

Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, multicentre, phase 3 randomised trial

Johnston, S. R., Kilburn, L. S., Ellis, P., Dodwell, D., Cameron, D., Hayward, L., Im, Y.-H., Braybrooke, J. P., Brunt, A. M., Cheung, K.-L., et al. (2013) · The Lancet Oncology

Advanced Breast Cancer TherapiesBreast Cancer Treatment Studies

Cited by 274

Mammographic density adds accuracy to both the Tyrer-Cuzick and Gail breast cancer risk models in a prospective UK screening cohort

Brentnall, A. R., Harkness, E. F., Astley, S. M., Donnelly, L. S., Stavrinos, P., Sampson, S., Fox, L., Sergeant, J. C., Harvie, M. N., Wilson, M., et al. (2015) · Breast Cancer Research

Digital Radiography and Breast ImagingGlobal Cancer Incidence and Screening

Cited by 252

Stromal-epithelial metabolic coupling in cancer: integrating autophagy and metabolism in the tumor microenvironment

Martinez-Outschoorn, U. E., Pavlides, S., Howell, A., Pestell, R. G., Tanowitz, H. B., Sotgia, F., & Lisanti, M. P. (2011) · The International Journal of Biochemistry & Cell Biology

Cancer, Hypoxia, and MetabolismAutophagy in Disease and Therapy

Cited by 248

Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast

McMichael-Phillips, D. F., Harding, C., Morton, M., Roberts, S. A., Howell, A., Potten, C. S., & Bundred, N. J. (1998) · The American Journal of Clinical Nutrition

Phytoestrogen effects and researchEstrogen and related hormone effects

Cited by 241

Tamoxifen (‘Nolvadex’): a review

Clemons, M., Danson, S., & Howell, A. (2002) · Cancer Treatment Reviews

Breast Cancer Treatment StudiesEstrogen and related hormone effects

Cited by 229

CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis

Capparelli, C., Chiavarina, B., Whitaker-Menezes, D., Pestell, T. G., Pestell, R. G., Hulit, J., Andò, S., Howell, A., Martinez-Outschoorn, U. E., Sotgia, F., et al. (2012) · Cell Cycle

Telomeres, Telomerase, and SenescenceAutophagy in Disease and Therapy

Cited by 221

Understanding the "lethal" drivers of tumor-stroma co-evolution: Emerging role(s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor microenvironment

Lisanti, M. P., Martinez-Outschoorn, U. E., Chiavarina, B., Pavlides, S., Whitaker-Menezes, D., Tsirigos, A., Witkiewicz, A. K., Lin, Z., Balliet, R. M., Howell, A., et al. (2010) · Cancer Biology & Therapy

Cancer, Hypoxia, and MetabolismAutophagy in Disease and Therapy

Cited by 199

Contralateral mastectomy improves survival in women with BRCA1/2-associated breast cancer

Evans, D. G. R., Ingham, S. L., Baildam, A., Ross, G. L., Lalloo, F., Buchan, I., & Howell, A. (2013) · Breast Cancer Research and Treatment

BRCA gene mutations in cancerMultiple and Secondary Primary Cancers

Cited by 178

Potential Benefits and Harms of Intermittent Energy Restriction and Intermittent Fasting Amongst Obese, Overweight and Normal Weight Subjects—A Narrative Review of Human and Animal Evidence

Harvie, M., & Howell, A. (2017) · Behavioral Sciences

Dietary Effects on HealthDiet and metabolism studies

Cited by 174

Energy transfer in "parasitic" cancer metabolism: Mitochondria are the powerhouse and Achilles' heel of tumor cells

Martinez-Outschoorn, U. E., Pestell, R. G., Howell, A., Tykocinski, M. L., Nagajyothi, F., Machado, F. S., Tanowitz, H. B., Sotgia, F., & Lisanti, M. P. (2011) · Cell Cycle

Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism

Cited by 157

Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: Evidence for stromal-epithelial metabolic coupling

Migneco, G., Whitaker-Menezes, D., Chiavarina, B., Castello-Cros, R., Pavlides, S., Pestell, R. G., Fatatis, A., Flomenberg, N., Tsirigos, A., Howell, A., et al. (2010) · Cell Cycle

Cancer, Hypoxia, and MetabolismCancer Cells and Metastasis

Cited by 153

Red clover isoflavones are safe and well tolerated in women with a family history of breast cancer

Powles, T. J., Howell, A., Evans, D. G., Mccloskey, E. V., Ashley, S., Greenhalgh, R., Affen, J., Flook, L. A., & Tidy, A. (2008) · Menopause International

Phytoestrogen effects and researchMenopause: Health Impacts and Treatments

Cited by 75

Long-term outcomes of breast cancer in women aged 30 years or younger, based on family history, pathology and BRCA1/BRCA2/TP53 status

Evans, D. G. R., Moran, A., Hartley, R., Dawson, J., Bulman, B., Knox, F., Howell, A., & Lalloo, F. (2010) · British Journal of Cancer

BRCA gene mutations in cancerBreast Cancer Treatment Studies

Cited by 52

Participant-Reported Symptoms and Their Effect on Long-Term Adherence in the International Breast Cancer Intervention Study I (IBIS I)

Smith, S. G., Sestak, I., Howell, A., Forbes, J., & Cuzick, J. (2017) · Journal of Clinical Oncology

Medication Adherence and ComplianceCancer survivorship and care

Cited by 51

Breast cancer risk status influences uptake, retention and efficacy of a weight loss programme amongst breast cancer screening attendees: Two randomised controlled feasibility trials

Harvie, M., Pegington, M., French, D., Cooper, G., McDiarmid, S., Howell, A., Donnelly, L., Ruane, H., Sellers, K., Foden, P., et al. (2019) · BMC Cancer

Cancer Risks and FactorsGlobal Cancer Incidence and Screening

Cited by 34

Early participant-reported symptoms as predictors of adherence to anastrozole in the International Breast Cancer Intervention Studies II

Sestak, I., Smith, S. G., Howell, A., Forbes, J. F., & Cuzick, J. (2018) · Annals of Oncology

Medication Adherence and ComplianceBreast Cancer Treatment Studies

Cited by 27