Golde, Todd E.

Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Aβ levels

Lawlor, P. A., Bland, R. J., Das, P., Price, R. W., Holloway, V., Smithson, L., Dicker, B. L., During, M. J., Young, D., & Golde, T. E. (2007) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 67

Immunotherapies for Alzheimer’s disease

Golde, T. E., & Levey, A. I. (2023) · Science

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 66

Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits

Xu, G., Ran, Y., Fromholt, S. E., Fu, C., Yachnis, A. T., Golde, T. E., & Borchelt, D. R. (2015) · Acta Neuropathologica Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 65

Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy

Koller, E. J., Gonzalez De La Cruz, E., Machula, T., Ibanez, K. R., Lin, W.-L., Williams, T., Riffe, C. J., Ryu, D., Strang, K. H., Liu, X., et al. (2019) · Human Molecular Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 63

Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice

Ceballos-Diaz, C., Rosario, A. M., Park, H.-J., Chakrabarty, P., Sacino, A., Cruz, P. E., Siemienski, Z., Lara, N., Moran, C., Ravelo, N., et al. (2015) · Molecular Neurodegeneration

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 58

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

Carrasquillo, M. M., Allen, M., Burgess, J. D., Wang, X., Strickland, S. L., Aryal, S., Siuda, J., Kachadoorian, M. L., Medway, C., Younkin, C. S., et al. (2017) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 58

Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration

Sorrentino, Z. A., Xia, Y., Funk, C., Riffe, C. J., Rutherford, N. J., Ceballos Diaz, C., Sacino, A. N., Price, N. D., Golde, T. E., Giasson, B. I., et al. (2018) · Neurobiology of Disease

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 54

Large‐scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity

Seifar, F., Fox, E. J., Shantaraman, A., Liu, Y., Dammer, E. B., Modeste, E., Duong, D. M., Yin, L., Trautwig, A. N., Guo, Q., et al. (2024) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 52

Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection

Yang, F., Beltran-Lobo, P., Sung, K., Goldrick, C., Croft, C. L., Nishimura, A., Hedges, E., Mahiddine, F., Troakes, C., Golde, T. E., et al. (2024) · Science Advances

Heat shock proteins researchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 46

Quantitative and Mechanistic Studies of Aβ Immunotherapy

Golde, T., Das, P., & Levites, Y. (2009) · CNS & Neurological Disorders - Drug Targets

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 46

Harnessing Immunoproteostasis to Treat Neurodegenerative Disorders

Golde, T. E. (2019) · Neuron

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 45

IFN‐γ promotes τ phosphorylation without affecting mature tangles

Li, A., Ceballos‐Diaz, C., DiNunno, N., Levites, Y., Cruz, P. E., Lewis, J., Golde, T. E., & Chakrabarty, P. (2015) · The FASEB Journal

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 43

Neurite orientation dispersion and density imaging reveals white matter and hippocampal microstructure changes produced by Interleukin-6 in the TgCRND8 mouse model of amyloidosis

Colon-Perez, L. M., Ibanez, K. R., Suarez, M., Torroella, K., Acuna, K., Ofori, E., Levites, Y., Vaillancourt, D. E., Golde, T. E., Chakrabarty, P., et al. (2019) · NeuroImage

Advanced Neuroimaging Techniques and ApplicationsAlzheimer's disease research and treatments

Cited by 41

High throughput screens for the identification of compounds that alter the accumulation of the Alzheimer's amyloid β peptide (Aβ)

Haugabook, S. J., Yager, D. M., Eckman, E. A., Golde, T. E., Younkin, S. G., & Eckman, C. B. (2001) · Journal of Neuroscience Methods

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 39

Age-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis

Hanna, A., Iremonger, K., Das, P., Dickson, D., Golde, T., & Janus, C. (2012) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsMemory and Neural Mechanisms

Cited by 38

Genetic architecture of plasma Alzheimer disease biomarkers

Bradley, J., Gorijala, P., Schindler, S. E., Sung, Y. J., Ances, B., the Alzheimer’s Disease Neuroimaging Initiative, T. H. C. P., Ertekin-Taner, N., Younkin, S., Golde, T., Price, N., et al. (2023) · Human Molecular Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 20

Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways

Ibanez, K. R., McFarland, K. N., Phillips, J., Allen, M., Lessard, C. B., Zobel, L., De La Cruz, E. G., Shah, S., Vo, Q., Wang, X., et al. (2022) · Alzheimer's Research & Therapy

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 18

In vivo cortical diffusion imaging relates to Alzheimer's disease neuropathology

Torso, M., Ridgway, G. R., Valotti, M., Hardingham, I., Chance, S. A., for the National Alzheimer’s Coordinating Center, Brewer, J., Lopez, O., Hyman, B., Grabowski, T., et al. (2023) · Alzheimer's Research & Therapy

Dementia and Cognitive Impairment ResearchAdvanced Neuroimaging Techniques and Applications

Cited by 16