Brech, Andreas

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

Pankiv, S., Clausen, T. H., Lamark, T., Brech, A., Bruun, J.-A., Outzen, H., Øvervatn, A., Bjørkøy, G., & Johansen, T. (2007) · Journal of Biological Chemistry

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

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Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Bjørkøy, G., Lamark, T., Brech, A., Outzen, H., Perander, M., Øvervatn, A., Stenmark, H., & Johansen, T. (2005) · The Journal of Cell Biology

Autophagy in Disease and TherapyGenetic Neurodegenerative Diseases

Cited by 3,276

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

Simonsen, A., Lippe, R., Christoforidis, S., Gaullier, J.-M., Brech, A., Callaghan, J., Toh, B.-H., Murphy, C., Zerial, M., & Stenmark, H. (1998) · Nature

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 1,133

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

Simonsen, A., Cumming, R. C., Brech, A., Isakson, P., Schubert, D. R., & Finley, K. D. (2008) · Autophagy

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

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Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

Filimonenko, M., Stuffers, S., Raiborg, C., Yamamoto, A., Malerød, L., Fisher, E. M. C., Isaacs, A., Brech, A., Stenmark, H., & Simonsen, A. (2007) · The Journal of Cell Biology

Autophagy in Disease and TherapyCellular transport and secretion

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Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain

Nezis, I. P., Simonsen, A., Sagona, A. P., Finley, K., Gaumer, S., Contamine, D., Rusten, T. E., Stenmark, H., & Brech, A. (2008) · The Journal of Cell Biology

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

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PIKfyve inhibition increases exosome release and induces secretory autophagy

Hessvik, N. P., Øverbye, A., Brech, A., Torgersen, M. L., Jakobsen, I. S., Sandvig, K., & Llorente, A. (2016) · Cellular and Molecular Life Sciences

Extracellular vesicles in diseaseCellular transport and secretion

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Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis

Nezis, I. P., Shravage, B. V., Sagona, A. P., Lamark, T., Bjørkøy, G., Johansen, T., Rusten, T. E., Brech, A., Baehrecke, E. H., & Stenmark, H. (2010) · Journal of Cell Biology

Autophagy in Disease and TherapyCell death mechanisms and regulation

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ESCRT-mediated phagophore sealing during mitophagy

Zhen, Y., Spangenberg, H., Munson, M. J., Brech, A., Schink, K. O., Tan, K.-W., Sørensen, V., Wenzel, E. M., Radulovic, M., Engedal, N., et al. (2020) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

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Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy

Nezis, I. P., Lamark, T., Velentzas, A. D., Rusten, T. E., Bjørkøy, G., Johansen, T., Papassideri, I. S., Stravopodis, D. J., Margaritis, L. H., Stenmark, H., et al. (2009) · Autophagy

Autophagy in Disease and TherapyCell death mechanisms and regulation

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Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites

Holdgaard, S. G., Cianfanelli, V., Pupo, E., Lambrughi, M., Lubas, M., Nielsen, J. C., Eibes, S., Maiani, E., Harder, L. M., Wesch, N., et al. (2019) · Nature Communications

Microtubule and mitosis dynamicsAutophagy in Disease and Therapy

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Intracellular Mycobacterium avium Intersect Transferrin in the Rab11+Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway

Halaas, Ø., Steigedal, M., Haug, M., Awuh, J. A., Ryan, L., Brech, A., Sato, S., Husebye, H., Cangelosi, G. A., Akira, S., et al. (2010) · The Journal of Infectious Diseases

Mycobacterium research and diagnosisTuberculosis Research and Epidemiology

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