Scully, Ralph

The repertoire of mutational signatures in human cancer

Alexandrov, L. B., Kim, J., Haradhvala, N. J., Huang, M. N., Tian Ng, A. W., Wu, Y., Boot, A., Covington, K. R., Gordenin, D. A., Bergstrom, E. N., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 3,496

Pan-cancer analysis of whole genomes

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Aaltonen, L. A., Abascal, F., Abeshouse, A., Aburatani, H., Adams, D. J., Agrawal, N., Ahn, K. S., Ahn, S.-M., Aikata, H., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 3,064

Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells

Scully, R., Chen, J., Plug, A., Xiao, Y., Weaver, D., Feunteun, J., Ashley, T., & Livingston, D. M. (1997) · Cell

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 1,459

The evolutionary history of 2,658 cancers

Gerstung, M., Jolly, C., Leshchiner, I., Dentro, S. C., Gonzalez, S., Rosebrock, D., Mitchell, T. J., Rubanova, Y., Anur, P., Yu, K., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 1,057

Involvement of the TIP60 Histone Acetylase Complex in DNA Repair and Apoptosis

Ikura, T., Ogryzko, V. V., Grigoriev, M., Groisman, R., Wang, J., Horikoshi, M., Scully, R., Qin, J., & Nakatani, Y. (2000) · Cell

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 1,029

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

Scully, R., Chen, J., Ochs, R. L., Keegan, K., Hoekstra, M., Feunteun, J., & Livingston, D. M. (1997) · Cell

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 900

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

Oberdoerffer, P., Michan, S., McVay, M., Mostoslavsky, R., Vann, J., Park, S.-K., Hartlerode, A., Stegmuller, J., Hafner, A., Loerch, P., et al. (2008) · Cell

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 852

In search of the tumour-suppressor functions of BRCA1 and BRCA2

Scully, R., & Livingston, D. M. (2000) · Nature

BRCA gene mutations in cancerDNA Repair Mechanisms

Cited by 643

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

Tibbetts, R. S., Cortez, D., Brumbaugh, K. M., Scully, R., Livingston, D., Elledge, S. J., & Abraham, R. T. (2000) · Genes & Development

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 512

Genetic Analysis of BRCA1 Function in a Defined Tumor Cell Line

Scully, R., Ganesan, S., Vlasakova, K., Chen, J., Socolovsky, M., & Livingston, D. M. (1999) · Molecular Cell

BRCA gene mutations in cancerDNA Repair Mechanisms

Cited by 359

Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion

Juvekar, A., Hu, H., Yadegarynia, S., Lyssiotis, C. A., Ullas, S., Lien, E. C., Bellinger, G., Son, J., Hok, R. C., Seth, P., et al. (2016) · Proceedings of the National Academy of Sciences

PARP inhibition in cancer therapyPI3K/AKT/mTOR signaling in cancer

Cited by 93

H2AX post-translational modifications in the ionizing radiation response and homologous recombination

Xie, A., Odate, S., Chandramouly, G., & Scully, R. A. (2010) · Cell Cycle

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 59

Lamin B1 sequesters 53BP1 to control its recruitment to DNA damage

Etourneaud, L., Moussa, A., Rass, E., Genet, D., Willaume, S., Chabance-Okumura, C., Wanschoor, P., Picotto, J., Thézé, B., Dépagne, J., et al. (2021) · Science Advances

DNA Repair MechanismsNuclear Structure and Function

Cited by 54