Ethell, Iryna M.

Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model

Bilousova, T. V., Dansie, L., Ngo, M., Aye, J., Charles, J. R., Ethell, D. W., & Ethell, I. M. (2009) · Journal of Medical Genetics

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 465

Matrix metalloproteinases in brain development and remodeling: Synaptic functions and targets

Ethell, I. M., & Ethell, D. W. (2007) · Journal of Neuroscience Research

Protease and Inhibitor MechanismsNeuroscience and Neuropharmacology Research

Cited by 378

EphB/syndecan-2 signaling in dendritic spine morphogenesis

Ethell, I. M., Irie, F., Kalo, M. S., Couchman, J. R., Pasquale, E. B., & Yamaguchi, Y. (2001) · Neuron

Axon Guidance and Neuronal SignalingNeuroscience and Neuropharmacology Research

Cited by 309

Open-label add-on treatment trial of minocycline in fragile X syndrome.

Paribello, C., Tao, L., Folino, A., Berry-Kravis, E., Tranfaglia, M., Ethell, I. M., & Ethell, D. W. (2010) · BMC Neurology

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 223

A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders.

Reinhard, S. M., Razak, K., & Ethell, I. M. (2015) · Frontiers in Cellular Neuroscience

Genetics and Neurodevelopmental DisordersProtease and Inhibitor Mechanisms

Cited by 219

Cell surface heparan sulfate proteoglycan syndecan-2 induces the maturation of dendritic spines in rat hippocampal neurons.

Ethell, I. M., & Yamaguchi, Y. (1999) · The Journal of Cell Biology

Neuroscience and Neuropharmacology ResearchProteoglycans and glycosaminoglycans research

Cited by 209

Integrins Control Dendritic Spine Plasticity in Hippocampal Neurons through NMDA Receptor and Ca2+/Calmodulin-Dependent Protein Kinase II-Mediated Actin Reorganization

Shi, Y., & Ethell, I. M. (2006) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchCell Adhesion Molecules Research

Cited by 200

The Perineuronal ‘Safety’ Net? Perineuronal Net Abnormalities in Neurological Disorders

Wen, T. H., Binder, D. K., Ethell, I. M., & Razak, K. A. (2018) · Frontiers in Molecular Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 170

Genetic Reduction of Matrix Metalloproteinase-9 Promotes Formation of Perineuronal Nets Around Parvalbumin-Expressing Interneurons and Normalizes Auditory Cortex Responses in Developing Fmr1 Knock-Out Mice

Wen, T. H., Afroz, S., Reinhard, S. M., Palacios, A. R., Tapia, K., Binder, D. K., Razak, K. A., & Ethell, I. M. (2018) · Cerebral Cortex

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 165

Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile X syndrome in a mouse model

Sidhu, H., Dansie, L. E., Hickmott, P. W., Ethell, D. W., & Ethell, I. M. (2014) · Journal of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 155

Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome.

Lovelace, J. W., Ethell, I. M., Binder, D. K., & Razak, K. A. (2018) · Neurobiology of Disease

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 154

Minocycline treatment reverses ultrasonic vocalization production deficit in a mouse model of Fragile X Syndrome

Rotschafer, S. E., Trujillo, M. S., Dansie, L. E., Ethell, I. M., & Razak, K. A. (2012) · Brain Research

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 130

Matrix metalloproteinase-9 deletion rescues auditory evoked potential habituation deficit in a mouse model of Fragile X Syndrome

Lovelace, J. W., Wen, T. H., Reinhard, S., Hsu, M. S., Sidhu, H., Ethell, I. M., Binder, D. K., & Razak, K. A. (2016) · Neurobiology of Disease

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 115

Side Effects of Minocycline Treatment in Patients With Fragile X Syndrome and Exploration of Outcome Measures

Utari, A., Chonchaiya, W., Rivera, S. M., Schneider, A., Hagerman, R. J., Faradz, S. M. H., Ethell, I. M., & Nguyen, D. V. (2010) · American Journal on Intellectual and Developmental Disabilities

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 105

Matrix metalloproteinase‐7 disrupts dendritic spines in hippocampal neurons through NMDA receptor activation

Bilousova, T. V., Rusakov, D. A., Ethell, D. W., & Ethell, I. M. (2006) · Journal of Neurochemistry

Neuroscience and Neuropharmacology ResearchProtease and Inhibitor Mechanisms

Cited by 98

Long-lasting effects of minocycline on behavior in young but not adult Fragile X mice.

Dansie, L. E., Phommahaxay, K., Okusanya, A. G., Uwadia, J., Huang, M., Rotschafer, S. E., Razak, K. A., Ethell, D. W., & Ethell, I. M. (2013) · Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 95

Acute pharmacological inhibition of matrix metalloproteinase‐9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice

Pirbhoy, P. S., Rais, M., Lovelace, J. W., Woodard, W., Razak, K. A., Binder, D. K., & Ethell, I. M. (2020) · Journal of Neurochemistry

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 62

Urokinase plasminogen activator mediates changes in human astrocytes modeling fragile X syndrome

Peteri, U., Pitkonen, J., de Toma, I., Nieminen, O., Utami, K. H., Strandin, T. M., Corcoran, P., Roybon, L., Vaheri, A., Ethell, I., et al. (2021) · Glia

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 16

An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis

Talvio, K., Wagner, V. A., Minkeviciene, R., Kirkwood, J. S., Kulinich, A. O., Umemori, J., Bhatia, A., Hur, M., Käkelä, R., Ethell, I. M., et al. (2023) · Communications Biology

Genetics and Neurodevelopmental DisordersCholesterol and Lipid Metabolism

Cited by 8