Chaker, Layal

Hypothyroidism

Chaker, L., Bianco, A. C., Jonklaas, J., & Peeters, R. P. (2017) · The Lancet

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 1,159

Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis

The Consortium on Thyroid and Pregnancy—Study Group on Preterm Birth, Korevaar, T. I. M., Derakhshan, A., Taylor, P. N., Meima, M., Chen, L., Bliddal, S., Carty, D. M., Meems, M., Vaidya, B., et al. (2019) · JAMA

Thyroid Disorders and TreatmentsReproductive System and Pregnancy

Cited by 378

Hypothyroidism

Chaker, L., Razvi, S., Bensenor, I. M., Azizi, F., Pearce, E. N., & Peeters, R. P. (2022) · Nature Reviews Disease Primers

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 330

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Teumer, A., Chaker, L., Groeneweg, S., Li, Y., Di Munno, C., Barbieri, C., Schultheiss, U. T., Traglia, M., Ahluwalia, T. S., Akiyama, M., et al. (2018) · Nature Communications

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 280

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease

Medici, M., Porcu, E., Pistis, G., Teumer, A., Brown, S. J., Jensen, R. A., Rawal, R., Roef, G. L., Plantinga, T. S., Vermeulen, S. H., et al. (2014) · PLoS Genetics

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 218

Thyroid function and the risk of nonalcoholic fatty liver disease: the Rotterdam study

Bano, A., Chaker, L., Plompen, E. P. C., Hofman, A., Dehghan, A., Franco, O. H., Janssen, H. L. A., Murad, S. D., & Peeters, R. P. (2016) · The Journal of Clinical Endocrinology & Metabolism

Liver Disease Diagnosis and TreatmentThyroid Disorders and Treatments

Cited by 209

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

Zhou, W., Brumpton, B., Kabil, O., Gudmundsson, J., Thorleifsson, G., Weinstock, J., Zawistowski, M., Nielsen, J. B., Chaker, L., Medici, M., et al. (2020) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 129

Thyroid function characteristics and determinants: the Rotterdam study.

Chaker, L., Korevaar, T. I. M., Medici, M., Uitterlinden, A. G., Hofman, A., Dehghan, A., Franco, O. H., & Peeters, R. P. (2016) · Thyroid

Thyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment

Cited by 118

Thyroid Function and Sudden Cardiac Death: A Prospective Population-Based Cohort Study

Chaker, L., van den Berg, M. E., Niemeijer, M. N., Franco, O. H., Dehghan, A., Hofman, A., Rijnbeek, P. R., Deckers, J. W., Eijgelsheim, M., Stricker, B. H. C., et al. (2016) · Circulation

Thyroid Disorders and TreatmentsCardiac electrophysiology and arrhythmias

Cited by 97

Clinical aspects of thyroid function during ageing

Chaker, L., Cappola, A. R., Mooijaart, S. P., & Peeters, R. P. (2018) · The Lancet Diabetes & Endocrinology

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 94

Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis

Chaker, L., Baumgartner, C., den Elzen, W. P. J., Collet, T.-H., Ikram, M. A., Blum, M. R., Dehghan, A., Drechsler, C., Luben, R. N., Portegies, M. L. P., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsAcute Ischemic Stroke Management

Cited by 92

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications.

Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., et al. (2024) · Nature Communications

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 79

Subclinical thyroid dysfunction and the risk of stroke: a systematic review and meta-analysis

Chaker, L., Baumgartner, C., Ikram, M. A., Dehghan, A., Medici, M., Visser, W. E., Hofman, A., Rodondi, N., Peeters, R. P., & Franco, O. H. (2014) · European Journal of Epidemiology

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 72

Type 2 diabetes partitioned polygenic scores associate with disease outcomes in 454,193 individuals across 13 cohorts

DiCorpo, D., LeClair, J., Cole, J. B., Sarnowski, C., Ahmadizar, F., Bielak, L. F., Blokstra, A., Bottinger, E. P., Chaker, L., Chen, Y.-D. I., et al. (2022) · Diabetes Care

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 66

Association of Thyroid Function With Life Expectancy With and Without Cardiovascular Disease: The Rotterdam Study

Bano, A., Dhana, K., Chaker, L., Kavousi, M., Ikram, M. A., Mattace-Raso, F. U. S., Peeters, R. P., & Franco, O. H. (2017) · JAMA Internal Medicine

Thyroid Disorders and TreatmentsHormonal and reproductive studies

Cited by 64

Hypothyroidism: A Review

Chaker, L., & Papaleontiou, M. (2025) · JAMA

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 63

The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis

Xu, Y., Derakhshan, A., Hysaj, O., Wildisen, L., Ittermann, T., Pingitore, A., Abolhassani, N., Medici, M., Kiemeney, L. A. L. M., Riksen, N. P., et al. (2023) · The Lancet Diabetes & Endocrinology

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 61

A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans

McAninch, E. A., Rajan, K. B., Evans, D. A., Jo, S., Chaker, L., Peeters, R. P., Bennett, D. A., Mash, D. C., & Bianco, A. C. (2018) · The Journal of Clinical Endocrinology & Metabolism

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 59

Childhood Thyroid Function Reference Ranges and Determinants: A Literature Overview and a Prospective Cohort Study

Önsesveren, I., Barjaktarovic, M., Chaker, L., de Rijke, Y. B., Jaddoe, V. W. V., van Santen, H. M., Visser, T. J., Peeters, R. P., & Korevaar, T. I. M. (2017) · Thyroid®

Thyroid Disorders and TreatmentsClinical Laboratory Practices and Quality Control

Cited by 58

Thyroid Function Affects the Risk of Stroke via Atrial Fibrillation: A Mendelian Randomization Study

Marouli, E., Kus, A., Del Greco M, F., Chaker, L., Peeters, R., Teumer, A., Deloukas, P., & Medici, M. (2020) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 57

TSH and FT4 reference intervals in pregnancy: a systematic review and individual participant data meta-analysis

Osinga, J. A. J., Derakhshan, A., Palomaki, G. E., Ashoor, G., Männistö, T., Maraka, S., Chen, L., Bliddal, S., Lu, X., Taylor, P. N., et al. (2022) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsClinical Laboratory Practices and Quality Control

Cited by 54

A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations

Schultheiss, U. T., Teumer, A., Medici, M., Li, Y., Daya, N., Chaker, L., Homuth, G., Uitterlinden, A. G., Nauck, M., Hofman, A., et al. (2015) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 50

The Genetic Basis of Thyroid Function: Novel Findings and New Approaches

Kuś, A., Chaker, L., Teumer, A., Peeters, R. P., & Medici, M. (2020) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 44

Defining optimal health range for thyroid function based on the risk of cardiovascular disease

Chaker, L., Korevaar, T. I. M., Rizopoulos, D., Collet, T.-H., Völzke, H., Hofman, A., Rodondi, N., Cappola, A. R., Peeters, R. P., & Franco, O. H. (2017) · The Journal of Clinical Endocrinology & Metabolism

Thyroid Disorders and TreatmentsThyroid and Parathyroid Surgery

Cited by 33