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MBIP (MAP3K12 binding inhibitory protein) drives NSCLC metastasis by JNK-dependent activation of MMPs

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Discovering Genetic Factors for psoriasis through exhaustively searching for significant second order SNP-SNP interactions

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Single Cell Analysis of Human Thyroid Reveals the Transcriptional Signatures of Aging

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The Effects of Common Genetic Variation in 96 Genes Involved in Thyroid Hormone Regulation on TSH and FT4 Concentrations

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THE EFFECT OF RELAXIN ON THYROID WEIGHTS IN LABORATORY ANIMALS

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Compound hemizygous variants in SERPINA7 gene cause thyroxine‐binding globulin deficiency

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Hypothyroidism: A Review

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Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases

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Normal Values for the fT3/fT4 Ratio: Centile Charts (0–29 Years) and Their Application for the Differential Diagnosis of Children with Developmental Delay

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Thyroid dysfunction and cardiovascular disease

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The mediating role of thyroid-related hormones between thyroid dysfunction diseases and osteoporosis: a mediation mendelian randomization study

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Thyroid dysfunction in MASLD: Results of a nationwide study

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Free triiodothyronine and risk of gestational diabetes mellitus: an observational study and Mendelian randomization analysis

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The Intricate Relationship Between Thyroid Disorders and Type 2 Diabetes—A Narrative Review

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Causal association between thyroid function and the risk of infertility: a Mendelian randomization study

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Elevated thyroid-stimulating hormone levels, independent of Hashimoto’s thyroiditis, increase thyroid cancer risk: Insights from genetic and clinical evidence

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The Genetic Associations Between Kidney Stones, Obesity, Type 2 Diabetes, and Hypertension

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Deciphering thyroid function and CIMT: a Mendelian randomization study of the U-shaped influence mediated by apolipoproteins

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Association Between Autoimmune Thyroid disease and Oral Lichen Planus: A Multi-Omic Genetic Analysis

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Relationship Between Thyroid Hormones and Fat Distribution in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study

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Thyroid Dysfunction and Oral Lichen Planus: Evidence From Two-Sample Mendelian Randomization Analysis

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Increased risk of multisystem comorbidities and disease trajectories following hyperthyroidism: evidence from the 0.5 million UK Biobank population

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Investigating TSHR gene variants in consanguineous families: novel insights into variable expression in familial congenital hypothyroidism

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Impact of thyroid function on coagulation and venous thromboembolism: a two-sample mendelian randomization study

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Causal relationship between thyroid function and multiple sclerosis: A bidirectional Mendelian randomization study

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Association Between Free Triiodothyronine and Diabetic Peripheral Neuropathy in Euthyroid Patients With Type 2 Diabetes

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Genetic evidence suggests a causal relationship linking thyroid function to prospective memory and dementia and Parkinson’s disease

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Effects of thyroid-stimulating hormone and sensitivity to thyroid hormones on the risk of hyperuricemia in euthyroid adults

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Genetics of Thyroid Function: Relevance for Biology and Disease Management

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Multi-ancestry genome-wide association analyses provide insights into the genetic basis of Hashimoto’s thyroiditis

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Mendelian randomization analysis reveals no causal relationship between thyroid function and sarcopenia-related traits

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The Causal Role of Thyroid Hormones in Bipolar Disorders: A Two‐Sample Mendelian Randomization Study

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Thyroid Function and Brain Structure: Insight from a Mendelian Randomization Study

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Causal Associations Between Chronic Spontaneous Urticaria and Thyroid Function Indicators on Different Ethnic Groups: A Bidirectional Two‐Sample Mendelian Randomization Analysis

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Thyroid function and multiple sclerosis: a two-sample mendelian randomization study and mediation analysis

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Nonlinear association of TSH with pulmonary ventilation: insights from bidirectional Mendelian randomization and cross-sectional study

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Causal associations between thyroid function and sarcopenia-related traits: a Mendelian randomization study

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Thyroid function and amyotrophic lateral sclerosis: a mendelian randomization studyPreprint

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Thyroid dysfunction and pulmonary arterial hypertension: A bidirectional mendelian randomization study

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An Atlas of Genetic Correlations Between Thyroid Hormone Levels and Human Health‐Related Traits

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Machine learning model for predicting in-hospital cardiac mortality among atrial fibrillation patients

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Neighbourhood greenness might impact thyroid hormone levels in children, adolescents, and young adults

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Causal Association of Free Triiodothyronine Level with Ischemic Stroke Outcome: A Mendelian Randomization Study

Филимонов, Д. А., YEVTUSHENKO, S., Ishchenko, R. V., Eresko, A. B., Trubnikova, N. N., Луцкий, И., Belotserkovskaya, M., Александровна, К. И., Nosova, I., & Tereschenko, D. (2025) · Life · doi:10.3390/life15081303 · Cited by 1 · see citing works

Thyroid Disorders and Their Impact on Metabolic Syndrome and Cardiovascular Risk: A Narrative Review

Raveendran, A., Ragunathan, S., Neto, J. F. L., Mohamed, M. M., Chen, Y., Baral, S., Mendoza, A., Hatam, W., Yadav, S. K., Karvannan, V., et al. (2025) · Cureus · doi:10.7759/cureus.93669 · Cited by 3 · see citing works

Association between cardiometabolic index and thyroid function: insights from NHANES

Chen, J., Zhang, K., Wang, Y., Zhang, X., Xiong, G., Sun, X., Hou, N., Zhang, Y., & Kan, C. (2025) · HORMONES · doi:10.1007/s42000-025-00747-y · Cited by 1 · see citing works

Circulating thyroid hormones and metabolites in children with autism spectrum disorder

Hancock, M., Zhang, R., Brown, S. J., Boyder, C., Mullin, S., Campbell, P. J., Wilson, S. G., Lim, E., Whitehouse, A., & Walsh, J. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1716586 · Cited by 1 · see citing works

Causal validation of the relationship between 35 blood and urine biomarkers and hyperthyroidism: a bidirectional Mendelian randomization study and meta-analysis

Xu, W., Wu, J., Chen, D., Zhang, R., & Yang, Y. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1430798 · Cited by 1 · see citing works

A Two-Way Mendelian Randomization Analysis on the Link between Thyroid Activity Function and Coronary Atherosclerosis

Li, L., Leng, J., Luo, Y., Liu, R., Song, Z.-X., Ye, M., Li, Z.-H., Cao, Z.-R., Jiang, Y., & Tie, H. (2024) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2512453 · Cited by 1 · see citing works

Genetic drivers of etiologic heterogeneity in thyroid cancer

Jee, Y. H., Pozdeyev, N. V., Gignoux, C. R., White, S., Haugen, B. R., Verma, A., Pečulis, R., Rovīte, V., Mulford, A. J., Sanders, A. R., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-75111-8 · Cited by 1 · see citing works

Can Mendelian Randomization Bridge Two Common Endocrine Diseases in Fertile Women?

Brandt, N. B., Bonnema, S. J., & Bliddal, S. (2024) · Clinical Thyroidology · doi:10.1089/ct.2024;36.251-254

Removing array-specific batch effects in GWAS mega-analyses by applying a two-step imputation workflow reveals new associations for thyroid volume and goiterPreprint

Nasr, M. K., Koenig, E., Fuchsberger, C., Ghasemi, S., Völker, U., Voelzke, H., Grabe, H. J., & Teumer, A. (2024) · medRxiv · doi:10.1101/2024.11.21.24317711

Autoimmune and iodine deficiency diseases of the thyroid gland as the "tip of the iceberg" of multiple organ pathology

Troshina, E. A. (2024) · Terapevticheskii arkhiv · doi:10.26442/00403660.2024.10.202855

A Large GWAS for TSH Associations in Genetically Defined Cohorts Finds the Usual Suspects in New Combinations

Mhaimeed, N., & Mammen, J. S. (2025) · Clinical Thyroidology · doi:10.1089/ct.2025;37.126-129

Diagnosis of Hypothyroidism

Hoermann, R., & Dietrich, J. W. (2025) · Springer eBooks · doi:10.1007/978-981-96-3682-2_10

Bidirectional causal relationship between sleep disorders and thyroid function: a Mendelian randomization study

Zheng, K., Zhang, J., Shi, Z., Yang, Z., & Li, Z. (2025) · Biological Rhythm Research · doi:10.1080/09291016.2025.2525368

Unraveling the Genetic Link Between Endocrine Hormones and Psychiatric Disorders: An Atlas of Genetic Correlations

Li, J. L. (2025) · Endocrines · doi:10.3390/endocrines6030032

Investigating the Potential Causal Relationship Between Thyroid Function and Carpal Tunnel Syndrome: A Two-Sample Mendelian Randomization Study

Yu, H., & Wang, T. (2025) · Journal of the American Academy of Orthopaedic Surgeons · doi:10.5435/jaaos-d-25-00325

Genotype Combinations and Genetic Risk Score Analyses of MTHFR, MTRR, and MTR Polymorphisms in Hypothyroidism Susceptibility: A Case–Control Study

Tabakoğlu, N. T., Ay, A., Alkanlı, N., & Çelik, M. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47100794

Genetically Predicted Gastroesophageal Reflux Disease and Common Thyroid Disorders: A Two-sample Mendelian Randomization Study

Lv, H., Yang, X., Zhang, R., Xie, Y., Ni, X., Yang, X., & Shi, B. (2025) · Current Medicinal Chemistry · doi:10.2174/0109298673362752250730045645

Maternal thyroid hormone trajectories and cognitive develpoment in preschoolers: the Ma’anshan Birth Cohort

Li, W., Zhu, M., Wei, H., Zhang, M., Chen, S., Chen, L., Tong, J., Gao, G., Cao, H., Yan, S., et al. (2025) · Pediatric Research · doi:10.1038/s41390-025-04490-3

Exploring socio-economic, biochemical, and genetic factors influencing thyroid status in Indian school-going adolescents

Nair, J. M., Bandesh, K., Giri, A. K., Marwaha, R. K., Basu, A., Tandon, N., Chakraborty, S., & Bharadwaj, D. (2025) · Journal of Human Genetics · doi:10.1038/s10038-025-01432-z

GWAS of amiodarone-induced thyroid dysfunction: Applications for genotype-guided risk stratificationPreprint

Rand, S. A., Bundgaard, J. S., Tragante, V., Rögnvaldsson, S., Ahlberg, G., Small, A., Hornsby, W., Koyama, S., Schwinn, M., Kals, M., et al. (2026) · medRxiv · doi:10.64898/2026.03.02.26347413

Establishment of Reference Intervals for Plasma TSH Across the Lifespan in an Algerian Mediterranean Population

Ali, S. M., Boussaha, H., Nibou, L. A., Harhad, M., Nouali, M., Larab, Z., Messaoudene, D., Safer‐Tabi, A. F., Djidjeli, L., Merah, F., et al. (2026) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.70179

Widespread genetic effect heterogeneity impacts bias and power in nonlinear Mendelian randomizationPreprint

Wang, J., & Morrison, J. (2026) · medRxiv · doi:10.64898/2026.04.17.26351133

TSH reference intervals among Sub-Saharan African adults: a pilot study in Cameroon

Mbouna, S. F. M., Marcelle-Nourya Ymelong, M. E. L. I., EDINGA, B. E., ATABE, N. N., Stéphanie, Z. I. B. I., BETALA, M., Jean Maximilien, T. A. N. G., TANG-LIKENG, D. C., MFEKEU-KUATE, L., & Ama-Moor, V. J. (2026) · BMC Endocrine Disorders · doi:10.1186/s12902-026-02295-x

Thyroid function and risk of sepsis: a population-based prospective cohort study with traditional and genetic epidemiological analyses

Thorkildsen, M. S., Gustad, L. T., Åsvold, B. O., Mohus, R. M., Ellervik, C., Teumer, A., Marouli, E., Medici, M., Damås, J. K., Flatby, H. M., et al. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1852413

Integrated population-level and molecular evidence links nineteen aromatic amine antioxidants and six p-phenylenediamine quinones to thyroid homeostasis in older adults

Gao, Y., Cheng, L., Yu, Z., Zhu, Z., Peng, Y., Cheng, Z., Zhu, H., Sun, H., Li, H., & Zhao, H. (2026) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2026.143535

MSH5 Gene Polymorphisms Are Associated with Hashimoto’s Thyroiditis Susceptibility in a Chinese Han Population

Zhang, X., Jiang, Y., Xu, W., Li, G., Wang, Y., Qin, Q., Li, N., & Zhang, J. (2026) · Immunological Investigations · doi:10.1080/08820139.2026.2729081

Cell Type–Resolved Causal Inference and Spatial Transcriptomic Integration Reveal Immune‐Specific Genetic Drivers of Autoimmune and Malignant Thyroid Disease

Zhang, C., & Zhang, J. (2026) · International Journal of Immunogenetics · doi:10.1111/iji.70066

The Interplay Between Thyroid Cancer and Cardiovascular Disease: Shared Mechanisms, Treatment Implications, and Survivorship Perspectives

Bonab, L. N. H., Moazzam‐Jazi, M., Abooshahab, R., Heydarzadeh, S., DANESHPOUR, M. S., & Hedayati, M. (2026) · Cardiovascular Toxicology · doi:10.1007/s12012-026-10192-x

Insights into shared genetic architecture linking thyroid function and cancer

Wu, W., Zhang, W., Guo, J., Cheng, W., Liu, M., Li, L., Cai, H., & Jiang, L. (2026) · Endocrine Related Cancer · doi:10.1530/erc-26-0197

Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease

Williams, A. T., Chen, J., Coley, K., Batini, C., Izquierdo, A. G., Packer, R. J., Abner, E., Kanoni, S., Shepherd, D. J., Free, R. C., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-42284-5 · Cited by 28 · see citing works

Genetics of Thyroid Function: Relevance for Biology and Disease Management

Sterenborg, R. B. T. M., Peeters, R. P., Visser, W. E., Kuś, A., Smit, J. W. A., Teumer, A., & Medici, M. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaf491 · Cited by 2 · see citing works

The Genetic Basis of Thyroid Function: Novel Findings and New Approaches

Kuś, A., Chaker, L., Teumer, A., Peeters, R. P., & Medici, M. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgz225 · Cited by 44 · see citing works

A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function

Porcu, E., Medici, M., Pistis, G., Volpato, C. B., Wilson, S. G., Cappola, A. R., Bos, S. D., Deelen, J., den Heijer, M., Freathy, R. M., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003266 · Cited by 229 · see citing works

Testing for a causal role of thyroid hormone measurements within the normal range on human metabolism and diseases: a systematic Mendelian randomization

Alwan, H., Luan, J., Williamson, A., Carrasco-Zanini, J., Stewart, I. D., Wareham, N. J., Langenberg, C., & Pietzner, M. (2024) · EBioMedicine · doi:10.1016/j.ebiom.2024.105306 · Cited by 3 · see citing works