Ohashi, Pamela S.

LPS/TLR4 signal transduction pathway

Lu, Y.-C., Yeh, W.-C., & Ohashi, P. S. (2008) · Cytokine

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 3,301

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

Pagès, F., Mlecnik, B., Marliot, F., Bindea, G., Ou, F.-S., Bifulco, C., Lugli, A., Zlobec, I., Rau, T. T., Berger, M. D., et al. (2018) · The Lancet

Cancer Immunotherapy and BiomarkersColorectal Cancer Surgical Treatments

Cited by 2,075

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand.

Kong, Y.-Y., Feige, U., Sarosi, I., Bolon, B., Tafuri, A., Morony, S., Capparelli, C., Li, J., Elliott, R., McCabe, S., et al. (1999) · Nature

Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies

Cited by 1,856

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

Pfeffer, K., Matsuyama, T., Kündig, T. M., Wakeham, A., Kishihara, K., Shahinian, A., Wiegmann, K., Ohashi, P. S., Krönke, M., & Mak, T. W. (1993) · Cell

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 1,677

Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity

Hezaveh, K., Shinde, R. S., Klötgen, A., Halaby, M. J., Lamorte, S., Ciudad, M. T., Quevedo, R., Neufeld, L., Liu, Z. Q., Jin, R., et al. (2022) · Immunity

Immune cells in cancerCancer Immunotherapy and Biomarkers

Cited by 746

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

Matsuyama, T., Kimura, T., Kitagawa, M., Pfeffer, K., Kawakami, T., Watanabe, N., Kündig, T. M., Amakawa, R., Kishihara, K., Wakeham, A., et al. (1993) · Cell

interferon and immune responsesImmune Response and Inflammation

Cited by 649

Requirement for the Transcription Factor LSIRF/IRF4 for Mature B and T Lymphocyte Function

Mittrücker, H.-W., Matsuyama, T., Grossman, A., Kündig, T. M., Potter, J., Shahinian, A., Wakeham, A., Patterson, B., Ohashi, P. S., & Mak, T. W. (1997) · Science

T-cell and B-cell ImmunologyImmunodeficiency and Autoimmune Disorders

Cited by 583

The B7 family member B7-H3 preferentially down-regulates T helper type 1–mediated immune responses

Suh, W.-K., Gajewska, B. U., Okada, H., Gronski, M. A., Bertram, E. M., Dawicki, W., Duncan, G. S., Bukczynski, J., Plyte, S., Elia, A., et al. (2003) · Nature Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 576

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

Sasaki, M., Knobbe, C. B., Munger, J. C., Lind, E. F., Brenner, D., Brüstle, A., Harris, I. S., Holmes, R., Wakeham, A., Haight, J., et al. (2012) · Nature

Acute Myeloid Leukemia ResearchGlioma Diagnosis and Treatment

Cited by 513

Personalized circulating tumor DNA analysis as a predictive biomarker in solid tumor patients treated with pembrolizumab

Bratman, S. V., Yang, S. Y. C., Iafolla, M. A. J., Liu, Z., Hansen, A. R., Bedard, P. L., Lheureux, S., Spreafico, A., Razak, A. A., Shchegrova, S., et al. (2020) · Nature Cancer

Cancer Immunotherapy and BiomarkersCancer Genomics and Diagnostics

Cited by 487

Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction

Jeon, M.-S., Atfield, A., Venuprasad, K., Krawczyk, C., Sarao, R., Elly, C., Yang, C., Arya, S., Bachmaier, K., Su, L., et al. (2004) · Immunity

T-cell and B-cell ImmunologyImmune Response and Inflammation

Cited by 348

Mechanical stiffness controls dendritic cell metabolism and function

Chakraborty, M., Chu, K., Shrestha, A., Revelo, X. S., Zhang, X., Gold, M. J., Khan, S., Lee, M., Huang, C., Akbari, M., et al. (2021) · Cell Reports

Cellular Mechanics and InteractionsImmunotherapy and Immune Responses

Cited by 258

A point mutation in CD28 distinguishes proliferative signals from survival signals.

Okkenhaug, K., Wu, L., Garza, K. M., La Rose, J., Khoo, W., Odermatt, B., Mak, T. W., Ohashi, P. S., & Rottapel, R. (2001) · Nature Immunology

T-cell and B-cell ImmunologySignaling Pathways in Disease

Cited by 210

Essential Role for Caspase-8 in Toll-like Receptors and NFκB Signaling

Lemmers, B., Salmena, L., Bidère, N., Su, H., Matysiak-Zablocki, E., Murakami, K., Ohashi, P. S., Jurisicova, A., Lenardo, M., Hakem, R., et al. (2007) · Journal of Biological Chemistry

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 181

Choline acetyltransferase-expressing T cells are required to control chronic viral infection

Cox, M. A., Duncan, G. S., Lin, G. H. Y., Steinberg, B. E., Yu, L. X., Brenner, D., Buckler, L. N., Elia, A. J., Wakeham, A. C., Nieman, B., et al. (2019) · Science

T-cell and B-cell ImmunologyVagus Nerve Stimulation Research

Cited by 155

A Four-Chemokine Signature Is Associated with a T-cell–Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer

Romero, J. M., Grünwald, B., Jang, G.-H., Bavi, P. P., Jhaveri, A., Masoomian, M., Fischer, S. E., Zhang, A., Denroche, R. E., Lungu, I. M., et al. (2020) · Clinical Cancer Research

Pancreatic and Hepatic Oncology ResearchCancer Immunotherapy and Biomarkers

Cited by 146

An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function

Zheng, W., Umitsu, M., Jagan, I., Tran, C. W., Ishiyama, N., BeGora, M., Araki, K., Ohashi, P. S., Ikura, M., & Muthuswamy, S. K. (2016) · Nature Cell Biology

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 60